SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1exc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 1exc PROTEIN MAF
(Bacillus
subtilis) 		4 / 4 LEU A 173
SER A 169
TYR A 168
LEU A  17
 None
 1.16A 1xz1A-1excA:
undetectable		 1xz1A-1excA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 1exc PROTEIN MAF
(Bacillus
subtilis) 		4 / 4 LEU A 173
SER A 169
TYR A 168
LEU A  17
 None
 1.15A 1xz3A-1excA:
undetectable		 1xz3A-1excA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1exc PROTEIN MAF
(Bacillus
subtilis) 		4 / 6 ARG A  99
SER A 100
SER A 102
GLU A 123
 None
 1.16A 2c8aC-1excA:
undetectable		 2c8aC-1excA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1exc PROTEIN MAF
(Bacillus
subtilis) 		4 / 6 GLY A 154
ILE A 152
GLY A 156
TYR A 137
 None
 0.86A 2jklB-1excA:
undetectable		 2jklB-1excA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1exc PROTEIN MAF
(Bacillus
subtilis) 		5 / 9 PHE A 159
SER A 130
ARG A  94
ALA A  90
LEU A  93
 None
 1.21A 2wsfB-1excA:
undetectable		 2wsfB-1excA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1exc PROTEIN MAF
(Bacillus
subtilis) 		4 / 8 GLU A 139
TYR A 137
GLY A 154
ARG A 155
 None
 1.06A 4fgzA-1excA:
undetectable
4fgzB-1excA:
undetectable		 4fgzA-1excA:
20.30
4fgzB-1excA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1exc PROTEIN MAF
(Bacillus
subtilis) 		4 / 7 ALA A 125
GLY A 151
THR A 140
GLU A 142
 None
 0.98A 5bs8A-1excA:
0.0
5bs8B-1excA:
undetectable
5bs8C-1excA:
0.0		 5bs8A-1excA:
15.57
5bs8B-1excA:
22.73
5bs8C-1excA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1exc PROTEIN MAF
(Bacillus
subtilis) 		4 / 6 ALA A 125
GLY A 151
THR A 140
GLU A 142
 None
 0.97A 5btgA-1excA:
0.0
5btgB-1excA:
undetectable
5btgC-1excA:
0.0		 5btgA-1excA:
15.57
5btgB-1excA:
22.73
5btgC-1excA:
15.57