SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1exs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 1exs BETA-LACTOGLOBULIN
(Sus
scrofa) 		4 / 7 PHE A 136
THR A  21
VAL A 118
VAL A  26
 None
 1.01A 2qbnA-1exsA:
0.0		 2qbnA-1exsA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1exs BETA-LACTOGLOBULIN
(Sus
scrofa) 		5 / 12 GLY A  45
ILE A  84
LEU A  87
LEU A  94
LEU A  54
 None
 1.32A 3cs8A-1exsA:
undetectable		 3cs8A-1exsA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 1exs BETA-LACTOGLOBULIN
(Sus
scrofa) 		4 / 8 ARG A 133
VAL A  26
LEU A 150
PRO A 151
 None
 0.97A 3jq7C-1exsA:
undetectable		 3jq7C-1exsA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 1exs BETA-LACTOGLOBULIN
(Sus
scrofa) 		3 / 3 PRO A  48
THR A  49
LEU A  72
 None
 0.66A 3ttrA-1exsA:
undetectable		 3ttrA-1exsA:
17.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OMW_D_TE4D202_1
(BETA-LACTOGLOBULIN)		 1exs BETA-LACTOGLOBULIN
(Sus
scrofa) 		5 / 9 LEU A  32
GLU A  89
ASN A 109
ALA A 111
SER A 116
 None
 1.05A 4omwD-1exsA:
18.0		 4omwD-1exsA:
63.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1exs BETA-LACTOGLOBULIN
(Sus
scrofa) 		5 / 12 LEU A  46
LEU A  54
ILE A  56
LEU A  58
ILE A  84
 None
 0.62A 4y0rA-1exsA:
14.9		 4y0rA-1exsA:
64.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1exs BETA-LACTOGLOBULIN
(Sus
scrofa) 		5 / 12 LEU A  46
LEU A  54
ILE A  56
GLU A  62
MET A 107
 None
 0.70A 4y0sA-1exsA:
14.9		 4y0sA-1exsA:
63.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1exs BETA-LACTOGLOBULIN
(Sus
scrofa) 		5 / 12 LEU A  46
LEU A  54
ILE A  56
ILE A  84
LEU A 103
 None
 0.55A 4y0sA-1exsA:
14.9		 4y0sA-1exsA:
63.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1exs BETA-LACTOGLOBULIN
(Sus
scrofa) 		5 / 12 LEU A  46
LEU A  54
ILE A  56
LEU A 103
MET A 107
 None
 0.80A 4y0sA-1exsA:
14.9		 4y0sA-1exsA:
63.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1exs BETA-LACTOGLOBULIN
(Sus
scrofa) 		3 / 3 LYS A  83
ASN A  90
SER A 110
 None
 1.08A 5yw0A-1exsA:
0.0		 5yw0A-1exsA:
21.25