SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ex9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 111
VAL A 242
ALA A 167
ASN A 171
PRO A 179
 None
 1.08A 1dfoA-1ex9A:
1.5		 1dfoA-1ex9A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 111
VAL A 242
ALA A 167
ASN A 171
PRO A 179
 None
 1.07A 1dfoB-1ex9A:
1.6		 1dfoB-1ex9A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 111
VAL A 242
ALA A 167
ASN A 171
PRO A 179
 None
 1.09A 1dfoC-1ex9A:
1.5		 1dfoC-1ex9A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 111
VAL A 242
ALA A 167
ASN A 171
PRO A 179
 None
 1.08A 1dfoD-1ex9A:
1.5		 1dfoD-1ex9A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 142
MET A  16
GLY A 139
LEU A  50
 None
OCP  A 382 (-4.1A)
None
None
 0.63A 1dzmA-1ex9A:
undetectable		 1dzmA-1ex9A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 111
VAL A 242
ALA A 167
ASN A 171
PRO A 179
 None
 1.09A 1eqbA-1ex9A:
1.5		 1eqbA-1ex9A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 111
VAL A 242
ALA A 167
ASN A 171
PRO A 179
 None
 1.08A 1eqbB-1ex9A:
1.5		 1eqbB-1ex9A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 111
VAL A 242
ALA A 167
ASN A 171
PRO A 179
 None
 1.09A 1eqbC-1ex9A:
1.6		 1eqbC-1ex9A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 111
VAL A 242
ALA A 167
ASN A 171
PRO A 179
 None
 1.08A 1eqbD-1ex9A:
1.5		 1eqbD-1ex9A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 ASN A 136
LEU A 138
GLY A 139
MET A  16
LEU A 156
 None
None
None
OCP  A 382 (-4.1A)
None
 0.94A 1gs4A-1ex9A:
undetectable		 1gs4A-1ex9A:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 177
ALA A 102
HIS A 238
SER A 104
 None
 0.91A 1gtfL-1ex9A:
undetectable
1gtfM-1ex9A:
undetectable		 1gtfL-1ex9A:
15.66
1gtfM-1ex9A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 ARG A 274
ASN A 278
ASP A  38
LYS A   1
 None
 1.06A 1hwiB-1ex9A:
undetectable		 1hwiB-1ex9A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 7 ARG A 274
ASN A 278
ASP A  38
LYS A   1
 None
 1.00A 1hwiC-1ex9A:
0.0		 1hwiC-1ex9A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 7 ARG A 274
ASN A 278
ASP A  38
LYS A   1
 None
 1.01A 1hwiD-1ex9A:
0.0		 1hwiD-1ex9A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 ARG A 274
ASN A 278
ASP A  38
LYS A   1
 None
 1.04A 1hwkA-1ex9A:
0.0		 1hwkA-1ex9A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 ARG A 274
ASN A 278
ASP A  38
LYS A   1
 None
 1.05A 1hwkC-1ex9A:
0.0		 1hwkC-1ex9A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 ARG A 274
ASN A 278
ASP A  38
LYS A   1
 None
 1.05A 1hwkD-1ex9A:
0.0		 1hwkD-1ex9A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 162
ASN A 163
LEU A 131
ILE A 121
 OCP  A 382 ( 4.4A)
None
None
None
 1.02A 1z95A-1ex9A:
0.0		 1z95A-1ex9A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		3 / 3 ASP A  26
ILE A  10
VAL A 105
 None
 0.68A 2avvD-1ex9A:
undetectable		 2avvD-1ex9A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 111
VAL A 242
ALA A 167
ASN A 171
PRO A 179
 None
 1.02A 2vmyB-1ex9A:
undetectable		 2vmyB-1ex9A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 111
VAL A 242
ALA A 167
ASN A 171
SER A 181
 None
 1.25A 2vmyB-1ex9A:
undetectable		 2vmyB-1ex9A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 THR A 103
TYR A 196
ILE A 243
SER A 101
 None
 1.05A 2xytE-1ex9A:
undetectable		 2xytE-1ex9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 THR A 103
TYR A 196
ILE A 243
SER A 101
 None
 1.01A 2xytH-1ex9A:
undetectable		 2xytH-1ex9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 7 THR A 103
TYR A 196
ILE A 243
SER A 101
 None
 1.00A 2xytI-1ex9A:
undetectable		 2xytI-1ex9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 145
ALA A 140
ILE A 142
SER A 137
LEU A 138
 None
 1.23A 3gyqB-1ex9A:
2.2		 3gyqB-1ex9A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 10 THR A 180
