SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eyp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 1eyp CHALCONE-FLAVONONE
ISOMERASE 1
(Medicago
sativa) 		5 / 11 GLU A  55
ALA A  58
ILE A  84
ASP A  83
PHE A  29
 None
 1.26A 2admA-1eypA:
undetectable		 2admA-1eypA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 1eyp CHALCONE-FLAVONONE
ISOMERASE 1
(Medicago
sativa) 		4 / 5 LEU A 201
GLY A  31
ILE A  84
ILE A 192
 None
 0.69A 2q9rA-1eypA:
0.0		 2q9rA-1eypA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 1eyp CHALCONE-FLAVONONE
ISOMERASE 1
(Medicago
sativa) 		3 / 3 PRO A 146
PHE A  47
LYS A  97
 None
 0.99A 3bjwG-1eypA:
0.0		 3bjwG-1eypA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1eyp CHALCONE-FLAVONONE
ISOMERASE 1
(Medicago
sativa) 		4 / 6 ILE A  50
PHE A 164
PHE A 144
TYR A 106
 None
 1.15A 3elzB-1eypA:
0.6		 3elzB-1eypA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 1eyp CHALCONE-FLAVONONE
ISOMERASE 1
(Medicago
sativa) 		5 / 12 ILE A  50
LEU A 160
VAL A 183
ILE A  93
THR A  48
 None
 1.10A 4m2xG-1eypA:
undetectable		 4m2xG-1eypA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 1eyp CHALCONE-FLAVONONE
ISOMERASE 1
(Medicago
sativa) 		3 / 3 GLU A 174
TYR A  28
GLU A  90
 None
 0.83A 4ryaA-1eypA:
0.0		 4ryaA-1eypA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1eyp CHALCONE-FLAVONONE
ISOMERASE 1
(Medicago
sativa) 		4 / 6 VAL A 121
LEU A 188
SER A 185
ILE A  93
 None
 0.90A 5jw1A-1eypA:
0.0		 5jw1A-1eypA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 1eyp CHALCONE-FLAVONONE
ISOMERASE 1
(Medicago
sativa) 		4 / 8 LEU A  78
ARG A  82
LEU A  75
ILE A  84
 None
 1.00A 5v0vA-1eypA:
undetectable		 5v0vA-1eypA:
19.09