SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eu1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.83A 1a7yA-1eu1A:
undetectable		 1a7yA-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.73A 1dscC-1eu1A:
undetectable		 1dscC-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.80A 1fjaC-1eu1A:
undetectable		 1fjaC-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.80A 1fjaD-1eu1A:
undetectable		 1fjaD-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 109
PRO A 106
THR A 107
 None
 0.87A 1i3wE-1eu1A:
undetectable		 1i3wE-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.83A 1i3wF-1eu1A:
undetectable		 1i3wF-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.86A 1i3wG-1eu1A:
undetectable		 1i3wG-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.86A 1i3wH-1eu1A:
undetectable		 1i3wH-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.76A 1mnvD-1eu1A:
undetectable		 1mnvD-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N3Z_A_ADNA126_1
(RIBONUCLEASE,
SEMINAL)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 ALA A 759
ASN A 737
GLN A 440
ALA A 641
VAL A 639
 None
MGD  A1001 (-3.0A)
MGD  A1001 (-4.3A)
MGD  A1001 (-3.6A)
None
 1.47A 1n3zA-1eu1A:
0.0		 1n3zA-1eu1A:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 6 ALA A 508
TYR A 506
ILE A  49
GLU A 480
 None
 1.23A 1oniB-1eu1A:
0.3
1oniC-1eu1A:
0.0		 1oniB-1eu1A:
14.08
1oniC-1eu1A:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 109
PRO A 106
THR A 107
 None
 0.85A 1ovfB-1eu1A:
undetectable		 1ovfB-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.82A 1qfiA-1eu1A:
undetectable		 1qfiA-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 6 LEU A 518
PHE A 515
ALA A 516
LEU A  90
 None
 0.92A 1ukbA-1eu1A:
undetectable		 1ukbA-1eu1A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.81A 1unjL-1eu1A:
undetectable		 1unjL-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.83A 1unjR-1eu1A:
undetectable		 1unjR-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.83A 1unjW-1eu1A:
undetectable		 1unjW-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 109
PRO A 106
THR A 107
 None
 0.85A 1unjX-1eu1A:
undetectable		 1unjX-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.82A 1unjX-1eu1A:
undetectable		 1unjX-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.79A 1unmE-1eu1A:
undetectable		 1unmE-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 109
PRO A 106
THR A 107
 None
 0.82A 1unmF-1eu1A:
undetectable		 1unmF-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 107
THR A 109
PRO A 106
 None
 0.78A 1unmF-1eu1A:
undetectable		 1unmF-1eu1A:
1.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 ASP A 613
TYR A 612
GLU A 331
 None
 0.86A 1vm1A-1eu1A:
0.0		 1vm1A-1eu1A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 7 LEU A  42
PHE A  29
GLY A  44
THR A 655
 None
 1.09A 2bdmA-1eu1A:
undetectable		 2bdmA-1eu1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 THR A 242
LEU A 340
SER A 310
ILE A 296
GLY A 298
 None
 0.84A 3cv9A-1eu1A:
0.0		 3cv9A-1eu1A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 TYR A 204
ASP A  35
HIS A  40
 None
 0.78A 3e23A-1eu1A:
undetectable		 3e23A-1eu1A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 5 ARG A 315
ILE A 344
VAL A 182
THR A 215
 None
 1.19A 3eigA-1eu1A:
0.6		 3eigA-1eu1A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 10 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.18A 3fhjA-1eu1A:
undetectable		 3fhjA-1eu1A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 10 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.17A 3fhjB-1eu1A:
undetectable		 3fhjB-1eu1A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 10 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.18A 3fhjC-1eu1A:
undetectable		 3fhjC-1eu1A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.18A 3fhjD-1eu1A:
undetectable		 3fhjD-1eu1A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 10 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.18A 3fhjE-1eu1A:
undetectable		 3fhjE-1eu1A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.18A 3fhjF-1eu1A:
undetectable		 3fhjF-1eu1A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.23A 3fi0A-1eu1A:
undetectable		 3fi0A-1eu1A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.23A 3fi0C-1eu1A:
undetectable		 3fi0C-1eu1A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.22A 3fi0D-1eu1A:
undetectable		 3fi0D-1eu1A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.21A 3fi0F-1eu1A:
0.6		 3fi0F-1eu1A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.18A 3fi0H-1eu1A:
undetectable		 3fi0H-1eu1A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 8 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.24A 3fi0I-1eu1A:
undetectable		 3fi0I-1eu1A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.20A 3fi0K-1eu1A:
undetectable		 3fi0K-1eu1A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.21A 3fi0M-1eu1A:
