SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_1
(ALCOHOL
DEHYDROGENASE)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		4 / 4 GLU A 504
MET A 496
LEU A 501
SER A 502
 None
 1.34A 1ee2B-1eovA:
0.0		 1ee2B-1eovA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		4 / 5 GLY A 139
LEU A 128
THR A 129
VAL A 168
 None
 1.01A 1ekjF-1eovA:
undetectable
1ekjG-1eovA:
undetectable		 1ekjF-1eovA:
18.14
1ekjG-1eovA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 188
HIS A 190
ASP A 176
 None
 0.82A 1i9gA-1eovA:
undetectable		 1i9gA-1eovA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		5 / 11 GLY A 526
GLY A 528
ILE A 479
GLY A 482
LEU A 358
 None
 1.06A 1jg3A-1eovA:
undetectable		 1jg3A-1eovA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		5 / 11 GLY A 526
GLY A 528
ILE A 479
GLY A 482
LEU A 358
 None
 1.05A 1jg3B-1eovA:
undetectable		 1jg3B-1eovA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 130
LEU A 136
ALA A 246
GLN A 132
HIS A 375
 None
 1.32A 1kt7A-1eovA:
0.0		 1kt7A-1eovA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		5 / 11 THR A 196
VAL A 115
ASN A 161
GLU A 199
GLU A 202
 None
 1.04A 1t6zA-1eovA:
undetectable		 1t6zA-1eovA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 551
ARG A 550
ARG A 554
 None
 1.10A 2j9dA-1eovA:
1.8
2j9dC-1eovA:
1.6		 2j9dA-1eovA:
14.70
2j9dC-1eovA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 523
GLY A 482
GLY A 526
ASN A 468
PHE A 347
 None
 1.10A 2okcB-1eovA:
undetectable		 2okcB-1eovA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 433
ALA A 411
GLY A 413
PHE A 429
 None
 0.91A 2wq5A-1eovA:
0.0		 2wq5A-1eovA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		5 / 11 VAL A 141
LEU A 140
GLY A 139
ILE A 137
THR A 118
 None
 1.19A 3bjwH-1eovA:
undetectable		 3bjwH-1eovA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		3 / 3 VAL A  97
LYS A  95
HIS A 116
 None
 0.85A 3elzA-1eovA:
0.0		 3elzA-1eovA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 112
GLU A 163
ASP A 238
 None
 0.80A 3g2oA-1eovA:
0.2		 3g2oA-1eovA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 525
GLY A 524
LEU A 355
SER A 359
ASP A 471
 None
 1.07A 3i5uB-1eovA:
undetectable		 3i5uB-1eovA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		4 / 8 TYR A 195
GLY A 147
SER A 150
ILE A 149
 None
 0.79A 3ihzB-1eovA:
undetectable		 3ihzB-1eovA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 499
SER A 280
GLU A 281
 None
 0.78A 3s8pA-1eovA:
undetectable		 3s8pA-1eovA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 377
LEU A 537
VAL A 254
GLY A 253
 None
 0.89A 3w1wA-1eovA:
undetectable		 3w1wA-1eovA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 515
TYR A 511
THR A 457
PHE A 455
 None
 1.19A 4jx1E-1eovA:
undetectable		 4jx1E-1eovA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 197
ILE A 149
GLY A 170
LYS A  95
ILE A 191
 None
 1.05A 4o1eA-1eovA:
undetectable		 4o1eA-1eovA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 197
ILE A 149
GLY A 170
LYS A  95
ILE A 191
 None
 1.03A 4o1eB-1eovA:
undetectable		 4o1eB-1eovA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		4 / 6 GLY A 526
PHE A 362
ILE A 479
PHE A 366
 None
 0.97A 4qogA-1eovA:
0.0
4qogB-1eovA:
0.0		 4qogA-1eovA:
18.76
4qogB-1eovA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 140
ALA A 143
ASN A 144
ILE A 149
 None
 1.05A 4y03B-1eovA:
undetectable		 4y03B-1eovA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 130
LEU A 140
GLY A 139
LEU A 128
ALA A 126
 None
 1.12A 5dqfA-1eovA:
undetectable		 5dqfA-1eovA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 166
THR A 196
LEU A 128
THR A 118
 None
 1.04A 5e4dA-1eovA:
0.0
5e4dB-1eovA:
0.0		 5e4dA-1eovA:
18.31
5e4dB-1eovA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 137
LEU A 130
ARG A 169
ILE A 191
GLY A 170
 None
 1.09A 5ifuB-1eovA:
7.7		 5ifuB-1eovA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA609_0
(ACETYLCHOLINESTERASE)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		4 / 6 TYR A 511
ASP A 513
HIS A 489
TYR A 456
 None
 1.45A 5ov9A-1eovA:
undetectable		 5ov9A-1eovA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 511
ASP A 513
HIS A 489
TYR A 456
 None
 1.43A 5ov9B-1eovA:
0.0		 5ov9B-1eovA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 527
PHE A 267
THR A 357
THR A 272
 None
 0.89A 5vc0A-1eovA:
0.9		 5vc0A-1eovA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		5 / 10 ARG A 325
HIS A 334
PHE A 338
GLY A 528
ILE A 542
 None
 1.01A 6bniA-1eovA:
27.7		 6bniA-1eovA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)		 1eov ASPARTYL-TRNA
SYNTHETASE
(Saccharomyces
cerevisiae) 		5 / 10 ARG A 325
HIS A 334
PHE A 338
GLY A 528
ILE A 542
 None
 0.99A 6bniB-1eovA:
28.0		 6bniB-1eovA:
9.75