SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1eyy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_B_FOLB187_0
(DIHYDROFOLATE
REDUCTASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 12 GLN A 418
THR A 260
ILE A 409
LEU A 422
THR A 300
 None
 1.13A 1dhfB-1eyyA:
undetectable		 1dhfB-1eyyA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 6 ASN A 147
HIS A 177
ALA A 145
GLY A 229
 None
None
None
NAP  A 650 (-3.7A)
 1.12A 1l7xA-1eyyA:
2.8		 1l7xA-1eyyA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 6 ASN A 147
HIS A 177
ALA A 145
GLY A 229
 None
None
None
NAP  A 650 (-3.7A)
 1.14A 1l7xB-1eyyA:
2.2		 1l7xB-1eyyA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 5 GLY A 466
GLN A  97
VAL A 442
SER A 464
 None
 1.10A 1p6kB-1eyyA:
0.0		 1p6kB-1eyyA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 8 ALA A  95
GLU A  66
ASP A  70
ILE A 183
 None
 0.88A 1p7lD-1eyyA:
undetectable		 1p7lD-1eyyA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 8 ALA A  95
GLU A  66
ASP A  70
ILE A 183
 None
 0.87A 1p7lC-1eyyA:
undetectable		 1p7lC-1eyyA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q0Y_H_MOIH401_1
(FAB 9B1, HEAVY CHAIN
FAB 9B1, LIGHT CHAIN)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 7 TRP A 368
GLU A 375
ILE A 257
LEU A 397
 None
 1.29A 1q0yH-1eyyA:
undetectable
1q0yL-1eyyA:
0.0		 1q0yH-1eyyA:
17.84
1q0yL-1eyyA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 8 ALA A  95
GLU A  66
ASP A  70
ILE A 183
 None
 0.90A 1rg9B-1eyyA:
undetectable		 1rg9B-1eyyA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 8 ALA A  95
GLU A  66
ASP A  70
ILE A 183
 None
 0.88A 1rg9A-1eyyA:
undetectable		 1rg9A-1eyyA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 8 ALA A  95
GLU A  66
ASP A  70
ILE A 183
 None
 0.89A 1rg9D-1eyyA:
1.0		 1rg9D-1eyyA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 8 ALA A  95
GLU A  66
ASP A  70
ILE A 183
 None
 0.88A 1rg9C-1eyyA:
undetectable		 1rg9C-1eyyA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 5 GLY A 466
GLN A  97
VAL A 442
SER A 464
 None
 1.10A 1rs6B-1eyyA:
0.0		 1rs6B-1eyyA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 5 ILE A 183
LEU A 150
ALA A  76
GLU A  79
 None
 0.88A 1xvaA-1eyyA:
4.0
1xvaB-1eyyA:
4.0		 1xvaA-1eyyA:
20.16
1xvaB-1eyyA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 5 GLY A 466
GLN A  97
VAL A 442
SER A 464
 None
 1.30A 1zzqB-1eyyA:
0.0		 1zzqB-1eyyA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 5 GLY A 466
GLN A  97
VAL A 442
SER A 464
 None
 1.08A 1zzuB-1eyyA:
0.0		 1zzuB-1eyyA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 5 SER A 358
VAL A 356
SER A 318
SER A 320
 None
 1.37A 2j9cA-1eyyA:
0.0
2j9cB-1eyyA:
0.0
2j9cC-1eyyA:
0.0		 2j9cA-1eyyA:
11.85
2j9cB-1eyyA:
11.85
2j9cC-1eyyA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 7 SER A 320
SER A 358
VAL A 356
SER A 318
 None
 1.45A 2j9cA-1eyyA:
0.0
2j9cB-1eyyA:
0.0
2j9cC-1eyyA:
0.0		 2j9cA-1eyyA:
11.85
2j9cB-1eyyA:
11.85
2j9cC-1eyyA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 6 THR A  16
THR A  12
THR A 180
ASP A  71
 None
 1.05A 2okcB-1eyyA:
3.8		 2okcB-1eyyA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		3 / 3 LEU A  82
PRO A  83
ARG A  93
 None
 0.66A 2qd5A-1eyyA:
2.2		 2qd5A-1eyyA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 10 PHE A  46
SER A 490
ILE A 499
LEU A  98
GLY A 166
 None
 1.23A 2v0mA-1eyyA:
undetectable		 2v0mA-1eyyA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_B_TOPB1189_1
(DIHYDROFOLATE
REDUCTASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 10 ALA A 145
THR A 180
ILE A  72
LEU A  65
THR A 228
 None
 1.23A 2w3aB-1eyyA:
undetectable		 2w3aB-1eyyA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 6 ASP A 415
TYR A 416
PHE A 261
LEU A 426
 None
 1.03A 2w98A-1eyyA:
2.8
2w98B-1eyyA:
4.2		 2w98A-1eyyA:
21.78
2w98B-1eyyA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		3 / 3 LEU A 322
TYR A 331
GLN A 332
 None
 0.73A 2wekA-1eyyA:
4.1		 2wekA-1eyyA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 6 ALA A 215
LEU A 216
ALA A  36
THR A  37
 None
 0.92A 3b6hB-1eyyA:
0.0		 3b6hB-1eyyA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 6 ASN A 147
HIS A 177
ALA A 145
GLY A 229
 None
None
None
NAP  A 650 (-3.7A)
 1.14A 3dd1A-1eyyA:
undetectable		 3dd1A-1eyyA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 6 ASN A 147
HIS A 177
ALA A 145
GLY A 229
 None
None
None
NAP  A 650 (-3.7A)
 1.15A 3ddwA-1eyyA:
3.7		 3ddwA-1eyyA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 6 ASN A 147
HIS A 177
ALA A 145
GLY A 229
 None
None
None
NAP  A 650 (-3.7A)
 1.14A 3ddwB-1eyyA:
undetectable		 3ddwB-1eyyA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 6 MET A 281
ILE A 314
ILE A 385
LEU A 384
 None
 0.79A 3hegA-1eyyA:
undetectable		 3hegA-1eyyA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 11 VAL A 171
LEU A 204
ILE A 188
ALA A 155
SER A 153
 None
 1.16A 3n8yA-1eyyA:
0.0		 3n8yA-1eyyA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 5 VAL A 171
LEU A 204
ILE A 188
ALA A 155
 None
 0.93A 3n8yB-1eyyA:
0.0		 3n8yB-1eyyA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 12 LEU A 100
GLY A 157
ALA A 160
ALA A 164
LEU A  58
 None
 1.12A 3p5nA-1eyyA:
0.0		 3p5nA-1eyyA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 12 LEU A 100
GLY A 157
ALA A 160
ALA A 164
LEU A  58
 None
 1.12A 3p5nB-1eyyA:
undetectable		 3p5nB-1eyyA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 12 GLY A 156
ALA A 160
PHE A 101
ALA A 469
SER A 462
 None
 1.08A 3sudA-1eyyA:
undetectable		 3sudA-1eyyA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 8 ILE A 201
THR A 159
LEU A  58
VAL A 105
 None
 0.81A 3ua5A-1eyyA:
1.2		 3ua5A-1eyyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC0_A_MIYA1204_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS B FROM
TRANSPOSON TN1 0)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 12 PHE A 288
ASN A 147
THR A 290
LEU A 405
LEU A 254
 None
 1.40A 4ac0A-1eyyA:
0.0		 4ac0A-1eyyA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 6 ALA A 236
GLY A 213
LEU A 240
VAL A 217
 NAP  A 650 ( 4.1A)
NAP  A 650 ( 3.9A)
None
None
 0.85A 4dubB-1eyyA:
undetectable		 4dubB-1eyyA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 8 ILE A 314
ILE A 385
PHE A 361
GLY A 339
 None
 0.84A 4hb6A-1eyyA:
undetectable		 4hb6A-1eyyA:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 8 ILE A 314
ILE A 385
PHE A 361
GLY A 339
 None
 0.68A 4hb8A-1eyyA:
undetectable		 4hb8A-1eyyA:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 8 ILE A 314
ILE A 385
PHE A 361
GLY A 339
 None
 0.86A 4hdlA-1eyyA:
0.0		 4hdlA-1eyyA:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 11 GLN A  34
ALA A  35
ALA A  38
ALA A  39
LEU A 192
 None
 1.01A 4j6cA-1eyyA:
0.0		 4j6cA-1eyyA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 10 GLN A  34
ALA A  35
ALA A  38
ALA A  39
LEU A 192
 None
 1.03A 4j6cB-1eyyA:
0.0		 4j6cB-1eyyA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 8 ALA A  95
GLU A  66
ASP A  70
ILE A 183
 None
 0.84A 4kttB-1eyyA:
0.0		 4kttB-1eyyA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		3 / 3 GLY A 326
PRO A 325
ALA A  14
 None
 0.39A 4qn9B-1eyyA:
0.2		 4qn9B-1eyyA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 7 TYR A 446
ALA A 469
LEU A 100
PHE A 101
 None
 1.05A 4uymA-1eyyA:
0.0		 4uymA-1eyyA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 8 ALA A 162
VAL A 169
GLY A 166
ALA A 136
GLY A 138
 None
 1.39A 4zjzB-1eyyA:
3.0		 4zjzB-1eyyA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		3 / 3 ALA A 236
ASN A 239
LEU A 240
 NAP  A 650 ( 4.1A)
None
None
 0.49A 5i1oA-1eyyA:
0.0		 5i1oA-1eyyA:
5.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 7 GLY A 156
THR A 159
VAL A 171
VAL A 142
 None
 0.80A 5ik1A-1eyyA:
undetectable		 5ik1A-1eyyA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		3 / 3 ILE A 385
VAL A 295
PRO A 292
 None
 0.62A 5uunA-1eyyA:
0.0		 5uunA-1eyyA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 12 LEU A  65
ILE A  72
ALA A  76
THR A  80
GLY A 144
 None
 0.88A 5veuA-1eyyA:
0.0		 5veuA-1eyyA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 12 LEU A  65
ILE A  72
ALA A  76
ALA A 145
GLY A 173
 None
 0.97A 5veuB-1eyyA:
0.0		 5veuB-1eyyA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 12 LEU A  65
ILE A  72
ALA A  76
THR A  80
GLY A 144
 None
 0.79A 5veuB-1eyyA:
0.0		 5veuB-1eyyA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 12 LEU A  65
ILE A  72
ALA A  76
THR A  80
GLY A 144
 None
 0.83A 5veuH-1eyyA:
0.0		 5veuH-1eyyA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		5 / 12 LEU A  65
ILE A  72
ALA A  76
THR A  80
GLY A 173
 None
 1.07A 5veuH-1eyyA:
0.0		 5veuH-1eyyA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1eyy ALDEHYDE
DEHYDROGENASE
(Vibrio
harveyi) 		4 / 5 GLY A 466
GLN A  97
VAL A 442
SER A 464
 None
 1.10A 5vunA-1eyyA:
0.0		 5vunA-1eyyA:
21.47