SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1exz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 1exz STEM CELL FACTOR
(Homo
sapiens) 		4 / 6 SER A 133
ALA A 132
HIS A  42
ASP A  97
 None
 1.33A 3aruA-1exzA:
undetectable		 3aruA-1exzA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1exz STEM CELL FACTOR
(Homo
sapiens) 		4 / 6 VAL A  15
VAL A  83
ILE A  76
ARG A 117
 None
 0.88A 3ms9A-1exzA:
undetectable		 3ms9A-1exzA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1exz STEM CELL FACTOR
(Homo
sapiens) 		4 / 7 VAL A  15
VAL A  83
ILE A  76
ARG A 117
 None
 0.91A 3ms9B-1exzA:
undetectable		 3ms9B-1exzA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1exz STEM CELL FACTOR
(Homo
sapiens) 		4 / 6 VAL A  15
VAL A  83
ILE A  76
ARG A 117
 None
 0.90A 3mssA-1exzA:
undetectable		 3mssA-1exzA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1exz STEM CELL FACTOR
(Homo
sapiens) 		4 / 6 VAL A  15
VAL A  83
ILE A  76
ARG A 117
 None
 0.92A 3mssC-1exzA:
undetectable		 3mssC-1exzA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 1exz STEM CELL FACTOR
(Homo
sapiens) 		4 / 6 VAL A  15
VAL A  83
ILE A  76
ARG A 117
 None
 0.91A 3pyyA-1exzA:
undetectable		 3pyyA-1exzA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 1exz STEM CELL FACTOR
(Homo
sapiens) 		4 / 6 THR A   9
ASN A  11
ASP A  14
ILE A  75
 None
 1.30A 3w9tB-1exzA:
0.0		 3w9tB-1exzA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 1exz STEM CELL FACTOR
(Homo
sapiens) 		3 / 3 LYS A  78
ASN A  65
ASP A  14
 None
 0.74A 4o1eA-1exzA:
undetectable		 4o1eA-1exzA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 1exz STEM CELL FACTOR
(Homo
sapiens) 		3 / 3 THR A  57
SER A  53
ASP A  85
 None
 0.83A 5kvaA-1exzA:
undetectable		 5kvaA-1exzA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 1exz STEM CELL FACTOR
(Homo
sapiens) 		3 / 3 THR A  57
SER A  53
ASP A  85
 None
 0.82A 5kvaB-1exzA:
undetectable		 5kvaB-1exzA:
20.50