SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eq2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 1eq2 ADP-L-GLYCERO-D-MANN
OHEPTOSE 6-EPIMERASE
(Escherichia
coli) 		5 / 12 GLY A   9
GLY A   7
ILE A  15
LEU A  33
ASP A  35
 NAP  A2400 (-3.4A)
None
None
None
None
 1.04A 1x1aA-1eq2A:
4.9		 1x1aA-1eq2A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 1eq2 ADP-L-GLYCERO-D-MANN
OHEPTOSE 6-EPIMERASE
(Escherichia
coli) 		4 / 7 ASP A  31
THR A   5
ILE A  15
ASN A 221
 NAP  A2400 (-2.8A)
NAP  A2400 ( 4.4A)
None
None
 1.24A 2jc9A-1eq2A:
2.7		 2jc9A-1eq2A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1eq2 ADP-L-GLYCERO-D-MANN
OHEPTOSE 6-EPIMERASE
(Escherichia
coli) 		5 / 12 SER A  79
GLY A   9
GLY A  76
ALA A  77
LYS A 178
 NAP  A2400 (-3.3A)
NAP  A2400 (-3.4A)
NAP  A2400 (-3.3A)
CSO  A  78 (-3.0A)
NAP  A2400 (-2.7A)
 1.01A 2nyuA-1eq2A:
6.2		 2nyuA-1eq2A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1eq2 ADP-L-GLYCERO-D-MANN
OHEPTOSE 6-EPIMERASE
(Escherichia
coli) 		4 / 6 PHE A 292
ARG A 239
GLY A 238
ALA A 278
 None
 0.95A 3bgdA-1eq2A:
2.7		 3bgdA-1eq2A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		 1eq2 ADP-L-GLYCERO-D-MANN
OHEPTOSE 6-EPIMERASE
(Escherichia
coli) 		4 / 7 TYR A 167
ASN A 221
ILE A  11
PHE A  10
 NAP  A2400 (-4.6A)
None
NAP  A2400 (-3.8A)
NAP  A2400 (-4.9A)
 1.15A 3tvxB-1eq2A:
undetectable		 3tvxB-1eq2A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 1eq2 ADP-L-GLYCERO-D-MANN
OHEPTOSE 6-EPIMERASE
(Escherichia
coli) 		4 / 5 VAL A 163
GLY A 231
TYR A 113
ASP A 148
 None
 1.37A 3w9tB-1eq2A:
0.0		 3w9tB-1eq2A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 1eq2 ADP-L-GLYCERO-D-MANN
OHEPTOSE 6-EPIMERASE
(Escherichia
coli) 		4 / 5 VAL A 163
GLY A 231
TYR A 113
ASP A 148
 None
 1.38A 3w9tC-1eq2A:
0.0		 3w9tC-1eq2A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 1eq2 ADP-L-GLYCERO-D-MANN
OHEPTOSE 6-EPIMERASE
(Escherichia
coli) 		4 / 5 VAL A 163
GLY A 231
TYR A 113
ASP A 148
 None
 1.37A 3w9tD-1eq2A:
0.0		 3w9tD-1eq2A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 1eq2 ADP-L-GLYCERO-D-MANN
OHEPTOSE 6-EPIMERASE
(Escherichia
coli) 		4 / 5 VAL A 163
GLY A 231
TYR A 113
ASP A 148
 None
 1.37A 3w9tE-1eq2A:
0.0		 3w9tE-1eq2A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 1eq2 ADP-L-GLYCERO-D-MANN
OHEPTOSE 6-EPIMERASE
(Escherichia
coli) 		4 / 5 VAL A 163
GLY A 231
TYR A 113
ASP A 148
 None
 1.37A 3w9tG-1eq2A:
0.0		 3w9tG-1eq2A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1eq2 ADP-L-GLYCERO-D-MANN
OHEPTOSE 6-EPIMERASE
(Escherichia
coli) 		4 / 5 THR A  81
THR A  82
HIS A 187
ASN A 169
 ADQ  A2500 (-4.0A)
None
ADQ  A2500 (-3.8A)
ADQ  A2500 (-3.7A)
 1.16A 4pgfB-1eq2A:
6.3		 4pgfB-1eq2A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1eq2 ADP-L-GLYCERO-D-MANN
OHEPTOSE 6-EPIMERASE
(Escherichia
coli) 		3 / 3 SER A 116
ALA A 117
THR A 276
 NAP  A2400 (-3.1A)
None
None
 0.51A 5n0xB-1eq2A:
0.0		 5n0xB-1eq2A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_A_SAMA401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 1eq2 ADP-L-GLYCERO-D-MANN
OHEPTOSE 6-EPIMERASE
(Escherichia
coli) 		5 / 12 TYR A 213
LEU A 235
GLY A 236
SER A 183
VAL A 295
 None
 1.47A 6bxlA-1eq2A:
0.0		 6bxlA-1eq2A:
23.15