SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f15'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IGX_A_EPAA700_2 (PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1)	1f15	COAT PROTEIN (Cucumber mosaic virus)	4 / 8	TYR A 86 VAL A 187 ILE A 109 LEU A 199	None	0.91A	1igxA-1f15A: undetectable	1igxA-1f15A: 16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KAW_A_SUZA91_1 (SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1)	1f15	COAT PROTEIN (Cucumber mosaic virus)	5 / 11	LEU A 107 ILE A 205 SER A 72 ILE A 73 VAL A 125	None	0.96A	2kawA-1f15A: undetectable	2kawA-1f15A: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JQ4_B_IMNB401_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2)	1f15	COAT PROTEIN (Cucumber mosaic virus)	5 / 10	HIS A 202 VAL A 185 ASN A 112 LEU A 114 LEU A 199	None	1.45A	4jq4B-1f15A: undetectable	4jq4B-1f15A: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JQ4_B_IMNB401_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2)	1f15	COAT PROTEIN (Cucumber mosaic virus)	5 / 10	TYR A 86 VAL A 123 ILE A 109 LEU A 91 LEU A 90	None	1.21A	4jq4B-1f15A: undetectable	4jq4B-1f15A: 21.13

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IGX_A_EPAA700_2","PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1","1f15","COAT PROTEIN","Cucumber mosaic virus",4,"TYR A  86;VAL A 187;ILE A 109;LEU A 199","None","0.91A","1igxA-1f15A:undetectable","1igxA-1f15A:16.72"],["2KAW_A_SUZA91_1","SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1","1f15","COAT PROTEIN","Cucumber mosaic virus",5,"LEU A 107;ILE A 205;SER A  72;ILE A  73;VAL A 125","None","0.96A","2kawA-1f15A:undetectable","2kawA-1f15A:16.67"],["4JQ4_B_IMNB401_1","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","1f15","COAT PROTEIN","Cucumber mosaic virus",5,"HIS A 202;VAL A 185;ASN A 112;LEU A 114;LEU A 199","None","1.45A","4jq4B-1f15A:undetectable","4jq4B-1f15A:21.13"],["4JQ4_B_IMNB401_1","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","1f15","COAT PROTEIN","Cucumber mosaic virus",5,"TYR A  86;VAL A 123;ILE A 109;LEU A  91;LEU A  90","None","1.21A","4jq4B-1f15A:undetectable","4jq4B-1f15A:21.13"]]