SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 1eun KDPG ALDOLASE
(Escherichia
coli) 		5 / 9 ALA A  67
VAL A  64
LEU A  44
ILE A  57
ALA A  33
 None
 0.99A 2z0yA-1eunA:
3.0		 2z0yA-1eunA:
27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 1eun KDPG ALDOLASE
(Escherichia
coli) 		4 / 5 ILE A 149
THR A 117
SER A 116
PHE A 134
 None
 1.19A 3snfA-1eunA:
0.0		 3snfA-1eunA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1eun KDPG ALDOLASE
(Escherichia
coli) 		5 / 12 GLU A 120
LEU A 129
PHE A 158
PHE A 134
ILE A 112
 None
 1.21A 4hytA-1eunA:
undetectable		 4hytA-1eunA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 1eun KDPG ALDOLASE
(Escherichia
coli) 		5 / 12 ILE A  57
GLY A  87
ALA A  88
GLU A  85
GLU A  82
 None
 1.33A 4xt8A-1eunA:
undetectable		 4xt8A-1eunA:
24.18