SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eqn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.33A 1a4gB-1eqnA:
undetectable		 1a4gB-1eqnA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		4 / 5 LEU A 407
LEU A 411
SER A 375
LEU A 376
 None
 0.96A 1a4lC-1eqnA:
undetectable		 1a4lC-1eqnA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1eqn DNA PRIMASE
(Escherichia
coli) 		4 / 6 LEU A 296
GLN A 295
PHE A 298
LEU A 245
 None
 1.03A 2zxwP-1eqnA:
undetectable
2zxwW-1eqnA:
0.0		 2zxwP-1eqnA:
20.43
2zxwW-1eqnA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_A_4PZA501_1
(CYTOCHROME P450 2E1)		 1eqn DNA PRIMASE
(Escherichia
coli) 		3 / 3 ALA A 321
THR A 289
CYH A 306
 None
 0.75A 3e4eA-1eqnA:
undetectable		 3e4eA-1eqnA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_B_4PZB501_1
(CYTOCHROME P450 2E1)		 1eqn DNA PRIMASE
(Escherichia
coli) 		3 / 3 ALA A 321
THR A 289
CYH A 306
 None
 0.76A 3e4eB-1eqnA:
undetectable		 3e4eB-1eqnA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_0
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.12A 3k37A-1eqnA:
undetectable		 3k37A-1eqnA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.10A 3k39A-1eqnA:
undetectable		 3k39A-1eqnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.11A 3k39C-1eqnA:
undetectable		 3k39C-1eqnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.11A 3k39E-1eqnA:
undetectable		 3k39E-1eqnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.13A 3k39F-1eqnA:
undetectable		 3k39F-1eqnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.10A 3k39G-1eqnA:
undetectable		 3k39G-1eqnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.12A 3k39H-1eqnA:
undetectable		 3k39H-1eqnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.11A 3k39I-1eqnA:
undetectable		 3k39I-1eqnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.12A 3k39J-1eqnA:
undetectable		 3k39J-1eqnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.11A 3k39K-1eqnA:
undetectable		 3k39K-1eqnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.10A 3k39L-1eqnA:
undetectable		 3k39L-1eqnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.11A 3k39M-1eqnA:
undetectable		 3k39M-1eqnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.09A 3k39O-1eqnA:
undetectable		 3k39O-1eqnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1eqn DNA PRIMASE
(Escherichia
coli) 		4 / 4 VAL A 271
PHE A 206
PHE A 218
VAL A 215
 None
 1.33A 3rv5C-1eqnA:
0.3
3rv5D-1eqnA:
0.0		 3rv5C-1eqnA:
16.94
3rv5D-1eqnA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.30A 4cpnB-1eqnA:
undetectable		 4cpnB-1eqnA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		4 / 4 LEU A 419
ILE A 399
GLY A 416
PHE A 373
 None
 1.13A 4dc3A-1eqnA:
undetectable		 4dc3A-1eqnA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ILE A 216
MET A 187
PHE A 239
LEU A 285
ILE A 208
 None
 1.08A 4kjkA-1eqnA:
undetectable		 4kjkA-1eqnA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.28A 4mwrA-1eqnA:
undetectable		 4mwrA-1eqnA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.31A 4mwxA-1eqnA:
undetectable		 4mwxA-1eqnA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 11 ARG A 146
LEU A 143
ARG A 221
LEU A 148
LEU A 131
 None
 1.39A 4or0A-1eqnA:
2.1		 4or0A-1eqnA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		4 / 6 LEU A 407
SER A 369
PRO A 367
PHE A 371
 None
 1.20A 5b8iA-1eqnA:
0.1		 5b8iA-1eqnA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.22A 5l17A-1eqnA:
undetectable		 5l17A-1eqnA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_0
(NEURAMINIDASE)		 1eqn DNA PRIMASE
(Escherichia
coli) 		5 / 12 ARG A 260
GLU A 363
ARG A 336
ARG A 361
GLU A 353
 None
 1.29A 6hcxA-1eqnA:
undetectable		 6hcxA-1eqnA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 1eqn DNA PRIMASE
(Escherichia
coli) 		4 / 6 MET A 187
LEU A 188
MET A 120
THR A 236
 None
 1.06A 6mvxA-1eqnA:
undetectable
6mvxB-1eqnA:
undetectable
6mvxC-1eqnA:
undetectable		 6mvxA-1eqnA:
20.62
6mvxB-1eqnA:
20.62
6mvxC-1eqnA:
20.62