SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ev1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 1ev1 ECHOVIRUS 1
ECHOVIRUS 1
(Enterovirus
B;
Enterovirus
B) 		5 / 12 PRO 1  44
GLY 3 113
ILE 3 169
VAL 3 223
SER 3 222
 None
 1.17A 1sg9A-1ev11:
undetectable		 1sg9A-1ev11:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 8 PRO 2  56
LEU 2  91
GLY 2  90
PRO 2 247
 None
 0.93A 1ya4A-1ev12:
undetectable		 1ya4A-1ev12:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 1ev1 ECHOVIRUS 1
ECHOVIRUS 1
(Enterovirus
B;
Enterovirus
B) 		3 / 3 SER 1  62
GLU 3  48
ASP 3 220
 None
 0.76A 2avdB-1ev11:
undetectable		 2avdB-1ev11:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 8 LEU 1 219
TYR 1 146
ILE 1 119
ILE 1  95
 None
PLM  1   0 (-3.7A)
None
PLM  1   0 ( 4.6A)
 0.75A 2bu8A-1ev11:
undetectable		 2bu8A-1ev11:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1ev1 ECHOVIRUS 1
ECHOVIRUS 1
(Enterovirus
B;
Enterovirus
B) 		4 / 7 ASP 3  17
ARG 1 180
ASP 3  18
ALA 1  69
 None
 1.28A 2e5dA-1ev13:
undetectable
2e5dB-1ev13:
undetectable		 2e5dA-1ev13:
16.40
2e5dB-1ev13:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		3 / 3 ASN 1 167
TYR 1 160
SER 1 165
 None
 0.90A 2gvcE-1ev11:
undetectable		 2gvcE-1ev11:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 6 LEU 1 219
TYR 1 146
ILE 1 119
ILE 1  95
 None
PLM  1   0 (-3.7A)
None
PLM  1   0 ( 4.6A)
 0.70A 2q8hA-1ev11:
undetectable		 2q8hA-1ev11:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		3 / 3 SER 3  94
THR 3  99
PHE 3 221
 None
 0.66A 2x91A-1ev13:
0.0		 2x91A-1ev13:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 1ev1 ECHOVIRUS 1
ECHOVIRUS 1
(Enterovirus
B;
Enterovirus
B) 		3 / 3 GLU 1  65
ASP 3  18
ASP 1 116
 None
 0.74A 3jb2A-1ev11:
undetectable		 3jb2A-1ev11:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 1ev1 ECHOVIRUS 1
ECHOVIRUS 1
(Enterovirus
B;
Enterovirus
B) 		3 / 3 TRP 2 189
ALA 2  29
VAL 1  34
 None
 1.02A 3l8lA-1ev12:
undetectable
3l8lB-1ev12:
undetectable		 3l8lA-1ev12:
4.80
3l8lB-1ev12:
4.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		3 / 3 PRO 2  53
THR 2  54
LEU 2 255
 None
 0.52A 3ttrA-1ev12:
0.0		 3ttrA-1ev12:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 7 THR 2 199
LEU 2  18
VAL 2  33
VAL 2  31
 None
 0.97A 4cp4A-1ev12:
0.0		 4cp4A-1ev12:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		3 / 3 PHE 2 226
VAL 2 110
ILE 2 241
 None
 0.55A 4emaA-1ev12:
undetectable		 4emaA-1ev12:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 8 GLN 3  82
GLY 3  85
THR 3 192
THR 1 281
 None
 0.96A 4k87A-1ev13:
undetectable		 4k87A-1ev13:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 7 SER 3  94
GLN 3  87
PHE 3  86
ASN 3  97
 None
 1.21A 4kcnB-1ev13:
undetectable		 4kcnB-1ev13:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRA_C_CPFC401_1
(OUTER MEMBRANE
PROTEIN F)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		5 / 9 ARG 1 254
TYR 1 258
ARG 1 104
GLY 1 209
THR 1 211
 None
 1.18A 4kraC-1ev11:
0.0		 4kraC-1ev11:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		3 / 3 ASP 1 159
TYR 1 160
TRP 1 162
 None
 1.22A 4p7nA-1ev11:
undetectable		 4p7nA-1ev11:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		3 / 3 PRO 2 203
MET 2 202
TYR 2  35
 None
 1.03A 4qa0B-1ev12:
0.0		 4qa0B-1ev12:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		3 / 3 PRO 2 203
MET 2 202
TYR 2  35
 None
 1.00A 4qa0A-1ev12:
undetectable		 4qa0A-1ev12:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		3 / 3 PRO 2 203
MET 2 202
TYR 2  35
 None
 1.05A 4qa2B-1ev12:
undetectable		 4qa2B-1ev12:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 8 PHE 1 115
ASP 3  18
ASP 3  17
TYR 1 239
 None
 1.20A 4qb9D-1ev11:
undetectable		 4qb9D-1ev11:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2G_B_CTCB222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 1ev1 ECHOVIRUS 1
ECHOVIRUS 1
ECHOVIRUS 1
(Enterovirus
B;
Enterovirus
B;
Enterovirus
B) 		5 / 12 HIS 2 216
PRO 2 128
VAL 1 249
ILE 3  36
SER 2 207
 None
 1.50A 4v2gB-1ev12:
undetectable		 4v2gB-1ev12:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		3 / 3 ASP 2  57
LEU 2  18
GLY 2  19
 None
 0.41A 4xmfA-1ev12:
0.0		 4xmfA-1ev12:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		3 / 3 ALA 2 246
TYR 2  64
PRO 2  56
 None
 0.69A 4zdyA-1ev12:
undetectable		 4zdyA-1ev12:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 4 VAL 2 110
ALA 2 198
ASN 2 195
GLN 2 188
 None
 1.44A 4zgfA-1ev12:
undetectable		 4zgfA-1ev12:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 4 ASN 1 214
ILE 1 259
TYR 1 258
PHE 3 237
 PLM  1   0 (-3.5A)
None
None
None
 1.20A 5igvA-1ev11:
0.0		 5igvA-1ev11:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 1ev1 ECHOVIRUS 1
ECHOVIRUS 1
(Enterovirus
B;
Enterovirus
B) 		4 / 8 GLY 2 133
ILE 2 146
TRP 2  79
ASP 1 197
 None
 0.92A 5vlmD-1ev12:
undetectable		 5vlmD-1ev12:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 8 SER 3  94
GLN 3  87
PHE 3  86
ASN 3  97
 None
 1.20A 5vunA-1ev13:
undetectable		 5vunA-1ev13:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 8 SER 3  94
GLN 3  87
PHE 3  86
ASN 3  97
 None
 1.16A 5vunB-1ev13:
0.0		 5vunB-1ev13:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 8 SER 3  94
GLN 3  87
PHE 3  86
ASN 3  97
 None
 1.16A 5vuoB-1ev13:
undetectable		 5vuoB-1ev13:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 8 ASN 1 134
SER 1 132
GLN 1 133
ALA 1 230
 None
 0.80A 5xu8A-1ev11:
undetectable		 5xu8A-1ev11:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 4 PHE 2 185
LEU 3  43
LEU 3 100
VAL 3  40
 None
 1.29A 5xxiA-1ev12:
0.0		 5xxiA-1ev12:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		5 / 12 THR 3  81
GLN 3  82
THR 3 192
VAL 3 191
VAL 3  71
 None
 1.12A 6bzoC-1ev13:
0.0		 6bzoC-1ev13:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 1ev1 ECHOVIRUS 1
ECHOVIRUS 1
(Enterovirus
B;
Enterovirus
B) 		4 / 6 ASN 3 219
VAL 1  43
VAL 1  18
THR 1  17
 None
 1.06A 6f32B-1ev13:
undetectable		 6f32B-1ev13:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 6 GLY 3 102
LEU 3 105
PHE 3  86
PHE 3  84
 None
 0.81A 6h7lA-1ev13:
undetectable		 6h7lA-1ev13:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1ev1 ECHOVIRUS 1
(Enterovirus
B) 		4 / 6 GLY 3 102
LEU 3 105
PHE 3  86
PHE 3  84
 None
 0.81A 6h7lB-1ev13:
undetectable		 6h7lB-1ev13:
20.65