SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f1u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 7 GLU A 267
ARG A 152
THR A 198
VAL A 199
ALA A 216
 MN  A 500 (-2.8A)
None
None
None
MN  A 500 ( 4.5A)
 1.35A 1fo4B-1f1uA:
undetectable		 1fo4B-1f1uA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		3 / 3 THR A   7
GLU A 171
ASP A 180
 None
 0.84A 1nt2A-1f1uA:
0.2		 1nt2A-1f1uA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 12 GLY A 174
ASP A 172
ASP A  14
PRO A  13
PHE A 128
 None
 1.03A 2f8lA-1f1uA:
undetectable		 2f8lA-1f1uA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 11 ARG A 165
LEU A 122
ASP A 201
ILE A  15
GLY A 174
 None
 1.11A 2o4pA-1f1uA:
undetectable		 2o4pA-1f1uA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		4 / 7 ALA A 253
TYR A 269
TYR A 257
HIS A 248
 None
 1.29A 2pncA-1f1uA:
undetectable		 2pncA-1f1uA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		4 / 8 ASP A 272
ASP A 154
SER A 251
HIS A 248
 None
 0.88A 2q0iA-1f1uA:
undetectable		 2q0iA-1f1uA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 9 GLU A 267
ARG A 152
THR A 198
VAL A 199
ALA A 216
 MN  A 500 (-2.8A)
None
None
None
MN  A 500 ( 4.5A)
 1.40A 3ax7B-1f1uA:
0.0		 3ax7B-1f1uA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		4 / 6 THR A 198
VAL A 199
GLU A 267
SER A 251
 None
None
MN  A 500 (-2.8A)
None
 1.20A 3b6rB-1f1uA:
undetectable		 3b6rB-1f1uA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 11 ARG A 165
LEU A 122
ASP A 201
ILE A  15
GLY A 174
 None
 1.13A 3spkA-1f1uA:
undetectable		 3spkA-1f1uA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		4 / 8 VAL A 116
TYR A  79
LEU A 173
TYR A  93
 None
 1.11A 3v81A-1f1uA:
0.0		 3v81A-1f1uA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 12 LEU A  64
THR A 219
SER A  55
ILE A  23
LEU A 256
 None
 1.45A 3vw1B-1f1uA:
0.0		 3vw1B-1f1uA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		4 / 7 ASP A 313
GLN A 319
ASN A 317
ILE A  71
 None
 1.23A 4ii8A-1f1uA:
undetectable		 4ii8A-1f1uA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 11 HIS A 214
TYR A 257
GLU A 267
HIS A 155
ALA A 203
 MN  A 500 (-3.2A)
None
MN  A 500 (-2.8A)
MN  A 500 (-3.4A)
None
 0.66A 4ir0A-1f1uA:
7.4
4ir0B-1f1uA:
7.6		 4ir0A-1f1uA:
20.31
4ir0B-1f1uA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 11 HIS A 155
ALA A 203
HIS A 214
TYR A 257
GLU A 267
 MN  A 500 (-3.4A)
None
MN  A 500 (-3.2A)
None
MN  A 500 (-2.8A)
 0.61A 4ir0A-1f1uA:
7.4
4ir0B-1f1uA:
7.6		 4ir0A-1f1uA:
20.31
4ir0B-1f1uA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 12 HIS A 214
TYR A 257
GLU A 267
HIS A 155
ALA A 203
 MN  A 500 (-3.2A)
None
MN  A 500 (-2.8A)
MN  A 500 (-3.4A)
None
 0.60A 4jd1A-1f1uA:
7.4
4jd1B-1f1uA:
7.4		 4jd1A-1f1uA:
20.31
4jd1B-1f1uA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 12 HIS A 155
ALA A 203
HIS A 214
TYR A 257
GLU A 267
 MN  A 500 (-3.4A)
None
MN  A 500 (-3.2A)
None
MN  A 500 (-2.8A)
 0.72A 4jd1A-1f1uA:
7.4
4jd1B-1f1uA:
7.4		 4jd1A-1f1uA:
20.31
4jd1B-1f1uA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		3 / 3 ASP A 260
LEU A  39
VAL A  43
 None
 0.72A 4jecB-1f1uA:
0.0		 4jecB-1f1uA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 12 HIS A 214
TYR A 257
GLU A 267
HIS A 155
ALA A 203
 MN  A 500 (-3.2A)
None
MN  A 500 (-2.8A)
MN  A 500 (-3.4A)
None
 0.58A 4jh3A-1f1uA:
7.3
4jh3B-1f1uA:
7.6		 4jh3A-1f1uA:
19.20
