SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  69
ASP A 130
GLY A 138
HIS A  44
HIS A  46
 ZN  A 149 ( 3.0A)
None
None
CU  A 150 ( 3.2A)
CU  A 150 ( 3.3A)
 1.49A 1a4lD-1esoA:
undetectable		 1a4lD-1esoA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.38A 1d4fC-1esoA:
undetectable		 1d4fC-1esoA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 LEU A  85
GLY A  42
LEU A  36
SER A  30
PRO A  31
 None
 1.06A 1dfoA-1esoA:
undetectable		 1dfoA-1esoA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 LEU A  85
GLY A  42
LEU A  36
SER A  30
PRO A  31
 None
 1.06A 1dfoB-1esoA:
undetectable		 1dfoB-1esoA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 LEU A  85
GLY A  42
LEU A  36
SER A  30
PRO A  31
 None
 1.06A 1dfoC-1esoA:
undetectable		 1dfoC-1esoA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 LEU A  85
GLY A  42
LEU A  36
SER A  30
PRO A  31
 None
 1.06A 1dfoD-1esoA:
undetectable		 1dfoD-1esoA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 LEU A  85
GLY A  42
LEU A  36
SER A  30
PRO A  31
 None
 1.10A 1eqbA-1esoA:
undetectable		 1eqbA-1esoA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 LEU A  85
GLY A  42
LEU A  36
SER A  30
PRO A  31
 None
 1.09A 1eqbB-1esoA:
undetectable		 1eqbB-1esoA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 LEU A  85
GLY A  42
LEU A  36
SER A  30
PRO A  31
 None
 1.09A 1eqbC-1esoA:
undetectable		 1eqbC-1esoA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 LEU A  85
GLY A  42
LEU A  36
SER A  30
PRO A  31
 None
 1.09A 1eqbD-1esoA:
undetectable		 1eqbD-1esoA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A 118
GLY A 138
GLU A  40
HIS A  44
PRO A  83
 CU  A 150 ( 3.2A)
None
None
CU  A 150 ( 3.2A)
None
 1.10A 1mj2C-1esoA:
undetectable
1mj2D-1esoA:
undetectable		 1mj2C-1esoA:
21.62
1mj2D-1esoA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A 118
GLY A 138
GLU A  40
HIS A  44
PRO A  83
 CU  A 150 ( 3.2A)
None
None
CU  A 150 ( 3.2A)
None
 1.12A 1mjoC-1esoA:
undetectable
1mjoD-1esoA:
undetectable		 1mjoC-1esoA:
21.62
1mjoD-1esoA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A 118
GLY A 138
GLU A  40
HIS A  44
PRO A  83
 CU  A 150 ( 3.2A)
None
None
CU  A 150 ( 3.2A)
None
 1.13A 1mjqC-1esoA:
undetectable
1mjqD-1esoA:
undetectable		 1mjqC-1esoA:
21.62
1mjqD-1esoA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A 118
GLY A 138
GLU A  40
HIS A  44
PRO A  83
 CU  A 150 ( 3.2A)
None
None
CU  A 150 ( 3.2A)
None
 1.12A 1mjqI-1esoA:
undetectable
1mjqJ-1esoA:
undetectable		 1mjqI-1esoA:
21.62
1mjqJ-1esoA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.51A 1rjoA-1esoA:
undetectable		 1rjoA-1esoA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.56A 1rkyA-1esoA:
undetectable		 1rkyA-1esoA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.61A 1v54A-1esoA:
undetectable		 1v54A-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.61A 1v54N-1esoA:
undetectable		 1v54N-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.62A 1v55A-1esoA:
undetectable		 1v55A-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.64A 1v55N-1esoA:
undetectable		 1v55N-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.50A 1w2zA-1esoA:
undetectable		 1w2zA-1esoA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.48A 1w2zB-1esoA:
undetectable		 1w2zB-1esoA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.48A 1w2zC-1esoA:
undetectable		 1w2zC-1esoA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.49A 1w2zD-1esoA:
undetectable		 1w2zD-1esoA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.60A 2dyrA-1esoA:
undetectable		 2dyrA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.62A 2dyrN-1esoA:
undetectable		 2dyrN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.56A 2dysA-1esoA:
undetectable		 2dysA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.54A 2dysN-1esoA:
undetectable		 2dysN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.60A 2eijA-1esoA:
undetectable		 2eijA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.62A 2eijN-1esoA:
undetectable		 2eijN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.58A 2eikA-1esoA:
undetectable		 2eikA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.63A 2eikN-1esoA:
undetectable		 2eikN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.57A 2eilA-1esoA:
undetectable		 2eilA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.61A 2eilN-1esoA:
undetectable		 2eilN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.66A 2eimA-1esoA:
undetectable		 2eimA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.61A 2eimN-1esoA:
undetectable		 2eimN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.50A 2einA-1esoA:
undetectable		 2einA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.62A 2einN-1esoA:
undetectable		 2einN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 ALA A  58
SER A  57
ALA A  53
ALA A  47
GLY A  49
 None
 1.31A 2igtC-1esoA:
undetectable		 2igtC-1esoA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.44A 2oqeA-1esoA:
undetectable		 2oqeA-1esoA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.43A 2oqeB-1esoA:
undetectable		 2oqeB-1esoA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.45A 2oqeC-1esoA:
undetectable		 2oqeC-1esoA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.44A 2oqeD-1esoA:
undetectable		 2oqeD-1esoA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.44A 2oqeF-1esoA:
undetectable		 2oqeF-1esoA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A 118
ASP A  54
GLY A  60
HIS A  46
HIS A  44
 CU  A 150 ( 3.2A)
None
None
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 1.11A 2pgrA-1esoA:
undetectable		 2pgrA-1esoA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.56A 2w0qA-1esoA:
undetectable		 2w0qA-1esoA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.50A 2w0qB-1esoA:
undetectable		 2w0qB-1esoA:
12.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		4 / 4 HIS A  44
HIS A  46
HIS A  61
HIS A 118
 CU  A 150 ( 3.2A)
CU  A 150 ( 3.3A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.2A)
 0.22A 2wkoA-1esoA:
19.3		 2wkoA-1esoA:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		4 / 5 HIS A  44
HIS A  46
HIS A  61
HIS A 118
 CU  A 150 ( 3.2A)
CU  A 150 ( 3.3A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.2A)
 0.23A 2wkoF-1esoA:
19.3		 2wkoF-1esoA:
32.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.61A 2y69A-1esoA:
undetectable		 2y69A-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.65A 2y69N-1esoA:
undetectable		 2y69N-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 ALA A 143
THR A  10
GLY A  10
LEU A  85
ASN A   9
 None
 1.01A 2y7hB-1esoA:
undetectable		 2y7hB-1esoA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 ALA A 143
THR A  10
GLY A  10
LEU A  85
ASN A   9
 None
 1.00A 2y7hC-1esoA:
undetectable		 2y7hC-1esoA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.19A 2zj0B-1esoA:
undetectable		 2zj0B-1esoA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.14A 2zj0C-1esoA:
undetectable		 2zj0C-1esoA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.59A 2zxwA-1esoA:
undetectable		 2zxwA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.60A 2zxwN-1esoA:
undetectable		 2zxwN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.62A 3abkA-1esoA:
undetectable		 3abkA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.62A 3abkN-1esoA:
undetectable		 3abkN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.56A 3ablA-1esoA:
undetectable		 3ablA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.54A 3ablN-1esoA:
undetectable		 3ablN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.62A 3abmA-1esoA:
undetectable		 3abmA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.59A 3abmN-1esoA:
undetectable		 3abmN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.66A 3ag1A-1esoA:
undetectable		 3ag1A-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.68A 3ag1N-1esoA:
undetectable		 3ag1N-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.60A 3ag2A-1esoA:
undetectable		 3ag2A-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.62A 3ag2N-1esoA:
undetectable		 3ag2N-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.62A 3ag3A-1esoA:
undetectable		 3ag3A-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.62A 3ag3N-1esoA:
undetectable		 3ag3N-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.74A 3ag4N-1esoA:
undetectable		 3ag4N-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.61A 3asnA-1esoA:
undetectable		 3asnA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.61A 3asnN-1esoA:
undetectable		 3asnN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.61A 3asoA-1esoA:
undetectable		 3asoA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.59A 3asoN-1esoA:
undetectable		 3asoN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		4 / 6 HIS A  41
PHE A  43
LEU A  36
LEU A  33
 None
 1.18A 3bgdA-1esoA:
0.0		 3bgdA-1esoA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.64A 3bvdA-1esoA:
undetectable		 3bvdA-1esoA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.24A 3ce6B-1esoA:
undetectable		 3ce6B-1esoA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.68A 3dtuA-1esoA:
undetectable		 3dtuA-1esoA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.69A 3dtuC-1esoA:
undetectable		 3dtuC-1esoA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.28A 3g1uB-1esoA:
undetectable		 3g1uB-1esoA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.33A 3g1uD-1esoA:
undetectable		 3g1uD-1esoA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.29A 3glqA-1esoA:
undetectable		 3glqA-1esoA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.27A 3glqB-1esoA:
undetectable		 3glqB-1esoA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.44A 3hiiA-1esoA:
undetectable		 3hiiA-1esoA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
HIS A  46
HIS A  44
 ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
CU  A 150 ( 3.2A)
 0.46A 3hiiB-1esoA:
undetectable		 3hiiB-1esoA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A 118
HIS A  46
MET A 116
 CU  A 150 ( 3.2A)
CU  A 150 ( 3.3A)
None
 1.04A 3mihA-1esoA:
0.0		 3mihA-1esoA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.34A 3n58A-1esoA:
undetectable		 3n58A-1esoA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.29A 3n58C-1esoA:
undetectable		 3n58C-1esoA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 LEU A  85
ALA A 143
GLY A 145
ALA A  55
HIS A 118
 None
None
None
None
CU  A 150 ( 3.2A)
 1.14A 3ou6B-1esoA:
undetectable		 3ou6B-1esoA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 ILE A 110
ALA A  99
LEU A  27
GLY A  71
PRO A  72
 None
 0.99A 3ozwB-1esoA:
undetectable		 3ozwB-1esoA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.64A 3s33A-1esoA:
undetectable		 3s33A-1esoA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.66A 3s38A-1esoA:
undetectable		 3s38A-1esoA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.61A 3s39A-1esoA:
undetectable		 3s39A-1esoA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.68A 3s3aA-1esoA:
undetectable		 3s3aA-1esoA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.65A 3s3bA-1esoA:
undetectable		 3s3bA-1esoA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.64A 3s3cA-1esoA:
undetectable		 3s3cA-1esoA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.58A 3s3dA-1esoA:
undetectable		 3s3dA-1esoA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  46
SER A  54
GLU A  56
 CU  A 150 ( 3.3A)
None
None
 0.82A 3s8pA-1esoA:
0.0		 3s8pA-1esoA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.58A 3wg7A-1esoA:
undetectable		 3wg7A-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.61A 3wg7N-1esoA:
undetectable		 3wg7N-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.61A 3x2qA-1esoA:
undetectable		 3x2qA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.66A 3x2qN-1esoA:
undetectable		 3x2qN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.59A 5b1aA-1esoA:
undetectable		 5b1aA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.61A 5b1aN-1esoA:
undetectable		 5b1aN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.63A 5b1bA-1esoA:
undetectable		 5b1bA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.63A 5b1bN-1esoA:
undetectable		 5b1bN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.61A 5b3sA-1esoA:
undetectable		 5b3sA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.63A 5b3sN-1esoA:
undetectable		 5b3sN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 LEU A  33
PRO A  83
LEU A 102
PHE A  29
ILE A  45
 None
 1.47A 5dv4A-1esoA:
undetectable		 5dv4A-1esoA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.63A 5iy5A-1esoA:
undetectable		 5iy5A-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.63A 5iy5N-1esoA:
undetectable		 5iy5N-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  61
ASP A  81
HIS A  69
 ZN  A 149 ( 3.2A)
ZN  A 149 ( 2.4A)
ZN  A 149 ( 3.0A)
 0.79A 5n1tW-1esoA:
undetectable		 5n1tW-1esoA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  78
ASP A  81
HIS A  69
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
ZN  A 149 ( 3.0A)
 0.91A 5n1tW-1esoA:
undetectable		 5n1tW-1esoA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.67A 5w97a-1esoA:
undetectable		 5w97a-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.64A 5waua-1esoA:
undetectable		 5waua-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.64A 5x19A-1esoA:
