SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1euf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)
1euf DUODENASE
(Bos
taurus)
5 / 8 HIS A  57
SER A 190
SER A 195
VAL A 213
GLY A 216
None
0.69A 1aq7A-1eufA:
35.6
1aq7A-1eufA:
38.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)
1euf DUODENASE
(Bos
taurus)
5 / 12 HIS A  57
LEU A  99
SER A 195
VAL A 213
GLY A 216
None
0.63A 1etrH-1eufA:
32.6
1etrH-1eufA:
33.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
1euf DUODENASE
(Bos
taurus)
4 / 8 SER A 190
SER A 195
VAL A 213
GLY A 216
None
0.24A 1f5lA-1eufA:
32.6
1f5lA-1eufA:
34.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TNL_A_TPAA900_1
(TRYPSIN)
1euf DUODENASE
(Bos
taurus)
4 / 6 SER A 190
SER A 195
VAL A 213
GLY A 216
None
0.38A 1tnlA-1eufA:
35.9
1tnlA-1eufA:
38.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)
1euf DUODENASE
(Bos
taurus)
5 / 12 TYR A 215
ILE A  16
ALA A 183
ASN A 189
PRO A 225
None
1.15A 2okcA-1eufA:
undetectable
2okcA-1eufA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)
1euf DUODENASE
(Bos
taurus)
5 / 12 TYR A 215
ILE A  16
ALA A 183
ASN A 189
PRO A 225
None
1.16A 2okcB-1eufA:
undetectable
2okcB-1eufA:
16.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)
1euf DUODENASE
(Bos
taurus)
4 / 6 SER A 190
SER A 195
VAL A 213
GLY A 216
None
0.27A 2otvA-1eufA:
36.0
2otvA-1eufA:
38.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)
1euf DUODENASE
(Bos
taurus)
6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
LEU A  53
None
1.48A 2oxtD-1eufA:
undetectable
2oxtD-1eufA:
21.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)
1euf DUODENASE
(Bos
taurus)
4 / 8 SER A 190
SER A 195
VAL A 213
GLY A 216
None
0.37A 2vinA-1eufA:
12.5
2vinA-1eufA:
34.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)
1euf DUODENASE
(Bos
taurus)
5 / 12 ILE A 121
GLY A  44
GLY A 197
ASP A 194
TYR A  29
None
1.25A 2zw9A-1eufA:
undetectable
2zw9A-1eufA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1euf DUODENASE
(Bos
taurus)
3 / 3 GLY A 197
GLY A 193
GLY A  43
None
0.38A 3bogC-1eufA:
0.0
3bogC-1eufA:
13.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)
1euf DUODENASE
(Bos
taurus)
5 / 11 HIS A  57
LEU A  99
SER A 190
SER A 195
GLY A 216
None
0.54A 3gy3A-1eufA:
16.7
3gy3A-1eufA:
38.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)
1euf DUODENASE
(Bos
taurus)
5 / 12 LEU A 106
GLY A  43
GLY A  44
SER A 190
ASP A 102
None
1.21A 3i5uB-1eufA:
undetectable
3i5uB-1eufA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)
1euf DUODENASE
(Bos
taurus)
5 / 10 LEU A  53
ILE A 231
PRO A 124
SER A 126
SER A 236
None
None
None
PO4  A 600 (-2.5A)
None
1.41A 3ijxB-1eufA:
undetectable
3ijxD-1eufA:
undetectable
3ijxB-1eufA:
21.01
3ijxD-1eufA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_D_HCZD800_1
(GLUTAMATE RECEPTOR 2)
1euf DUODENASE
(Bos
taurus)
5 / 9 ILE A 231
PRO A 124
SER A 126
SER A 236
LEU A  53
None
None
PO4  A 600 (-2.5A)
None
None
1.28A 3ijxB-1eufA:
undetectable
3ijxD-1eufA:
0.0
3ijxB-1eufA:
21.01
3ijxD-1eufA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)
1euf DUODENASE
(Bos
taurus)
5 / 10 LEU A  53
ILE A 231
PRO A 124
SER A 126
SER A 236
None
None
None
PO4  A 600 (-2.5A)
None
1.36A 3ik6B-1eufA:
undetectable
3ik6E-1eufA:
undetectable
3ik6B-1eufA:
21.01
3ik6E-1eufA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)
1euf DUODENASE
(Bos
taurus)
5 / 10 LEU A  53
ILE A 231
PRO A 124
SER A 126
SER A 236
None
None
None
PO4  A 600 (-2.5A)
None
1.41A 3iluB-1eufA:
0.0
3iluE-1eufA:
0.0
3iluB-1eufA:
21.01
3iluE-1eufA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)
1euf DUODENASE
(Bos
taurus)
5 / 11 ILE A 231
PRO A 124
SER A 126
SER A 236
LEU A  53
None
None
PO4  A 600 (-2.5A)
None
None
1.36A 3iluB-1eufA:
0.0
3iluE-1eufA:
0.0
3iluB-1eufA:
21.01
3iluE-1eufA:
21.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)
1euf DUODENASE
(Bos
taurus)
4 / 6 SER A 190
SER A 195
VAL A 213
GLY A 216
None
0.39A 3rxfA-1eufA:
13.2
3rxfA-1eufA:
38.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)
1euf DUODENASE
(Bos
taurus)
5 / 12 ARG A  27
GLY A 140
ASP A 194
PHE A 191
ASN A 189
None
1.33A 3t7sA-1eufA:
undetectable
3t7sA-1eufA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)
1euf DUODENASE
(Bos
taurus)
5 / 12 ARG A  27
GLY A 140
ASP A 194
PHE A 191
ASN A 189
None
1.34A 3t7sB-1eufA:
undetectable
3t7sB-1eufA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)
1euf DUODENASE
(Bos
taurus)
5 / 12 ARG A  27
GLY A 140
ASP A 194
PHE A 191
ASN A 189
None
1.36A 3t7sD-1eufA:
undetectable
3t7sD-1eufA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJQ_A_27RA401_1
(DNA POLYMERASE III
SUBUNIT BETA)
1euf DUODENASE
(Bos
taurus)
4 / 5 ARG A  27
TYR A  29
PRO A 198
VAL A 213
None
1.48A 4mjqA-1eufA:
0.2
4mjqA-1eufA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
1euf DUODENASE
(Bos
taurus)
3 / 3 ILE A  17
ASP A 226
ARG A 187
None
0.84A 4pstA-1eufA:
undetectable
4pstA-1eufA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)
1euf DUODENASE
(Bos
taurus)
6 / 12 GLY A 142
GLY A  44
GLY A 196
GLY A 193
THR A  54
VAL A  52
None
1.29A 5eiwC-1eufA:
undetectable
5eiwC-1eufA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)
1euf DUODENASE
(Bos
taurus)
5 / 12 GLY A 197
PRO A 198
VAL A 138
PHE A  45
LEU A  53
None
1.15A 5jo9A-1eufA:
undetectable
5jo9A-1eufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)
1euf DUODENASE
(Bos
taurus)
5 / 9 SER A  38
PHE A  32
SER A 195
GLY A  43
THR A 152
NAG  A 500 ( 4.5A)
None
None
None
None
1.47A 6awpA-1eufA:
undetectable
6awpA-1eufA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)
1euf DUODENASE
(Bos
taurus)
4 / 8 GLY A 216
GLY A 193
SER A 195
ALA A  55
None
0.80A 6hu9H-1eufA:
undetectable
6hu9e-1eufA:
undetectable
6hu9H-1eufA:
15.11
6hu9e-1eufA:
17.45