SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eyw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		5 / 12 HIS A 254
ASP A 233
HIS A  57
ASP A 301
ASP A 253
 None
None
ZN  A 401 (-3.3A)
ZN  A 401 ( 2.6A)
None
 1.38A 1a4lB-1eywA:
14.5		 1a4lB-1eywA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 5 ASP A 301
HIS A  55
HIS A 254
HIS A 230
 ZN  A 401 ( 2.6A)
ZN  A 401 (-3.2A)
None
ZN  A 402 (-3.3A)
 0.87A 1ei6A-1eywA:
undetectable		 1ei6A-1eywA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 8 GLU A 219
ALA A 214
ALA A 176
THR A 172
 None
 0.84A 1ie4B-1eywA:
undetectable
1ie4D-1eywA:
undetectable		 1ie4B-1eywA:
20.00
1ie4D-1eywA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		3 / 3 ASP A 301
HIS A 230
HIS A  55
 ZN  A 401 ( 2.6A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
 0.68A 1oe1A-1eywA:
undetectable		 1oe1A-1eywA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		3 / 3 ASP A 301
HIS A 230
HIS A  55
 ZN  A 401 ( 2.6A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
 0.68A 1oe3A-1eywA:
undetectable		 1oe3A-1eywA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		5 / 12 ILE A 106
ASP A 100
LEU A 113
ARG A  76
LEU A  66
 TEN  A 403 ( 4.6A)
None
None
None
None
 1.32A 1rh3A-1eywA:
undetectable		 1rh3A-1eywA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 6 PHE A  72
ASN A 312
ILE A 313
ASP A 315
 None
 0.96A 1yc2A-1eywA:
undetectable		 1yc2A-1eywA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		5 / 12 HIS A  55
HIS A  57
ILE A 106
HIS A 230
ASP A 301
 ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
TEN  A 403 ( 4.6A)
ZN  A 402 (-3.3A)
ZN  A 401 ( 2.6A)
 0.88A 2pgrA-1eywA:
5.8		 2pgrA-1eywA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 8 ASP A 301
LEU A 271
HIS A 257
LEU A 303
 ZN  A 401 ( 2.6A)
None
None
None
 0.96A 2q0iA-1eywA:
undetectable		 2q0iA-1eywA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		3 / 3 CYH A  59
HIS A  57
PHE A 306
 None
ZN  A 401 (-3.3A)
TEN  A 403 (-4.4A)
 0.92A 3cr4X-1eywA:
undetectable		 3cr4X-1eywA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		6 / 11 ALA A 126
GLY A 162
GLY A 157
ILE A 124
LEU A 113
SER A 111
 None
 1.26A 3dcmX-1eywA:
2.4		 3dcmX-1eywA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		5 / 12 ASP A 235
ILE A 228
GLY A 209
GLN A 212
LEU A 252
 None
 1.18A 3eeyA-1eywA:
undetectable		 3eeyA-1eywA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		6 / 12 ASP A 235
ILE A 228
GLY A 209
GLN A 212
LEU A 252
THR A 172
 None
 1.46A 3eeyC-1eywA:
undetectable		 3eeyC-1eywA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		5 / 12 ASP A 235
ILE A 228
GLY A 209
GLN A 212
LEU A 252
 None
 1.18A 3eeyD-1eywA:
undetectable		 3eeyD-1eywA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		5 / 12 ASP A 235
GLY A 209
GLN A 212
LEU A 287
THR A 200
 None
 1.15A 3eeyE-1eywA:
undetectable		 3eeyE-1eywA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		6 / 12 ASP A 235
ILE A 228
GLY A 209
GLN A 212
LEU A 252
THR A 172
 None
 1.45A 3eeyE-1eywA:
undetectable		 3eeyE-1eywA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		5 / 12 ASP A 235
GLY A 209
GLN A 212
LEU A 287
THR A 200
 None
 1.15A 3eeyF-1eywA:
undetectable		 3eeyF-1eywA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		6 / 12 ASP A 235
ILE A 228
GLY A 209
GLN A 212
LEU A 252
THR A 172
 None
 1.45A 3eeyF-1eywA:
undetectable		 3eeyF-1eywA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		5 / 12 ASP A 235
ILE A 228
GLY A 209
GLN A 212
LEU A 252
 None
 1.15A 3eeyJ-1eywA:
undetectable		 3eeyJ-1eywA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 5 ASP A 253
ILE A 228
VAL A 198
THR A 103
 None
None
None
KCX  A 169 ( 4.3A)
 0.83A 3eigA-1eywA:
undetectable		 3eigA-1eywA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		3 / 3 ILE A 228
PHE A 216
HIS A  55
 None
None
ZN  A 401 (-3.2A)
 0.72A 3h0aA-1eywA:
undetectable		 3h0aA-1eywA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		3 / 3 ILE A 228
PHE A 216
HIS A 201
 None
None
ZN  A 402 (-3.1A)
 0.76A 3h0aA-1eywA:
undetectable		 3h0aA-1eywA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		5 / 9 LEU A 297
