SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eth'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 8 ASP A 106
HIS A  76
GLY A 109
GLY A 110
 None
 0.86A 1ekjA-1ethA:
undetectable
1ekjB-1ethA:
undetectable		 1ekjA-1ethA:
18.38
1ekjB-1ethA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 7 ASP A 106
HIS A  76
GLY A 109
GLY A 110
 None
 0.89A 1ekjE-1ethA:
undetectable
1ekjF-1ethA:
undetectable		 1ekjE-1ethA:
18.38
1ekjF-1ethA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 8 ASP A 106
HIS A  76
GLY A 109
GLY A 110
 None
 0.86A 1ekjG-1ethA:
undetectable
1ekjH-1ethA:
undetectable		 1ekjG-1ethA:
18.38
1ekjH-1ethA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 8 PHE A 387
ILE A 372
LEU A 360
VAL A 343
 None
 0.87A 1fslA-1ethA:
undetectable		 1fslA-1ethA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 8 PHE A 387
ILE A 372
LEU A 360
VAL A 343
 None
 0.88A 1fslB-1ethA:
undetectable		 1fslB-1ethA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H1D_A_SAMA301_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 4 SER A 111
GLU A  84
SER A  88
ASP A 106
 None
 1.48A 1h1dA-1ethA:
2.2		 1h1dA-1ethA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 8 ALA A 272
GLY A 309
ILE A 203
ILE A  74
ILE A  90
 None
 1.11A 1hshD-1ethA:
0.0		 1hshD-1ethA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 12 HIS A 148
GLU A  98
ILE A 275
ILE A  90
TYR A 271
 None
 1.12A 1ki7A-1ethA:
0.0		 1ki7A-1ethA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 THR A 256
GLU A  84
ASP A 106
 None
 0.74A 1nt2A-1ethA:
2.4		 1nt2A-1ethA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 THR A  61
THR A  59
PRO A  57
 None
 0.77A 1qfiB-1ethA:
undetectable		 1qfiB-1ethA:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 12 TYR A 271
GLY A 175
ALA A 197
ILE A  75
HIS A 148
 None
 1.03A 1ve3A-1ethA:
undetectable		 1ve3A-1ethA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 12 TYR A 271
GLY A 175
ALA A 197
ILE A  75
HIS A 148
 None
 1.09A 1ve3B-1ethA:
undetectable		 1ve3B-1ethA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 5 SER A 111
GLU A  84
SER A  88
ASP A 106
 None
 1.45A 1vidA-1ethA:
2.2		 1vidA-1ethA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 6 GLY A 309
SER A 274
LEU A 176
ILE A  90
 None
 0.94A 1yajF-1ethA:
9.0		 1yajF-1ethA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 THR A  59
PRO A  57
THR A  61
 None
 0.62A 209dC-1ethA:
undetectable		 209dC-1ethA:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 ASP A  85
ILE A 252
VAL A 260
 None
None
C8E  A 456 ( 4.0A)
 0.54A 2avvD-1ethA:
undetectable		 2avvD-1ethA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 8 LEU A 176
ILE A 203
ILE A  90
ARG A 172
 None
 0.94A 2azxA-1ethA:
2.0		 2azxA-1ethA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 ALA A 416
VAL A 414
TRP A 403
 None
 0.97A 2izqA-1ethA:
undetectable
2izqB-1ethA:
undetectable		 2izqA-1ethA:
3.41
2izqB-1ethA:
3.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KI5_B_AC2B2_1
(PROTEIN (THYMIDINE
KINASE))		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 12 HIS A 148
GLU A  98
ILE A 275
ILE A  90
TYR A 271
 None
 1.19A 2ki5B-1ethA:
0.2		 2ki5B-1ethA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 ASN A  93
LEU A  94
HIS A 310
 None
 0.86A 2q6fB-1ethA:
0.0		 2q6fB-1ethA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 5 SER A 334
ARG A 266
PRO A 236
GLY A 237
 None
 1.22A 2y7kB-1ethA:
0.0		 2y7kB-1ethA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 SER A 334
ASP A 273
ASN A  93
 None
 0.98A 3lsfB-1ethA:
0.0
3lsfE-1ethA:
undetectable		 3lsfB-1ethA:
18.72
3lsfE-1ethA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 ASP A 273
ASN A  93
SER A 334
 None
 0.82A 3lslA-1ethA:
0.1
3lslD-1ethA:
0.0		 3lslA-1ethA:
18.94
3lslD-1ethA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 SER A 334
ASP A 273
ASN A  93
 None
 0.93A 3lslA-1ethA:
0.0
3lslD-1ethA:
0.0		 3lslA-1ethA:
18.94
3lslD-1ethA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 10 VAL A 105
PHE A  39
ILE A  75
ALA A 127
VAL A  35
 None
 0.90A 3me6A-1ethA:
0.0		 3me6A-1ethA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 9 VAL A 105
PHE A  39
ILE A  75
ALA A 127
VAL A  35
 None
 0.89A 3me6C-1ethA:
0.0		 3me6C-1ethA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 9 VAL A 105
PHE A  39
ILE A  75
ALA A 127
VAL A  35
 None
 0.87A 3me6D-1ethA:
0.0		 3me6D-1ethA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		6 / 12 ALA A 272
ASP A 273
GLY A 309
ILE A 203
ILE A  74
ILE A  90
 None
 1.46A 3s54B-1ethA:
undetectable		 3s54B-1ethA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 8 ILE A 103
ILE A  60