undetectable		 5x19A-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.66A 5x19N-1esoA:
undetectable		 5x19N-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.65A 5x1bA-1esoA:
undetectable		 5x1bA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.65A 5x1bN-1esoA:
undetectable		 5x1bN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.67A 5x1fA-1esoA:
undetectable		 5x1fA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.67A 5x1fN-1esoA:
undetectable		 5x1fN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.59A 5xdqA-1esoA:
undetectable		 5xdqA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.61A 5xdqN-1esoA:
undetectable		 5xdqN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.63A 5xdxA-1esoA:
undetectable		 5xdxA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.64A 5xdxN-1esoA:
undetectable		 5xdxN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.57A 5z84A-1esoA:
undetectable		 5z84A-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.60A 5z84N-1esoA:
undetectable		 5z84N-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.59A 5z85A-1esoA:
undetectable		 5z85A-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.59A 5z85N-1esoA:
undetectable		 5z85N-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.57A 5z86A-1esoA:
undetectable		 5z86A-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.62A 5z86N-1esoA:
undetectable		 5z86N-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.59A 5zcoA-1esoA:
undetectable		 5zcoA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.58A 5zcoN-1esoA:
undetectable		 5zcoN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.57A 5zcpA-1esoA:
undetectable		 5zcpA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.60A 5zcpN-1esoA:
undetectable		 5zcpN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.56A 5zcqA-1esoA:
undetectable		 5zcqA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.57A 5zcqN-1esoA:
undetectable		 5zcqN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		4 / 4 HIS A  44
HIS A 118
HIS A  46
HIS A  61
 CU  A 150 ( 3.2A)
CU  A 150 ( 3.2A)
CU  A 150 ( 3.3A)
ZN  A 149 ( 3.2A)
 1.18A 5zrdC-1esoA:
undetectable		 5zrdC-1esoA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		4 / 4 HIS A  44
HIS A 118
HIS A  46
HIS A  61
 CU  A 150 ( 3.2A)
CU  A 150 ( 3.2A)
CU  A 150 ( 3.3A)
ZN  A 149 ( 3.2A)
 1.17A 5zrdD-1esoA:
undetectable		 5zrdD-1esoA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		4 / 5 PRO A  83
VAL A  97
GLY A 145
VAL A 117
 None
 1.09A 6ak3B-1esoA:
undetectable		 6ak3B-1esoA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.25A 6aphA-1esoA:
undetectable		 6aphA-1esoA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_1
(-)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.34A 6f3mA-1esoA:
0.0		 6f3mA-1esoA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_1
(-)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.34A 6f3mC-1esoA:
0.0		 6f3mC-1esoA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_1
(-)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.28A 6f3nA-1esoA:
undetectable		 6f3nA-1esoA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_1
(-)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.38A 6f3nC-1esoA:
undetectable		 6f3nC-1esoA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_1
(-)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		5 / 12 HIS A  78
ASP A  81
LEU A 135
GLY A  60
HIS A  46
 ZN  A 149 ( 3.0A)
ZN  A 149 ( 2.4A)
None
None
CU  A 150 ( 3.3A)
 1.27A 6f3nD-1esoA:
undetectable		 6f3nD-1esoA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.67A 6hu9a-1esoA:
undetectable		 6hu9a-1esoA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.65A 6hu9m-1esoA:
undetectable		 6hu9m-1esoA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.59A 6nknA-1esoA:
undetectable		 6nknA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.57A 6nknN-1esoA:
undetectable		 6nknN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.64A 6nmfA-1esoA:
undetectable		 6nmfA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.68A 6nmfN-1esoA:
undetectable		 6nmfN-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.65A 6nmpA-1esoA:
undetectable		 6nmpA-1esoA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1eso CU, ZN SUPEROXIDE
DISMUTASE
(Escherichia
coli) 		3 / 3 HIS A  44
HIS A  61
HIS A  46
 CU  A 150 ( 3.2A)
ZN  A 149 ( 3.2A)
CU  A 150 ( 3.3A)
 0.62A 6nmpN-1esoA:
undetectable		 6nmpN-1esoA:
17.66