SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ey1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVD_B_SAMB601_1 (CATECHOL-O-METHYLTRA NSFERASE)	1ey1	ANTITERMINATION FACTOR NUSB (Escherichia coli)	3 / 3	SER A 71 GLU A 81 ASP A 118	None	0.90A	2avdB-1ey1A: undetectable	2avdB-1ey1A: 24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TXN_A_URFA302_1 (URIDINE PHOSPHORYLASE)	1ey1	ANTITERMINATION FACTOR NUSB (Escherichia coli)	4 / 7	THR A 59 GLY A 54 ALA A 56 ILE A 27	None	0.94A	4txnA-1ey1A: undetectable	4txnA-1ey1A: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TXN_B_URFB302_1 (URIDINE PHOSPHORYLASE)	1ey1	ANTITERMINATION FACTOR NUSB (Escherichia coli)	4 / 7	THR A 59 GLY A 54 ALA A 56 ILE A 27	None	0.96A	4txnB-1ey1A: undetectable	4txnB-1ey1A: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TXN_D_URFD302_1 (URIDINE PHOSPHORYLASE)	1ey1	ANTITERMINATION FACTOR NUSB (Escherichia coli)	4 / 7	THR A 59 GLY A 54 ALA A 56 ILE A 27	None	0.95A	4txnD-1ey1A: undetectable	4txnD-1ey1A: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESH_A_1YNA602_2 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1ey1	ANTITERMINATION FACTOR NUSB (Escherichia coli)	4 / 5	TYR A 69 LEU A 92 PRO A 132 LEU A 62	None	1.40A	5eshA-1ey1A: undetectable	5eshA-1ey1A: 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OV9_B_CVIB602_0 (ACETYLCHOLINESTERASE)	1ey1	ANTITERMINATION FACTOR NUSB (Escherichia coli)	4 / 8	THR A 59 LEU A 62 TYR A 61 VAL A 133	None	1.14A	5ov9B-1ey1A: undetectable	5ov9B-1ey1A: 13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TUD_D_ERMD1201_2 (5-HYDROXYTRYPTAMINE RECEPTOR 2B,SOLUBLE CYTOCHROME B562 CHIMERA)	1ey1	ANTITERMINATION FACTOR NUSB (Escherichia coli)	4 / 6	LEU A 51 VAL A 55 THR A 59 LEU A 110	None	0.90A	5tudD-1ey1A: 0.7	5tudD-1ey1A: 14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AN0_A_HISA520_0 (HISTIDINOL DEHYDROGENASE)	1ey1	ANTITERMINATION FACTOR NUSB (Escherichia coli)	4 / 6	GLU A 50 ARG A 49 GLU A 31 ALA A 28	None	1.17A	6an0A-1ey1A: undetectable	6an0A-1ey1A: 14.54

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2AVD_B_SAMB601_1","CATECHOL-O-METHYLTRANSFERASE","1ey1","ANTITERMINATION FACTOR NUSB","Escherichia coli",3,"SER A  71;GLU A  81;ASP A 118","None","0.90A","2avdB-1ey1A:undetectable","2avdB-1ey1A:24.89"],["4TXN_A_URFA302_1","URIDINE PHOSPHORYLASE","1ey1","ANTITERMINATION FACTOR NUSB","Escherichia coli",4,"THR A  59;GLY A  54;ALA A  56;ILE A  27","None","0.94A","4txnA-1ey1A:undetectable","4txnA-1ey1A:21.38"],["4TXN_B_URFB302_1","URIDINE PHOSPHORYLASE","1ey1","ANTITERMINATION FACTOR NUSB","Escherichia coli",4,"THR A  59;GLY A  54;ALA A  56;ILE A  27","None","0.96A","4txnB-1ey1A:undetectable","4txnB-1ey1A:21.38"],["4TXN_D_URFD302_1","URIDINE PHOSPHORYLASE","1ey1","ANTITERMINATION FACTOR NUSB","Escherichia coli",4,"THR A  59;GLY A  54;ALA A  56;ILE A  27","None","0.95A","4txnD-1ey1A:undetectable","4txnD-1ey1A:21.38"],["5ESH_A_1YNA602_2","LANOSTEROL 14-ALPHA DEMETHYLASE","1ey1","ANTITERMINATION FACTOR NUSB","Escherichia coli",4,"TYR A  69;LEU A  92;PRO A 132;LEU A  62","None","1.40A","5eshA-1ey1A:undetectable","5eshA-1ey1A:14.93"],["5OV9_B_CVIB602_0","ACETYLCHOLINESTERASE","1ey1","ANTITERMINATION FACTOR NUSB","Escherichia coli",4,"THR A  59;LEU A  62;TYR A  61;VAL A 133","None","1.14A","5ov9B-1ey1A:undetectable","5ov9B-1ey1A:13.94"],["5TUD_D_ERMD1201_2","5-HYDROXYTRYPTAMINE RECEPTOR 2B,SOLUBLE CYTOCHROME B562 CHIMERA","1ey1","ANTITERMINATION FACTOR NUSB","Escherichia coli",4,"LEU A  51;VAL A  55;THR A  59;LEU A 110","None","0.90A","5tudD-1ey1A:0.7","5tudD-1ey1A:14.16"],["6AN0_A_HISA520_0","HISTIDINOL DEHYDROGENASE","1ey1","ANTITERMINATION FACTOR NUSB","Escherichia coli",4,"GLU A  50;ARG A  49;GLU A  31;ALA A  28","None","1.17A","6an0A-1ey1A:undetectable","6an0A-1ey1A:14.54"]]