SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1exh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 1exh EXO-1,4-BETA-D-GLYCA
NASE
(Cellulomonas
fimi) 		4 / 8 GLY A  37
ASN A  69
GLY A  74
VAL A  10
 None
 0.85A 1dbbH-1exhA:
2.7
1dbbL-1exhA:
3.1		 1dbbH-1exhA:
19.82
1dbbL-1exhA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 1exh EXO-1,4-BETA-D-GLYCA
NASE
(Cellulomonas
fimi) 		3 / 3 ASN A  29
ALA A  82
ASN A  69
 None
 0.62A 1n4fA-1exhA:
0.0		 1n4fA-1exhA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1exh EXO-1,4-BETA-D-GLYCA
NASE
(Cellulomonas
fimi) 		4 / 8 PHE A  42
VAL A  25
VAL A  58
VAL A  67
 None
 1.05A 4l4bA-1exhA:
undetectable		 4l4bA-1exhA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1exh EXO-1,4-BETA-D-GLYCA
NASE
(Cellulomonas
fimi) 		4 / 8 PHE A  42
VAL A  25
VAL A  58
VAL A  67
 None
 1.07A 6cp4A-1exhA:
undetectable		 6cp4A-1exhA:
12.62