SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1et9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1et9 SUPERANTIGEN SPE-H
(Streptococcus
pyogenes) 		5 / 10 TYR A 172
ILE A 139
ILE A 144
GLY A 155
LEU A  11
 None
 1.28A 3elzB-1et9A:
0.0		 3elzB-1et9A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 1et9 SUPERANTIGEN SPE-H
(Streptococcus
pyogenes) 		4 / 7 LEU A 161
GLN A 128
LEU A 171
LEU A  71
 None
 0.75A 3g8iA-1et9A:
undetectable		 3g8iA-1et9A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 1et9 SUPERANTIGEN SPE-H
(Streptococcus
pyogenes) 		5 / 12 ASP A 131
VAL A 168
GLY A 155
ILE A 203
VAL A 199
 None
 1.12A 3mwsB-1et9A:
undetectable		 3mwsB-1et9A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1et9 SUPERANTIGEN SPE-H
(Streptococcus
pyogenes) 		3 / 3 TYR A 173
LEU A 137
LYS A 136
 None
 0.48A 3sueD-1et9A:
0.0		 3sueD-1et9A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 1et9 SUPERANTIGEN SPE-H
(Streptococcus
pyogenes) 		5 / 12 GLN A 128
GLY A  89
PHE A  51
SER A  49
GLU A  23
 None
 1.17A 3t7sA-1et9A:
undetectable		 3t7sA-1et9A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Q1S_A_AWYA1103_0
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 1et9 SUPERANTIGEN SPE-H
(Streptococcus
pyogenes) 		4 / 6 VAL A  50
LYS A  40
ILE A  68
LYS A  46
 None
 1.45A 5q1sA-1et9A:
undetectable		 5q1sA-1et9A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 1et9 SUPERANTIGEN SPE-H
(Streptococcus
pyogenes) 		3 / 3 LEU A 138
LEU A 171
ARG A 135
 None
 0.64A 6fgcA-1et9A:
0.0		 6fgcA-1et9A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 1et9 SUPERANTIGEN SPE-H
(Streptococcus
pyogenes) 		3 / 3 LEU A 138
LEU A 171
ARG A 135
 None
 0.61A 6fgdA-1et9A:
undetectable		 6fgdA-1et9A:
18.68