SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ezi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 11 GLY A 112
THR A  35
HIS A  34
ILE A 115
ALA A 177
 None
 1.12A 1gtnM-1eziA:
undetectable
1gtnN-1eziA:
undetectable		 1gtnM-1eziA:
17.03
1gtnN-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 12 LEU A 103
GLY A  33
GLY A  65
ALA A   7
ILE A   9
 None
 0.84A 1rl8B-1eziA:
undetectable		 1rl8B-1eziA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 GLY A 112
THR A  35
HIS A  34
ILE A 115
ALA A 177
 None
 1.14A 1utdT-1eziA:
undetectable
1utdU-1eziA:
undetectable		 1utdT-1eziA:
17.03
1utdU-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		4 / 8 GLU A  91
ALA A  89
THR A 183
ILE A  93
 None
 0.85A 2dtjA-1eziA:
undetectable
2dtjB-1eziA:
undetectable		 2dtjA-1eziA:
23.05
2dtjB-1eziA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 12 LEU A 103
GLY A  33
GLY A  65
ALA A   7
ILE A   9
 None
 0.97A 2nmyB-1eziA:
undetectable		 2nmyB-1eziA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		3 / 3 LEU A 168
PRO A 169
LEU A 141
 None
 0.49A 2qd5B-1eziA:
2.8		 2qd5B-1eziA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		4 / 7 ASN A 181
SER A 129
THR A 197
VAL A 131
 None
 1.18A 2uz2A-1eziA:
undetectable		 2uz2A-1eziA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3007_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 9 ASN A  96
THR A 183
ALA A 184
LEU A 186
ALA A 188
 None
 1.40A 3kp6B-1eziA:
0.0		 3kp6B-1eziA:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		3 / 3 GLU A  60
ALA A  61
PHE A  64
 None
 0.57A 4v1fA-1eziA:
undetectable		 4v1fA-1eziA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		3 / 3 GLU A  60
ALA A  61
PHE A  64
 None
 0.58A 4v1fC-1eziA:
undetectable		 4v1fC-1eziA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 12 VAL A  66
ILE A  49
ILE A  36
GLY A  33
LEU A  23
 None
 1.03A 4y8wC-1eziA:
0.0		 4y8wC-1eziA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		4 / 5 LEU A 102
PHE A  45
ILE A 178
ILE A 115
 None
 0.96A 5dzk4-1eziA:
undetectable
5dzkg-1eziA:
undetectable
5dzkm-1eziA:
0.0
5dzkn-1eziA:
undetectable		 5dzk4-1eziA:
1.94
5dzkg-1eziA:
22.27
5dzkm-1eziA:
24.15
5dzkn-1eziA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
HIS A 114
THR A  35
HIS A  34
 None
 1.11A 5eeuF-1eziA:
undetectable
5eeuG-1eziA:
undetectable		 5eeuF-1eziA:
17.03
5eeuG-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
THR A  35
HIS A  34
ILE A 115
 None
 1.11A 5eeuF-1eziA:
undetectable
5eeuG-1eziA:
undetectable		 5eeuF-1eziA:
17.03
5eeuG-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 12 ALA A 177
GLY A 112
THR A  35
HIS A  34
ILE A 115
 None
 1.14A 5eeuI-1eziA:
undetectable
5eeuJ-1eziA:
undetectable		 5eeuI-1eziA:
17.03
5eeuJ-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 GLY A 112
THR A  35
HIS A  34
ILE A 115
ALA A 177
 None
 1.16A 5eeuO-1eziA:
undetectable
5eeuP-1eziA:
undetectable		 5eeuO-1eziA:
17.03
5eeuP-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 GLY A 112
THR A  35
HIS A  34
ILE A 115
ALA A 177
 None
 1.17A 5eeuQ-1eziA:
undetectable
5eeuR-1eziA:
undetectable		 5eeuQ-1eziA:
17.03
5eeuR-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
HIS A 114
THR A  35
HIS A  34
 None
 1.11A 5eevF-1eziA:
undetectable
5eevG-1eziA:
undetectable		 5eevF-1eziA:
17.03
5eevG-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
THR A  35
HIS A  34
ILE A 115
 None
 1.11A 5eevF-1eziA:
undetectable
5eevG-1eziA:
undetectable		 5eevF-1eziA:
17.03
5eevG-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 12 ALA A 177
GLY A 112
THR A  35
HIS A  34
ILE A 115
 None
 1.14A 5eevI-1eziA:
undetectable
5eevJ-1eziA:
undetectable		 5eevI-1eziA:
17.03
5eevJ-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 GLY A 112
THR A  35
HIS A  34
ILE A 115
ALA A 177
 None
 1.17A 5eevQ-1eziA:
undetectable
5eevR-1eziA:
undetectable		 5eevQ-1eziA:
17.03