PHE A  65
GLU A 134
 None
None
None
NAG  A 450 ( 3.0A)
 0.79A 3ua5A-1ethA:
0.0		 3ua5A-1ethA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 8 PHE A 387
TYR A 341
VAL A 343
ILE A 419
 None
 0.99A 4a97D-1ethA:
0.0		 4a97D-1ethA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 7 PHE A 387
TYR A 341
VAL A 343
ILE A 419
 None
 0.97A 4a97H-1ethA:
0.0		 4a97H-1ethA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 8 PHE A 387
TYR A 341
VAL A 343
ILE A 419
 None
 0.99A 4a97I-1ethA:
0.0		 4a97I-1ethA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 ARG A 112
TRP A 107
GLY A  77
 None
None
C8E  A 456 (-3.2A)
 0.90A 4e7cA-1ethA:
0.0		 4e7cA-1ethA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_C_ACTC506_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 5 ARG A 112
TRP A 107
HIS A  76
GLY A  77
 None
None
None
C8E  A 456 (-3.2A)
 1.16A 4e7cC-1ethA:
0.0		 4e7cC-1ethA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 12 GLY A 163
GLY A 160
LEU A 192
ALA A 130
GLU A 171
 None
CA  A 449 ( 4.7A)
None
None
None
 0.97A 4lg1B-1ethA:
undetectable		 4lg1B-1ethA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 HIS A 152
TRP A 107
SER A 267
 C8E  A 456 (-3.3A)
None
None
 1.21A 4lrhD-1ethA:
0.0		 4lrhD-1ethA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 12 VAL A 437
LEU A 347
GLY A 415
ILE A 419
LEU A 445
 None
 1.25A 4o5fA-1ethA:
undetectable
4o5fB-1ethA:
1.0		 4o5fA-1ethA:
19.21
4o5fB-1ethA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 12 LEU A 445
VAL A 437
LEU A 347
GLY A 415
ILE A 419
 None
 1.26A 4o5fA-1ethA:
undetectable
4o5fB-1ethA:
undetectable		 4o5fA-1ethA:
19.21
4o5fB-1ethA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 6 ILE A 173
GLY A 175
SER A 274
ILE A  90
 None
 0.82A 4r21A-1ethA:
0.0		 4r21A-1ethA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 6 SER A 334
GLY A 255
GLU A 254
ASP A 258
 None
 1.06A 4uckB-1ethA:
undetectable		 4uckB-1ethA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 11 PHE A 281
GLY A 175
LEU A 176
LEU A 225
ALA A 312
 None
 1.15A 4wnuA-1ethA:
0.0		 4wnuA-1ethA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 12 LEU A 445
VAL A 437
LEU A 347
GLY A 415
ILE A 419
 None
 1.25A 5b8hA-1ethA:
1.2
5b8hB-1ethA:
undetectable		 5b8hA-1ethA:
19.39
5b8hB-1ethA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 ASP A 332
ASN A 329
PHE A 387
 None
 0.76A 5dsgB-1ethA:
undetectable		 5dsgB-1ethA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 5 SER A 111
GLU A  84
SER A  88
ASP A 106
 None
 1.48A 5fhrA-1ethA:
2.3		 5fhrA-1ethA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 4 VAL A 393
GLU A 392
GLY A 362
LEU A 396
 None
 1.34A 5g5gC-1ethA:
0.0		 5g5gC-1ethA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 5 HIS A 157
VAL A 149
GLY A 126
ALA A 162
 None
 1.03A 5hwaA-1ethA:
0.0		 5hwaA-1ethA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 5 TYR A  42
GLU A  83
GLY A  82
SER A  88
 None
 1.48A 5jhdJ-1ethA:
1.6		 5jhdJ-1ethA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 ARG A  72
ILE A 103
PHE A  73
 None
 0.73A 5kirA-1ethA:
0.0		 5kirA-1ethA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 9 ASN A 121
ALA A 118
ILE A  79
GLY A  77
ILE A  75
 None
None
C8E  A 456 ( 3.5A)
C8E  A 456 (-3.2A)
None
 1.26A 5kr2A-1ethA:
undetectable		 5kr2A-1ethA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 9 ASN A 121
ALA A 118
ILE A  79
GLY A  77
ILE A  75
 None
None
C8E  A 456 ( 3.5A)
C8E  A 456 (-3.2A)
None
 1.26A 5kr2C-1ethA:
undetectable		 5kr2C-1ethA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 12 ASP A 226
HIS A 224
ARG A 172
ARG A 191
LEU A 192
 None
 1.42A 5nd2B-1ethA:
4.3		 5nd2B-1ethA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		5 / 12 VAL A 322
HIS A 224
ARG A 172
ARG A 191
LEU A 192
 None
 1.38A 5nd2B-1ethA:
4.3		 5nd2B-1ethA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 6 ILE A 170
ILE A 203
HIS A 224
PHE A 281
 None
 0.98A 5vkqB-1ethA:
0.0
5vkqC-1ethA:
0.0		 5vkqB-1ethA:
13.92
5vkqC-1ethA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 6 ILE A 170
ILE A 203
HIS A 224
PHE A 281
 None
 0.97A 5vkqC-1ethA:
0.0
5vkqD-1ethA:
0.0		 5vkqC-1ethA:
13.92
5vkqD-1ethA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 ARG A 165
PHE A 132
LEU A   8
 BMA  A 454 (-3.4A)
None
None
 0.72A 5x1bC-1ethA:
0.5		 5x1bC-1ethA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		4 / 6 GLU A 386
ARG A 340
PHE A 292
VAL A 291
 None
 1.41A 6fgdA-1ethA:
2.9		 6fgdA-1ethA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1eth TRIACYLGLYCEROL
ACYL-HYDROLASE
(Sus
scrofa) 		3 / 3 LYS A  70
SER A 143
SER A 145
 None
 1.12A 6gbfA-1ethA:
3.3		 6gbfA-1ethA:
22.00