undetectable		 3fi0M-1eu1A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.21A 3fi0N-1eu1A:
undetectable		 3fi0N-1eu1A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.21A 3fi0O-1eu1A:
undetectable		 3fi0O-1eu1A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.20A 3fi0R-1eu1A:
undetectable		 3fi0R-1eu1A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 8 THR A 225
GLN A 712
SER A 642
ASN A 192
 MGD  A1002 ( 4.6A)
None
MGD  A1002 (-4.2A)
None
 1.12A 3kp2A-1eu1A:
0.0
3kp2B-1eu1A:
0.0		 3kp2A-1eu1A:
13.81
3kp2B-1eu1A:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 12 ASN A 192
GLY A 363
GLN A 168
MET A 181
LEU A 210
 None
 1.40A 3mneA-1eu1A:
undetectable		 3mneA-1eu1A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 6 ILE A 484
PRO A 119
ASP A  35
GLY A  11
 None
 0.87A 3n3iA-1eu1A:
0.0		 3n3iA-1eu1A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 9 GLY A 716
GLY A 717
TYR A 733
VAL A 773
GLU A 715
 None
None
None
None
MGD  A1001 (-3.9A)
 1.17A 3owxA-1eu1A:
2.4		 3owxA-1eu1A:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 12 ASN A 192
ASP A 200
GLY A 202
ALA A 205
ALA A 209
 None
 1.12A 3p5nB-1eu1A:
undetectable		 3p5nB-1eu1A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 7 VAL A 158
LEU A 748
ASN A 416
MET A 610
ILE A 607
 None
 1.31A 3rfmA-1eu1A:
0.0		 3rfmA-1eu1A:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_B_DXCB92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 5 VAL A  27
VAL A  21
ARG A  20
LYS A 499
 None
 1.47A 3rv5A-1eu1A:
0.0
3rv5B-1eu1A:
0.0		 3rv5A-1eu1A:
8.23
3rv5B-1eu1A:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 6 LEU A 265
HIS A 260
MET A 343
THR A 339
 None
 1.28A 3thrB-1eu1A:
2.7		 3thrB-1eu1A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 ARG A 401
PRO A 423
PHE A 413
 GLC  A2004 (-4.1A)
None
None
 0.72A 3thrC-1eu1A:
0.0		 3thrC-1eu1A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 6 LEU A 722
PRO A 724
GLU A 726
SER A 725
 None
 1.17A 3vlnA-1eu1A:
undetectable		 3vlnA-1eu1A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 12 ASP A 200
HIS A 201
GLY A 364
SER A 365
GLY A  15
 None
 0.93A 4blvB-1eu1A:
undetectable		 4blvB-1eu1A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 7 GLY A 716
GLY A 717
TYR A 733
GLU A 715
 None
None
None
MGD  A1001 (-3.9A)
 1.05A 4fgkB-1eu1A:
undetectable		 4fgkB-1eu1A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 10 ALA A 448
LEU A 406
VAL A 425
ARG A 442
ILE A 397
 None
 0.95A 4j14A-1eu1A:
0.0		 4j14A-1eu1A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 8 ASP A 731
VAL A 689
GLY A 699
VAL A 736
ILE A 696
 None
 1.46A 4ll3A-1eu1A:
1.5		 4ll3A-1eu1A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 ALA A 448
GLN A 440
GLY A 754
 None
MGD  A1001 (-4.3A)
MGD  A1001 (-3.6A)
 0.64A 4odoC-1eu1A:
0.0		 4odoC-1eu1A:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 7 ALA A 420
THR A 419
ALA A 418
MET A 405
 None
 0.65A 4qw0K-1eu1A:
undetectable		 4qw0K-1eu1A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 7 ALA A 420
THR A 419
ALA A 418
MET A 405
 None
 0.65A 4qw0Y-1eu1A:
undetectable		 4qw0Y-1eu1A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 ASP A 261
VAL A 312
LEU A 254
 None
 0.68A 5e5jB-1eu1A:
1.6		 5e5jB-1eu1A:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 12 ASP A 459
LEU A 657
ASP A  47
SER A 118
ARG A 658
 MGD  A1001 (-3.0A)
None
None
MGD  A1001 (-2.7A)
None
 1.30A 5syfB-1eu1A:
2.2		 5syfB-1eu1A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 12 ASN A 192
GLY A 363
GLN A 168
MET A 181
LEU A 210
 None
 1.33A 5uc3A-1eu1A:
undetectable		 5uc3A-1eu1A:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 8 GLY A  15
TRP A  32
VAL A 487
ASP A 200
 None
GLC  A2003 (-4.1A)
None
None
 1.03A 5vlmA-1eu1A:
undetectable		 5vlmA-1eu1A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 5 LEU A 670
THR A 225
PRO A 240
ARG A 239
 None
MGD  A1002 ( 4.6A)
MGD  A1002 (-4.0A)
None
 1.20A 6ew0B-1eu1A:
1.8		 6ew0B-1eu1A:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 5 LEU A 670
THR A 225
PRO A 240
ARG A 239
 None
MGD  A1002 ( 4.6A)
MGD  A1002 (-4.0A)
None
 1.20A 6ew0D-1eu1A:
2.0		 6ew0D-1eu1A:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 5 LEU A 670
THR A 225
PRO A 240
ARG A 239
 None
MGD  A1002 ( 4.6A)
MGD  A1002 (-4.0A)
None
 1.20A 6ew0H-1eu1A:
1.9		 6ew0H-1eu1A:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		4 / 5 LEU A 670
THR A 225
PRO A 240
ARG A 239
 None
MGD  A1002 ( 4.6A)
MGD  A1002 (-4.0A)
None
 1.20A 6ew0I-1eu1A:
1.8		 6ew0I-1eu1A:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		5 / 12 MET A 250
ALA A 251
TYR A 255
PHE A 272
VAL A 338
 None
 1.04A 6hu9N-1eu1A:
0.0		 6hu9N-1eu1A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 1eu1 DIMETHYL SULFOXIDE
REDUCTASE
(Rhodobacter
sphaeroides) 		3 / 3 ILE A 572
THR A 573
PRO A 366
 None
 0.66A 6ncsA-1eu1A:
undetectable		 6ncsA-1eu1A:
16.15