5eevR-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
HIS A 114
THR A  35
HIS A  34
 None
 1.11A 5eewF-1eziA:
undetectable
5eewG-1eziA:
undetectable		 5eewF-1eziA:
17.03
5eewG-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
THR A  35
HIS A  34
ILE A 115
 None
 1.11A 5eewF-1eziA:
undetectable
5eewG-1eziA:
undetectable		 5eewF-1eziA:
17.03
5eewG-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 12 ALA A 177
GLY A 112
THR A  35
HIS A  34
ILE A 115
 None
 1.14A 5eewI-1eziA:
undetectable
5eewJ-1eziA:
undetectable		 5eewI-1eziA:
17.03
5eewJ-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 GLY A 112
THR A  35
HIS A  34
ILE A 115
ALA A 177
 None
 1.17A 5eewQ-1eziA:
undetectable
5eewR-1eziA:
undetectable		 5eewQ-1eziA:
17.03
5eewR-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
HIS A 114
THR A  35
HIS A  34
 None
 1.11A 5eexF-1eziA:
undetectable
5eexG-1eziA:
undetectable		 5eexF-1eziA:
17.03
5eexG-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
THR A  35
HIS A  34
ILE A 115
 None
 1.11A 5eexF-1eziA:
undetectable
5eexG-1eziA:
undetectable		 5eexF-1eziA:
17.03
5eexG-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
HIS A 114
THR A  35
HIS A  34
 None
 1.11A 5eeyF-1eziA:
undetectable
5eeyG-1eziA:
undetectable		 5eeyF-1eziA:
17.03
5eeyG-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
THR A  35
HIS A  34
ILE A 115
 None
 1.11A 5eeyF-1eziA:
undetectable
5eeyG-1eziA:
undetectable		 5eeyF-1eziA:
17.03
5eeyG-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
HIS A 114
THR A  35
HIS A  34
 None
 1.12A 5eezF-1eziA:
undetectable
5eezG-1eziA:
undetectable		 5eezF-1eziA:
17.03
5eezG-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
THR A  35
HIS A  34
ILE A 115
 None
 1.11A 5eezF-1eziA:
undetectable
5eezG-1eziA:
undetectable		 5eezF-1eziA:
17.03
5eezG-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
HIS A 114
THR A  35
HIS A  34
 None
 1.11A 5ef0F-1eziA:
undetectable
5ef0G-1eziA:
undetectable		 5ef0F-1eziA:
17.03
5ef0G-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
THR A  35
HIS A  34
ILE A 115
 None
 1.11A 5ef0F-1eziA:
undetectable
5ef0G-1eziA:
undetectable		 5ef0F-1eziA:
17.03
5ef0G-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
HIS A 114
THR A  35
HIS A  34
 None
 1.12A 5ef1F-1eziA:
undetectable
5ef1G-1eziA:
undetectable		 5ef1F-1eziA:
17.03
5ef1G-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
THR A  35
HIS A  34
ILE A 115
 None
 1.12A 5ef1F-1eziA:
undetectable
5ef1G-1eziA:
undetectable		 5ef1F-1eziA:
17.03
5ef1G-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
HIS A 114
THR A  35
HIS A  34
 None
 1.12A 5ef2F-1eziA:
undetectable
5ef2G-1eziA:
undetectable		 5ef2F-1eziA:
17.03
5ef2G-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
THR A  35
HIS A  34
ILE A 115
 None
 1.12A 5ef2F-1eziA:
undetectable
5ef2G-1eziA:
undetectable		 5ef2F-1eziA:
17.03
5ef2G-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
HIS A 114
THR A  35
HIS A  34
 None
 1.12A 5ef3F-1eziA:
undetectable
5ef3G-1eziA:
undetectable		 5ef3F-1eziA:
17.03
5ef3G-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 10 ALA A 177
GLY A 112
THR A  35
HIS A  34
ILE A 115
 None
 1.11A 5ef3F-1eziA:
undetectable
5ef3G-1eziA:
undetectable		 5ef3F-1eziA:
17.03
5ef3G-1eziA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EUM_B_ACTB603_0
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		4 / 4 ALA A 177
ASN A 175
ARG A 110
ILE A 178
 None
 1.36A 5eumB-1eziA:
0.4		 5eumB-1eziA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		5 / 9 ILE A  49
ALA A   7
ILE A   6
ALA A  89
LEU A  90
 None
 1.11A 5mvmA-1eziA:
0.0
5mvmE-1eziA:
0.0		 5mvmA-1eziA:
14.60
5mvmE-1eziA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1ezi CMP-N-ACETYLNEURAMIN
IC ACID SYNTHETASE
(Neisseria
meningitidis) 		3 / 3 LEU A  10
ALA A  11
LEU A 102
 None
 0.48A 5uunB-1eziA:
0.0		 5uunB-1eziA:
21.10