SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1euz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 9 VAL A  96
LEU A 373
VAL A 348
GLY A 346
ALA A 345
 None
None
SO4  A 601 (-3.8A)
None
None
 1.23A 1pxxB-1euzA:
0.0		 1pxxB-1euzA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 10 VAL A  96
LEU A 373
VAL A 348
GLY A 346
ALA A 345
 None
None
SO4  A 601 (-3.8A)
None
None
 1.25A 1pxxD-1euzA:
undetectable		 1pxxD-1euzA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		3 / 3 ALA A  77
VAL A 110
TRP A  74
 None
 0.69A 1tkqA-1euzA:
undetectable		 1tkqA-1euzA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 10 LEU A 230
ALA A 195
ILE A 196
VAL A 217
ALA A 216
 None
 1.19A 1xp0A-1euzA:
0.0		 1xp0A-1euzA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_B_CHDB2_0
(LIVER
CARBOXYLESTERASE 1)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		3 / 3 TRP A 355
LYS A 177
PRO A 137
 None
 1.48A 2dqyB-1euzA:
4.2		 2dqyB-1euzA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 10 MET A 237
LEU A 235
ILE A 199
PRO A 257
GLY A 224
 None
 1.37A 3hcpB-1euzA:
0.4		 3hcpB-1euzA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 12 THR A 227
THR A 191
ALA A 195
GLY A 221
ALA A 295
 None
SO4  A 602 (-2.8A)
None
None
None
 1.05A 3mg02-1euzA:
undetectable
3mg0V-1euzA:
undetectable		 3mg02-1euzA:
18.03
3mg0V-1euzA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 11 THR A 227
THR A 191
ALA A 195
GLY A 221
ALA A 295
 None
SO4  A 602 (-2.8A)
None
None
None
 1.07A 3mg0N-1euzA:
undetectable		 3mg0N-1euzA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 6 VAL A 322
VAL A 289
ILE A 309
MET A 395
 None
 0.97A 3mssD-1euzA:
undetectable		 3mssD-1euzA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 12 VAL A 402
ILE A 313
ILE A 338
LEU A 342
VAL A  96
 None
 1.26A 3w68C-1euzA:
0.0		 3w68C-1euzA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 12 VAL A  96
LEU A 373
VAL A 348
GLY A 346
ALA A 345
 None
None
SO4  A 601 (-3.8A)
None
None
 1.15A 4coxA-1euzA:
0.7		 4coxA-1euzA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 7 ALA A 241
ILE A 249
GLY A 248
ILE A 279
 None
 0.55A 4eatA-1euzA:
4.2		 4eatA-1euzA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 12 THR A 227
THR A 191
ALA A 195
GLY A 221
ALA A 295
 None
SO4  A 602 (-2.8A)
None
None
None
 1.10A 4qvnV-1euzA:
undetectable
4qvnb-1euzA:
undetectable		 4qvnV-1euzA:
20.09
4qvnb-1euzA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 12 THR A 227
THR A 191
ALA A 195
GLY A 221
ALA A 295
 None
SO4  A 602 (-2.8A)
None
None
None
 1.11A 4qvnH-1euzA:
undetectable
4qvnN-1euzA:
undetectable		 4qvnH-1euzA:
20.09
4qvnN-1euzA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		3 / 3 TYR A 160
GLY A 136
PRO A 137
 None
 0.52A 4qwpA-1euzA:
0.0		 4qwpA-1euzA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 6 ALA A 195
GLY A 224
ILE A 199
VAL A 239
 None
 0.82A 4r21A-1euzA:
undetectable		 4r21A-1euzA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 7 GLU A 366
TYR A 226
GLY A 188
GLY A 186
 None
 0.75A 4rdxA-1euzA:
undetectable		 4rdxA-1euzA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 11 GLY A  70
ILE A 359
ASN A 358
ASP A 140
PRO A  67
 SO4  A 601 (-3.3A)
None
None
None
None
 1.12A 4rtrA-1euzA:
undetectable		 4rtrA-1euzA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 12 GLY A  70
ILE A 359
ASN A 358
ASP A 140
PRO A  67
 SO4  A 601 (-3.3A)
None
None
None
None
 1.13A 4rtsA-1euzA:
1.0		 4rtsA-1euzA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 6 ARG A  16
ARG A 331
ASP A 397
ASP A 328
 None
SO4  A 603 (-4.5A)
None
None
 1.22A 4xqeA-1euzA:
2.2		 4xqeA-1euzA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 6 ARG A  16
ARG A 331
ASP A 397
ASP A 328
 None
SO4  A 603 (-4.5A)
None
None
 1.25A 4xqeB-1euzA:
2.3		 4xqeB-1euzA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 8 ARG A  16
ARG A 331
ASP A 397
ASP A 327
ASP A 328
 None
SO4  A 603 (-4.5A)
None
None
None
 1.19A 4xqgA-1euzA:
2.3		 4xqgA-1euzA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 8 ARG A  16
ARG A 331
ASP A 397