THR A  54
HIS A  55
HIS A 230
ILE A 228
 None
None
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
None
 1.31A 3hy7B-1eywA:
undetectable		 3hy7B-1eywA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 8 THR A 128
LEU A 130
ALA A 186
ALA A 187
 None
 0.92A 3ns1L-1eywA:
0.0		 3ns1L-1eywA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		5 / 12 GLY A 166
LEU A 192
GLY A 195
ALA A 187
ALA A 188
 None
 0.88A 3sufA-1eywA:
undetectable		 3sufA-1eywA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		5 / 9 LEU A 237
ALA A 286
LEU A 252
TYR A 292
THR A 241
 None
 1.44A 4ltwA-1eywA:
undetectable		 4ltwA-1eywA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		5 / 6 HIS A  55
HIS A  57
HIS A 201
HIS A 230
ASP A 301
 ZN  A 401 (-3.2A)
ZN  A 401 (-3.3A)
ZN  A 402 (-3.1A)
ZN  A 402 (-3.3A)
ZN  A 401 ( 2.6A)
 0.70A 4ubpC-1eywA:
14.6		 4ubpC-1eywA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 5 PHE A 216
PRO A 223
VAL A 226
ALA A 213
 None
 1.07A 4w5oA-1eywA:
undetectable		 4w5oA-1eywA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 5 PHE A 216
PRO A 223
VAL A 226
ALA A 213
 None
 1.07A 4z4cA-1eywA:
undetectable		 4z4cA-1eywA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 5 PHE A 216
PRO A 223
VAL A 226
ALA A 213
 None
 1.07A 4z4dA-1eywA:
undetectable		 4z4dA-1eywA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 5 PHE A 216
PRO A 223
VAL A 226
ALA A 213
 None
 1.05A 4z4eA-1eywA:
undetectable		 4z4eA-1eywA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 6 HIS A  55
ASP A 301
HIS A  57
TRP A 131
 ZN  A 401 (-3.2A)
ZN  A 401 ( 2.6A)
ZN  A 401 (-3.3A)
TEN  A 403 (-4.4A)
 1.24A 5m45A-1eywA:
0.0		 5m45A-1eywA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 6 HIS A  55
ASP A 301
HIS A  57
TRP A 131
 ZN  A 401 (-3.2A)
ZN  A 401 ( 2.6A)
ZN  A 401 (-3.3A)
TEN  A 403 (-4.4A)
 1.25A 5m45D-1eywA:
0.0		 5m45D-1eywA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 6 HIS A  55
ASP A 301
HIS A  57
TRP A 131
 ZN  A 401 (-3.2A)
ZN  A 401 ( 2.6A)
ZN  A 401 (-3.3A)
TEN  A 403 (-4.4A)
 1.25A 5m45G-1eywA:
0.0		 5m45G-1eywA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 6 HIS A  55
ASP A 301
HIS A  57
TRP A 131
 ZN  A 401 (-3.2A)
ZN  A 401 ( 2.6A)
ZN  A 401 (-3.3A)
TEN  A 403 (-4.4A)
 1.25A 5m45J-1eywA:
0.0		 5m45J-1eywA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 6 ASP A 301
ASP A 253
HIS A 254
HIS A  55
 ZN  A 401 ( 2.6A)
None
None
ZN  A 401 (-3.2A)
 0.76A 5ncdA-1eywA:
3.3
5ncdD-1eywA:
3.9		 5ncdA-1eywA:
21.43
5ncdD-1eywA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 6 ASP A 301
ASP A 253
HIS A 254
HIS A  55
 ZN  A 401 ( 2.6A)
None
None
ZN  A 401 (-3.2A)
 0.73A 5ncdB-1eywA:
4.6
5ncdC-1eywA:
4.5		 5ncdB-1eywA:
21.43
5ncdC-1eywA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 8 ASP A 301
ASP A 253
HIS A 254
HIS A  55
 ZN  A 401 ( 2.6A)
None
None
ZN  A 401 (-3.2A)
 0.72A 5nekB-1eywA:
undetectable		 5nekB-1eywA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 8 ASP A 301
ASP A 253
HIS A 254
HIS A  55
 ZN  A 401 ( 2.6A)
None
None
ZN  A 401 (-3.2A)
 0.77A 5nekD-1eywA:
undetectable		 5nekD-1eywA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 6 ASP A 301
ASP A 253
HIS A 254
HIS A  55
 ZN  A 401 ( 2.6A)
None
None
ZN  A 401 (-3.2A)
 0.73A 5nelA-1eywA:
4.5
5nelD-1eywA:
3.2		 5nelA-1eywA:
21.43
5nelD-1eywA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 6 PHE A 216
PRO A 223
VAL A 226
ALA A 213
 None
 1.05A 5t7bA-1eywA:
undetectable		 5t7bA-1eywA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 5 ARG A 246
ALA A 242
TYR A 239
ILE A 250
 None
 1.18A 6f6sA-1eywA:
0.0
6f6sB-1eywA:
undetectable		 6f6sA-1eywA:
13.68
6f6sB-1eywA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 5 ARG A 246
ALA A 242
TYR A 239
ILE A 228
 None
 1.33A 6g9bA-1eywA:
0.0
6g9bB-1eywA:
undetectable		 6g9bA-1eywA:
13.68
6g9bB-1eywA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 1eyw PHOSPHOTRIESTERASE
(Brevundimonas
diminuta) 		4 / 5 ARG A 246
ALA A 242
TYR A 239
ILE A 250
 None
 1.22A 6g9bA-1eywA:
0.0
6g9bB-1eywA:
undetectable		 6g9bA-1eywA:
13.68
6g9bB-1eywA:
14.11