SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f1c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)
1f1c CYTOCHROME C549
(Arthrospira
maxima)
4 / 7 LYS A  27
LYS A  28
TYR A 118
LEU A 112
None
0.88A 4yv5A-1f1cA:
0.0
4yv5A-1f1cA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)
1f1c CYTOCHROME C549
(Arthrospira
maxima)
4 / 7 LYS A  27
LYS A  28
TYR A 118
LEU A 112
None
0.91A 4yv5B-1f1cA:
0.0
4yv5B-1f1cA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)
1f1c CYTOCHROME C549
(Arthrospira
maxima)
3 / 3 ASN A  49
ASP A  83
GLY A  84
HEM  A 200 ( 4.8A)
None
None
0.56A 5fctB-1f1cA:
undetectable
5fctB-1f1cA:
20.41