4jh3B-1f1uA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 11 HIS A 155
ALA A 203
HIS A 214
TYR A 257
GLU A 267
 MN  A 500 (-3.4A)
None
MN  A 500 (-3.2A)
None
MN  A 500 (-2.8A)
 0.56A 4jh3A-1f1uA:
7.3
4jh3B-1f1uA:
7.6		 4jh3A-1f1uA:
19.20
4jh3B-1f1uA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 11 HIS A 214
TYR A 257
GLU A 267
HIS A 155
ALA A 203
 MN  A 500 (-3.2A)
None
MN  A 500 (-2.8A)
MN  A 500 (-3.4A)
None
 0.49A 4jh4A-1f1uA:
7.5
4jh4B-1f1uA:
7.3		 4jh4A-1f1uA:
19.20
4jh4B-1f1uA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 11 HIS A 155
ALA A 203
HIS A 214
TYR A 257
GLU A 267
 MN  A 500 (-3.4A)
None
MN  A 500 (-3.2A)
None
MN  A 500 (-2.8A)
 0.52A 4jh4A-1f1uA:
7.5
4jh4B-1f1uA:
7.3		 4jh4A-1f1uA:
19.20
4jh4B-1f1uA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 11 HIS A 214
TYR A 257
GLU A 267
HIS A 155
ALA A 203
 MN  A 500 (-3.2A)
None
MN  A 500 (-2.8A)
MN  A 500 (-3.4A)
None
 0.55A 4jh5A-1f1uA:
7.5
4jh5B-1f1uA:
7.3		 4jh5A-1f1uA:
19.20
4jh5B-1f1uA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 11 HIS A 155
ALA A 203
HIS A 214
TYR A 257
GLU A 267
 MN  A 500 (-3.4A)
None
MN  A 500 (-3.2A)
None
MN  A 500 (-2.8A)
 0.56A 4jh5A-1f1uA:
7.5
4jh5B-1f1uA:
7.3		 4jh5A-1f1uA:
19.20
4jh5B-1f1uA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 10 HIS A 214
TYR A 257
GLU A 267
HIS A 155
ALA A 203
 MN  A 500 (-3.2A)
None
MN  A 500 (-2.8A)
MN  A 500 (-3.4A)
None
 0.58A 4jh6A-1f1uA:
7.6
4jh6B-1f1uA:
7.4		 4jh6A-1f1uA:
19.20
4jh6B-1f1uA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 10 HIS A 155
ALA A 203
HIS A 214
TYR A 257
GLU A 267
 MN  A 500 (-3.4A)
None
MN  A 500 (-3.2A)
None
MN  A 500 (-2.8A)
 0.58A 4jh6A-1f1uA:
7.6
4jh6B-1f1uA:
7.4		 4jh6A-1f1uA:
19.20
4jh6B-1f1uA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 10 HIS A 214
TYR A 257
GLU A 267
HIS A 155
ALA A 203
 MN  A 500 (-3.2A)
None
MN  A 500 (-2.8A)
MN  A 500 (-3.4A)
None
 0.56A 4jh8A-1f1uA:
7.5
4jh8B-1f1uA:
7.3		 4jh8A-1f1uA:
19.20
4jh8B-1f1uA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		5 / 10 HIS A 155
ALA A 203
HIS A 214
TYR A 257
GLU A 267
 MN  A 500 (-3.4A)
None
MN  A 500 (-3.2A)
None
MN  A 500 (-2.8A)
 0.56A 4jh8A-1f1uA:
7.5
4jh8B-1f1uA:
7.3		 4jh8A-1f1uA:
19.20
4jh8B-1f1uA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		4 / 7 GLU A  22
ARG A 117
GLU A 127
ALA A  78
 None
 0.96A 4zz8A-1f1uA:
0.0		 4zz8A-1f1uA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		3 / 3 THR A 109
HIS A 155
LEU A 153
 None
MN  A 500 (-3.4A)
None
 0.75A 5axdA-1f1uA:
undetectable		 5axdA-1f1uA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		3 / 3 THR A 109
HIS A 155
LEU A 153
 None
MN  A 500 (-3.4A)
None
 0.75A 5axdC-1f1uA:
0.0		 5axdC-1f1uA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		4 / 6 GLY A 249
ASP A 154
ILE A 268
TYR A 257
 None
 1.02A 5iwuA-1f1uA:
undetectable		 5iwuA-1f1uA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		3 / 3 TYR A  35
LEU A  28
ASP A  47
 None
 0.79A 5zv2B-1f1uA:
undetectable		 5zv2B-1f1uA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		4 / 6 GLY A 166
GLN A 158
TYR A 126
TYR A 169
 None
 1.22A 6ag0A-1f1uA:
undetectable		 6ag0A-1f1uA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 1f1u HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Arthrobacter
globiformis) 		4 / 6 GLY A 166
GLN A 158
TYR A 126
TYR A 169
 None
 1.24A 6ag0C-1f1uA:
undetectable		 6ag0C-1f1uA:
13.27