SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f1m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 1f1m OUTER SURFACE
PROTEIN C
(Borreliella
burgdorferi) 		4 / 6 LEU A 191
VAL A 195
LYS A 196
ILE A  49
 None
 0.88A 2piwA-1f1mA:
0.2		 2piwA-1f1mA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1f1m OUTER SURFACE
PROTEIN C
(Borreliella
burgdorferi) 		5 / 12 GLY A  94
SER A  98
ILE A  76
GLY A  77
ASN A 154
 None
 1.25A 4obwC-1f1mA:
undetectable		 4obwC-1f1mA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_C_PPFC601_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1f1m OUTER SURFACE
PROTEIN C
(Borreliella
burgdorferi) 		4 / 6 ASP A 152
GLY A  77
ASP A  91
LYS A 156
 None
 1.41A 5hp1C-1f1mA:
0.0		 5hp1C-1f1mA:
16.73