ASP A 327
ASP A 328
 None
SO4  A 603 (-4.5A)
None
None
None
 1.19A 4xqgB-1euzA:
2.4		 4xqgB-1euzA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 12 VAL A  96
LEU A 373
VAL A 348
GLY A 346
ALA A 345
 None
None
SO4  A 601 (-3.8A)
None
None
 1.12A 5ikqB-1euzA:
0.4		 5ikqB-1euzA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 12 VAL A  96
LEU A 373
VAL A 348
GLY A 346
ALA A 345
 None
None
SO4  A 601 (-3.8A)
None
None
 1.13A 5iktA-1euzA:
undetectable		 5iktA-1euzA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 12 GLY A 194
ASN A 344
LEU A 342
ALA A 380
LYS A  93
 None
 1.20A 5kc4E-1euzA:
1.2		 5kc4E-1euzA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 10 THR A 198
ALA A 380
ALA A 195
GLY A 194
ALA A 345
 None
 1.08A 5lf3H-1euzA:
undetectable
5lf3I-1euzA:
undetectable		 5lf3H-1euzA:
20.14
5lf3I-1euzA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 10 THR A 198
ALA A 380
ALA A 195
GLY A 194
ALA A 345
 None
 1.08A 5lf3V-1euzA:
undetectable
5lf3W-1euzA:
undetectable		 5lf3V-1euzA:
20.14
5lf3W-1euzA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 12 THR A 227
THR A 191
ALA A 195
GLY A 221
ALA A 295
 None
SO4  A 602 (-2.8A)
None
None
None
 1.06A 5lf7V-1euzA:
undetectable
5lf7b-1euzA:
undetectable		 5lf7V-1euzA:
20.14
5lf7b-1euzA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 11 THR A 198
ALA A 380
ALA A 195
GLY A 194
ALA A 345
 None
 1.09A 5lf7H-1euzA:
undetectable
5lf7I-1euzA:
undetectable		 5lf7H-1euzA:
20.14
5lf7I-1euzA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 12 THR A 227
THR A 191
ALA A 195
GLY A 221
ALA A 295
 None
SO4  A 602 (-2.8A)
None
None
None
 1.06A 5lf7H-1euzA:
undetectable
5lf7N-1euzA:
undetectable		 5lf7H-1euzA:
20.14
5lf7N-1euzA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 11 THR A 198
ALA A 380
ALA A 195
GLY A 194
ALA A 345
 None
 1.09A 5lf7V-1euzA:
undetectable
5lf7W-1euzA:
undetectable		 5lf7V-1euzA:
20.14
5lf7W-1euzA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 9 ILE A 338
VAL A 291
GLU A 201
LEU A 235
ILE A 196
 None
 1.09A 5mzpA-1euzA:
undetectable		 5mzpA-1euzA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 8 VAL A 317
ILE A 196
ILE A 199
ILE A 215
SER A 243
 None
 1.06A 5numA-1euzA:
undetectable		 5numA-1euzA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 7 ILE A 309
LEU A 285
ILE A 199
ALA A 296
 None
 0.84A 6b5vA-1euzA:
0.0
6b5vC-1euzA:
0.0		 6b5vA-1euzA:
10.50
6b5vC-1euzA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 7 ILE A 309
LEU A 285
ILE A 338
ALA A 296
 None
 0.73A 6b5vA-1euzA:
0.0
6b5vC-1euzA:
0.0		 6b5vA-1euzA:
10.50
6b5vC-1euzA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 7 ALA A 296
ILE A 309
LEU A 285
ILE A 199
 None
 0.82A 6b5vA-1euzA:
0.0
6b5vB-1euzA:
0.0		 6b5vA-1euzA:
10.50
6b5vB-1euzA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 7 ALA A 296
ILE A 309
LEU A 285
ILE A 338
 None
 0.72A 6b5vA-1euzA:
0.0
6b5vB-1euzA:
0.0		 6b5vA-1euzA:
10.50
6b5vB-1euzA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 7 ILE A 309
LEU A 285
ILE A 199
ALA A 296
 None
 0.84A 6b5vC-1euzA:
0.0
6b5vD-1euzA:
0.0		 6b5vC-1euzA:
10.50
6b5vD-1euzA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 7 ILE A 309
LEU A 285
ILE A 338
ALA A 296
 None
 0.74A 6b5vC-1euzA:
0.0
6b5vD-1euzA:
0.0		 6b5vC-1euzA:
10.50
6b5vD-1euzA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 7 ALA A 296
ILE A 309
LEU A 285
ILE A 199
 None
 0.84A 6b5vB-1euzA:
0.0
6b5vD-1euzA:
0.0		 6b5vB-1euzA:
10.50
6b5vD-1euzA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 7 ALA A 296
ILE A 309
LEU A 285
ILE A 338
 None
 0.73A 6b5vB-1euzA:
0.0
6b5vD-1euzA:
0.0		 6b5vB-1euzA:
10.50
6b5vD-1euzA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		5 / 12 GLY A  71
PRO A 321
VAL A  59
GLU A  78
GLY A 107
 SO4  A 601 ( 4.7A)
None
None
None
None
 1.33A 6gngA-1euzA:
undetectable		 6gngA-1euzA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 1euz GLUTAMATE
DEHYDROGENASE
(Thermococcus
profundus) 		4 / 8 ALA A 241
GLY A 254
LEU A 255
ALA A 276
 None
 0.76A 6mdqA-1euzA:
undetectable		 6mdqA-1euzA:
10.36