SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f1z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 1f1z TNSA ENDONUCLEASE
(Escherichia
coli) 		4 / 4 HIS A  50
LEU A 202
LEU A 198
LEU A 191
 None
 1.25A 1a4lD-1f1zA:
undetectable		 1a4lD-1f1zA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1f1z TNSA ENDONUCLEASE
(Escherichia
coli) 		4 / 7 THR A 236
PHE A 243
SER A 230
LEU A  64
 None
 1.09A 1qcaA-1f1zA:
0.0		 1qcaA-1f1zA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 1f1z TNSA ENDONUCLEASE
(Escherichia
coli) 		4 / 8 ARG A  54
GLU A  81
LEU A  77
VAL A  76
 None
 0.89A 2bxgA-1f1zA:
undetectable		 2bxgA-1f1zA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1f1z TNSA ENDONUCLEASE
(Escherichia
coli) 		3 / 3 LEU A 148
TRP A  32
TYR A 152
 None
 1.01A 3aicB-1f1zA:
undetectable		 3aicB-1f1zA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1f1z TNSA ENDONUCLEASE
(Escherichia
coli) 		3 / 3 LEU A 148
TRP A  32
TYR A 152
 None
 1.01A 3aicE-1f1zA:
undetectable		 3aicE-1f1zA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1f1z TNSA ENDONUCLEASE
(Escherichia
coli) 		3 / 3 LEU A 148
TRP A  32
TYR A 152
 None
 1.00A 3aicF-1f1zA:
undetectable		 3aicF-1f1zA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1f1z TNSA ENDONUCLEASE
(Escherichia
coli) 		3 / 3 LEU A 148
TRP A  32
TYR A 152
 None
 1.00A 3aicG-1f1zA:
undetectable		 3aicG-1f1zA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1f1z TNSA ENDONUCLEASE
(Escherichia
coli) 		3 / 3 LEU A 148
TRP A  32
TYR A 152
 None
 1.00A 3aicH-1f1zA:
undetectable		 3aicH-1f1zA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1f1z TNSA ENDONUCLEASE
(Escherichia
coli) 		3 / 3 ARG A  54
HIS A  56
TYR A  29
 None
 0.99A 4fu8A-1f1zA:
0.0		 4fu8A-1f1zA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1f1z TNSA ENDONUCLEASE
(Escherichia
coli) 		3 / 3 ARG A  54
HIS A  56
TYR A  29
 None
 0.96A 4fu9A-1f1zA:
0.0		 4fu9A-1f1zA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 1f1z TNSA ENDONUCLEASE
(Escherichia
coli) 		3 / 3 LYS A 183
ARG A 233
TRP A 178
 None
 0.95A 4i90A-1f1zA:
0.1		 4i90A-1f1zA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1f1z TNSA ENDONUCLEASE
(Escherichia
coli) 		5 / 9 LEU A 235
THR A 236
ILE A 210
PHE A 249
ILE A 259
 None
 1.24A 6ebpA-1f1zA:
undetectable		 6ebpA-1f1zA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1f1z TNSA ENDONUCLEASE
(Escherichia
coli) 		5 / 10 LEU A 235
THR A 236
ILE A 210
PHE A 249
ILE A 259
 None
 1.21A 6ebpB-1f1zA:
undetectable		 6ebpB-1f1zA:
16.15