SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ew3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 1ew3 ALLERGEN EQU C 1
(Equus
caballus) 		4 / 7 TYR A  75
ILE A  33
GLU A 137
LEU A 101
 None
 0.98A 1j96B-1ew3A:
undetectable		 1j96B-1ew3A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 1ew3 ALLERGEN EQU C 1
(Equus
caballus) 		5 / 12 ILE A  25
ILE A 156
PHE A 136
ALA A 140
ARG A 141
 None
 1.18A 2j0dA-1ew3A:
undetectable		 2j0dA-1ew3A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1ew3 ALLERGEN EQU C 1
(Equus
caballus) 		4 / 5 TYR A 103
GLY A  54
GLU A 137
VAL A 157
 None
 1.15A 4nkvD-1ew3A:
undetectable		 4nkvD-1ew3A:
17.21