SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f0x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 ARG A 464
ASP A 246
ASP A 248
TYR A 228
 None
 1.20A 1ceaB-1f0xA:
0.0		 1ceaB-1f0xA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 ASP A 194
ASP A 214
LYS A 205
 None
 1.05A 1lqtB-1f0xA:
undetectable		 1lqtB-1f0xA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 ASP A 194
ASP A 214
LYS A 205
 None
 1.04A 1lquB-1f0xA:
undetectable		 1lquB-1f0xA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 8 SER A  85
ILE A 558
GLY A 557
GLY A  44
 FAD  A 600 (-2.5A)
None
None
None
 0.72A 1me7A-1f0xA:
undetectable		 1me7A-1f0xA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 5 GLU A 512
LEU A 518
LEU A 515
LEU A 517
 None
 0.93A 1np1A-1f0xA:
0.0		 1np1A-1f0xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 LEU A  16
ALA A  46
ALA A  48
VAL A  20
PHE A  12
 None
 1.27A 1rlbE-1f0xA:
undetectable		 1rlbE-1f0xA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A5H_A_SAMA417_0
(L-LYSINE
2,3-AMINOMUTASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 HIS A 489
HIS A 496
GLN A 497
VAL A 494
CYH A 492
 FAD  A 600 ( 4.6A)
None
None
None
None
 1.29A 2a5hA-1f0xA:
0.0		 2a5hA-1f0xA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A5H_B_SAMB417_0
(L-LYSINE
2,3-AMINOMUTASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 HIS A 489
HIS A 496
GLN A 497
VAL A 494
CYH A 492
 FAD  A 600 ( 4.6A)
None
None
None
None
 1.30A 2a5hB-1f0xA:
0.0		 2a5hB-1f0xA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A5H_C_SAMC417_0
(L-LYSINE
2,3-AMINOMUTASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 HIS A 489
HIS A 496
GLN A 497
VAL A 494
CYH A 492
 FAD  A 600 ( 4.6A)
None
None
None
None
 1.30A 2a5hC-1f0xA:
0.0		 2a5hC-1f0xA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A5H_D_SAMD417_0
(L-LYSINE
2,3-AMINOMUTASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 HIS A 489
HIS A 496
GLN A 497
VAL A 494
CYH A 492
 FAD  A 600 ( 4.6A)
None
None
None
None
 1.30A 2a5hD-1f0xA:
0.0		 2a5hD-1f0xA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 LEU A 267
GLY A 161
ILE A 142
PRO A 138
 None
FAD  A 600 ( 4.0A)
FAD  A 600 (-3.7A)
None
 0.78A 2aojB-1f0xA:
undetectable		 2aojB-1f0xA:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 9 THR A 269
ALA A 118
TYR A 119
LEU A 107
LEU A 175
 None
 1.25A 2azqA-1f0xA:
0.2		 2azqA-1f0xA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 TYR A 228
GLU A 308
HIS A 489
GLY A 488
 None
None
FAD  A 600 ( 4.6A)
None
 1.21A 2ha4B-1f0xA:
undetectable		 2ha4B-1f0xA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 5 LEU A 510
LEU A 456
LEU A 485
MET A 514
 None
 1.07A 2oaxF-1f0xA:
0.0		 2oaxF-1f0xA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 6 LEU A 206
LEU A 203
ILE A 211
ARG A 210
 None
 1.09A 2rlfB-1f0xA:
0.0
2rlfC-1f0xA:
0.0		 2rlfB-1f0xA:
7.24
2rlfC-1f0xA:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 7 ALA A  76
GLY A 153
VAL A 151
ASP A 105
LEU A 102
 FAD  A 600 (-3.4A)
FAD  A 600 ( 3.8A)
None
None
None
 1.39A 2uyqA-1f0xA:
undetectable		 2uyqA-1f0xA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 PRO A 199
LEU A 187
ALA A 177
PHE A 263
 None
 0.99A 2vcvA-1f0xA:
0.0		 2vcvA-1f0xA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 9 PRO A 199
LEU A 203
LEU A 187
ALA A 177
PHE A 263
 None
 0.99A 2vcvD-1f0xA:
0.0		 2vcvD-1f0xA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 9 PRO A 199
LEU A 203
LEU A 187
ALA A 177
PHE A 263
 None
 0.96A 2vcvE-1f0xA:
0.0		 2vcvE-1f0xA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 8 LEU A  56
PRO A 199
LEU A 187
ALA A 177
PHE A 263
 None
 1.27A 2vcvF-1f0xA:
undetectable		 2vcvF-1f0xA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 9 PRO A 199
LEU A 203
LEU A 187
ALA A 177
PHE A 263
 None
 1.00A 2vcvH-1f0xA:
0.0		 2vcvH-1f0xA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 9 PRO A 199
LEU A 203
LEU A 187
ALA A 177
PHE A 263
 None
 0.90A 2vcvI-1f0xA:
0.1		 2vcvI-1f0xA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 PRO A 120
THR A 101
LEU A  58
ILE A  72
LEU A 185
 FAD  A 600 ( 4.5A)
FAD  A 600 ( 4.2A)
None
None
None
 1.29A 3a51B-1f0xA:
0.0		 3a51B-1f0xA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 6 TYR A 119
ALA A 118
LEU A 117
ASN A 189
 None
 0.90A 3b6hB-1f0xA:
0.0		 3b6hB-1f0xA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_0
(COMT PROTEIN)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 VAL A 494
GLU A 308
GLY A 307
TYR A 309
ILE A 281
 None
 1.31A 3bwyA-1f0xA:
undetectable		 3bwyA-1f0xA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 MET A  74
CYH A  65
PRO A  52
 FAD  A 600 (-4.7A)
None
None
 1.15A 3h52C-1f0xA:
0.0		 3h52C-1f0xA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 4 LEU A 104
PRO A 120
LEU A  58
ARG A  60
 None
FAD  A 600 ( 4.5A)
None
None
 1.37A 3hcoB-1f0xA:
undetectable		 3hcoB-1f0xA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA A 169
SER A 159
GLU A 528
ILE A 142
LEU A 163
 None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.1A)
FAD  A 600 (-3.7A)
None
 1.10A 3k2hA-1f0xA:
0.0		 3k2hA-1f0xA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA A 169
SER A 159
GLU A 528
ILE A 142
LEU A 163
 None
FAD  A 600 (-4.5A)
FAD  A 600 (-3.1A)
FAD  A 600 (-3.7A)
None
 1.12A 3k2hB-1f0xA:
0.0		 3k2hB-1f0xA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 LEU A 481
LYS A 502
VAL A 505
LEU A 456
 None
 1.14A 4b3qA-1f0xA:
4.7		 4b3qA-1f0xA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 VAL A  61
CYH A  65
ARG A  18
VAL A  50
LEU A  25
 None
 1.44A 4po0A-1f0xA:
2.0		 4po0A-1f0xA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 VAL A 494
GLU A 308
GLY A 307
TYR A 309
ILE A 281
 None
 1.30A 4xucA-1f0xA:
undetectable		 4xucA-1f0xA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 VAL A 494
GLU A 308
GLY A 307
TYR A 309
ILE A 281
 None
 1.34A 4xudA-1f0xA:
undetectable		 4xudA-1f0xA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 GLU A 172
HIS A 222
ASP A 248
 None
 0.82A 5c0oG-1f0xA:
undetectable		 5c0oG-1f0xA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 4 LEU A 393
ILE A 281
GLY A 307
ILE A 292
 None
 0.87A 5dzk3-1f0xA:
undetectable
5dzkm-1f0xA:
undetectable		 5dzk3-1f0xA:
7.69
5dzkm-1f0xA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 5 ILE A 281
GLY A 307
ILE A 292
LEU A 393
 None
 0.85A 5dzkB-1f0xA:
undetectable
5dzkI-1f0xA:
0.0
5dzkW-1f0xA:
undetectable		 5dzkB-1f0xA:
15.26
5dzkI-1f0xA:
16.64
5dzkW-1f0xA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 5 ILE A 281
GLY A 307
ILE A 292
LEU A 393
 None
 0.88A 5dzki-1f0xA:
0.0
5dzkj-1f0xA:
undetectable
5dzkx-1f0xA:
undetectable		 5dzki-1f0xA:
16.64
5dzkj-1f0xA:
16.64
5dzkx-1f0xA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 THR A 186
LEU A 187
LEU A  58
MET A 554
ILE A  72
 None
 1.02A 5gs4A-1f0xA:
undetectable		 5gs4A-1f0xA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 5 LEU A  25
PHE A  51
LEU A  16
PHE A  12
 None
 1.15A 5iy5P-1f0xA:
undetectable
5iy5W-1f0xA:
0.0		 5iy5P-1f0xA:
18.18
5iy5W-1f0xA:
6.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 VAL A 494
GLU A 308
GLY A 307
TYR A 309
ILE A 281
 None
 1.31A 5lsaA-1f0xA:
undetectable		 5lsaA-1f0xA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 8 VAL A 216
GLY A 113
GLN A 115
THR A 269
 None
 0.93A 5sxqA-1f0xA:
0.0		 5sxqA-1f0xA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 8 VAL A 216
GLY A 113
GLN A 115
THR A 269
 None
 0.94A 5sxtA-1f0xA:
3.1		 5sxtA-1f0xA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 8 VAL A 216
GLY A 113
GLN A 115
THR A 269
 None
 0.93A 5sxtB-1f0xA:
3.4		 5sxtB-1f0xA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 LEU A  56
LEU A  55
ILE A  99
LEU A 104
LEU A  19
 None
 0.94A 5toaA-1f0xA:
undetectable		 5toaA-1f0xA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 LEU A  62
LEU A  56
ILE A  99
LEU A 104
LEU A  19
 None
 1.05A 5toaA-1f0xA:
undetectable		 5toaA-1f0xA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 5 LEU A  25
PHE A  51
LEU A  16
PHE A  12
 None
 1.18A 5xdxC-1f0xA:
undetectable
5xdxJ-1f0xA:
0.0		 5xdxC-1f0xA:
17.74
5xdxJ-1f0xA:
6.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 5 LEU A  25
PHE A  51
LEU A  16
PHE A  12
 None
 1.18A 5xdxP-1f0xA:
undetectable
5xdxW-1f0xA:
0.0		 5xdxP-1f0xA:
17.74
5xdxW-1f0xA:
6.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 HIS A 496
HIS A 489
ARG A 242
 None
FAD  A 600 ( 4.6A)
None
 1.09A 6b58A-1f0xA:
undetectable		 6b58A-1f0xA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 LEU A  73
VAL A  49
LEU A  26
VAL A  96
ILE A  98
 None
 1.12A 6dgxB-1f0xA:
undetectable		 6dgxB-1f0xA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		4 / 5 ARG A  34
ALA A  33
GLN A  75
ILE A  98
 None
 1.42A 6g9bA-1f0xA:
0.0
6g9bB-1f0xA:
0.0		 6g9bA-1f0xA:
9.93
6g9bB-1f0xA:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1f0x D-LACTATE
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 ARG A 233
PHE A 490
PHE A 300
 None
 1.03A 6nknC-1f0xA:
0.1
6nknJ-1f0xA:
0.0		 6nknC-1f0xA:
17.79
6nknJ-1f0xA:
6.30