SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eyv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C4D_A_DVAA6_0 (GRAMICIDIN A)	1eyv	N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG (Mycobacterium tuberculosis)	3 / 3	ALA A 32 VAL A 62 TRP A 98	None	0.99A	1c4dA-1eyvA: undetectable 1c4dB-1eyvA: undetectable	1c4dA-1eyvA: 7.09 1c4dB-1eyvA: 7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C4D_B_DVAB6_0 (GRAMICIDIN A)	1eyv	N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG (Mycobacterium tuberculosis)	3 / 3	TRP A 98 ALA A 32 VAL A 62	None	0.88A	1c4dA-1eyvA: undetectable 1c4dB-1eyvA: undetectable	1c4dA-1eyvA: 7.09 1c4dB-1eyvA: 7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C4D_D_DVAD6_0 (GRAMICIDIN A)	1eyv	N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG (Mycobacterium tuberculosis)	3 / 3	TRP A 98 ALA A 32 VAL A 62	None	0.93A	1c4dC-1eyvA: undetectable 1c4dD-1eyvA: undetectable	1c4dC-1eyvA: 7.09 1c4dD-1eyvA: 7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GC9_A_ACTA402_0 (DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL)	1eyv	N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG (Mycobacterium tuberculosis)	3 / 3	LYS A 9 TYR A 54 ARG A 14	None None PO4 A 350 (-3.0A)	1.44A	4gc9A-1eyvA: undetectable	4gc9A-1eyvA: 19.71

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C4D_A_DVAA6_0","GRAMICIDIN A","1eyv","N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG","Mycobacterium tuberculosis",3,"ALA A  32;VAL A  62;TRP A  98","None","0.99A","1c4dA-1eyvA:undetectable;1c4dB-1eyvA:undetectable","1c4dA-1eyvA:7.09;1c4dB-1eyvA:7.09"],["1C4D_B_DVAB6_0","GRAMICIDIN A","1eyv","N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG","Mycobacterium tuberculosis",3,"TRP A  98;ALA A  32;VAL A  62","None","0.88A","1c4dA-1eyvA:undetectable;1c4dB-1eyvA:undetectable","1c4dA-1eyvA:7.09;1c4dB-1eyvA:7.09"],["1C4D_D_DVAD6_0","GRAMICIDIN A","1eyv","N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG","Mycobacterium tuberculosis",3,"TRP A  98;ALA A  32;VAL A  62","None","0.93A","1c4dC-1eyvA:undetectable;1c4dD-1eyvA:undetectable","1c4dC-1eyvA:7.09;1c4dD-1eyvA:7.09"],["4GC9_A_ACTA402_0","DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL","1eyv","N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG","Mycobacterium tuberculosis",3,"LYS A   9;TYR A  54;ARG A  14","None;None;PO4 A 350 (-3.0A)","1.44A","4gc9A-1eyvA:undetectable","4gc9A-1eyvA:19.71"]]