SER A 181
VAL A 242
GLY A 186
GLY A 240
 None
 1.27A 3ixlA-1ex9A:
2.8		 3ixlA-1ex9A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 6 THR A 103
TYR A 196
ILE A 243
SER A 101
 None
 1.18A 3peoG-1ex9A:
undetectable		 3peoG-1ex9A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		3 / 3 THR A  87
SER A  53
ARG A  56
 None
 0.78A 3phnA-1ex9A:
undetectable		 3phnA-1ex9A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  31
LEU A  35
ALA A  13
THR A  45
VAL A  42
 None
 0.74A 3rukA-1ex9A:
undetectable		 3rukA-1ex9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 8 GLY A  15
GLY A  84
SER A  82
GLY A 106
VAL A 232
 OCP  A 382 (-3.5A)
None
OCP  A 382 (-1.5A)
None
None
 1.38A 3v1nA-1ex9A:
13.9		 3v1nA-1ex9A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 156
GLY A 157
GLU A 160
MET A  16
 None
None
None
OCP  A 382 (-4.1A)
 0.86A 4rjdA-1ex9A:
undetectable
4rjdB-1ex9A:
undetectable		 4rjdA-1ex9A:
14.66
4rjdB-1ex9A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 156
GLY A 157
GLU A 165
ALA A 167
 None
 0.90A 4rjdA-1ex9A:
undetectable
4rjdB-1ex9A:
undetectable		 4rjdA-1ex9A:
14.66
4rjdB-1ex9A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 5 SER A  82
ALA A 107
HIS A 251
LEU A 162
 OCP  A 382 (-1.5A)
None
OCP  A 382 (-3.9A)
OCP  A 382 ( 4.4A)
 1.25A 5dzkf-1ex9A:
0.5
5dzkt-1ex9A:
undetectable		 5dzkf-1ex9A:
23.79
5dzkt-1ex9A:
0.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 SER A 104
GLY A 177
ALA A 102
HIS A 238
 None
 0.87A 5eezL-1ex9A:
undetectable
5eezV-1ex9A:
undetectable		 5eezL-1ex9A:
15.66
5eezV-1ex9A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 SER A 104
GLY A 177
ALA A 102
HIS A 238
 None
 0.87A 5ef1L-1ex9A:
undetectable
5ef1V-1ex9A:
undetectable		 5ef1L-1ex9A:
15.66
5ef1V-1ex9A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 SER A 104
GLY A 177
ALA A 102
HIS A 238
 None
 0.87A 5ef2L-1ex9A:
undetectable
5ef2V-1ex9A:
undetectable		 5ef2L-1ex9A:
15.66
5ef2V-1ex9A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 SER A 211
HIS A 251
LEU A 252
SER A  82
 CA  A 286 ( 4.5A)
OCP  A 382 (-3.9A)
None
OCP  A 382 (-1.5A)
 0.95A 5m8rB-1ex9A:
undetectable		 5m8rB-1ex9A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 SER A 211
HIS A 251
LEU A 252
SER A  82
 CA  A 286 ( 4.5A)
OCP  A 382 (-3.9A)
None
OCP  A 382 (-1.5A)
 0.99A 5m8rD-1ex9A:
0.0		 5m8rD-1ex9A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  42
ILE A  99
LEU A  60
VAL A  91
ILE A  88
 None
 0.91A 5mueA-1ex9A:
2.7		 5mueA-1ex9A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  88
GLY A  84
HIS A  83
TYR A 195
ALA A 102
 None
 1.12A 5n0oA-1ex9A:
undetectable		 5n0oA-1ex9A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  88
GLY A  84
HIS A  83
TYR A 195
ALA A 102
 None
 1.14A 5n0oB-1ex9A:
2.7		 5n0oB-1ex9A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  88
GLY A  84
HIS A  83
TYR A 195
ALA A 102
 None
 1.11A 5n0rA-1ex9A:
0.7		 5n0rA-1ex9A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  88
GLY A  84
HIS A  83
TYR A 195
ALA A 102
 None
 1.11A 5n0wA-1ex9A:
undetectable		 5n0wA-1ex9A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  88
GLY A  84
HIS A  83
TYR A 195
ALA A 102
 None
 1.10A 5n0wB-1ex9A:
2.4		 5n0wB-1ex9A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  88
GLY A  84
HIS A  83
TYR A 195
ALA A 102
 None
 1.13A 5n0xA-1ex9A:
undetectable		 5n0xA-1ex9A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  88
GLY A  84
HIS A  83
TYR A 195
ALA A 102
 None
 1.14A 5n0xB-1ex9A:
2.1		 5n0xB-1ex9A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 5 GLY A  84
THR A  87
HIS A  14
SER A  48
 None
 1.14A 6jmjA-1ex9A:
undetectable		 6jmjA-1ex9A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 6 GLY A  84
THR A  87
HIS A  14
SER A  48
 None
 1.11A 6jogA-1ex9A:
undetectable		 6jogA-1ex9A:
20.35