SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eww'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 1eww ANTIFREEZE PROTEIN
(Choristoneura
fumiferana) 		3 / 3 PHE A  42
SER A  50
SER A  52
 None
 0.73A 3ufgB-1ewwA:
0.0		 3ufgB-1ewwA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 1eww ANTIFREEZE PROTEIN
(Choristoneura
fumiferana) 		4 / 8 SER A  50
THR A  35
THR A  48
ILE A  57
 None
 0.99A 5jhdE-1ewwA:
undetectable
5jhdG-1ewwA:
undetectable		 5jhdE-1ewwA:
15.48
5jhdG-1ewwA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1eww ANTIFREEZE PROTEIN
(Choristoneura
fumiferana) 		5 / 10 PHE A  87
SER A  55
GLY A  71
ILE A  68
ALA A  75
 None
 1.13A 5zjiA-1ewwA:
undetectable
5zjiJ-1ewwA:
undetectable		 5zjiA-1ewwA:
22.55
5zjiJ-1ewwA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 1eww ANTIFREEZE PROTEIN
(Choristoneura
fumiferana) 		5 / 12 GLY A  44
VAL A  45
THR A  53
GLY A  54
GLY A  71
 None
 1.04A 6brdB-1ewwA:
undetectable		 6brdB-1ewwA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1eww ANTIFREEZE PROTEIN
(Choristoneura
fumiferana) 		5 / 10 PHE A  87
SER A  52
GLY A  54
ILE A  82
ILE A  64
 None
 1.02A 6ebpD-1ewwA:
undetectable		 6ebpD-1ewwA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1eww ANTIFREEZE PROTEIN
(Choristoneura
fumiferana) 		5 / 11 PHE A  87
SER A  52
GLY A  54
ILE A  82
ILE A  64
 None
 1.01A 6ebzA-1ewwA:
undetectable		 6ebzA-1ewwA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1eww ANTIFREEZE PROTEIN
(Choristoneura
fumiferana) 		5 / 11 PHE A  87
SER A  52
GLY A  54
ILE A  82
ILE A  64
 None
 1.01A 6ebzB-1ewwA:
undetectable		 6ebzB-1ewwA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1eww ANTIFREEZE PROTEIN
(Choristoneura
fumiferana) 		5 / 11 PHE A  87
SER A  52
GLY A  54
ILE A  82
ILE A  64
 None
 1.01A 6ebzD-1ewwA:
undetectable		 6ebzD-1ewwA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1eww ANTIFREEZE PROTEIN
(Choristoneura
fumiferana) 		5 / 11 PHE A  87
SER A  52
GLY A  54
ILE A  82
ILE A  64
 None
 0.99A 6gp2A-1ewwA:
undetectable		 6gp2A-1ewwA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1eww ANTIFREEZE PROTEIN
(Choristoneura
fumiferana) 		5 / 11 PHE A  87
SER A  52
GLY A  54
ILE A  82
ILE A  64
 None
 0.95A 6gp2B-1ewwA:
undetectable		 6gp2B-1ewwA:
16.13