SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f2i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 1f2i FUSION OF N-TERMINAL
17-MER PEPTIDE
EXTENSION TO ZIF12
(Mus
musculus) 		4 / 5 HIS G1153
CYH G1137
ILE G1139
HIS G1157
 ZN  G1202 (-3.3A)
ZN  G1202 (-2.4A)
ZN  G1202 ( 4.6A)
ZN  G1202 (-3.3A)
 1.42A 3qpkA-1f2iG:
undetectable		 3qpkA-1f2iG:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB601_0
(LACCASE-1)		 1f2i FUSION OF N-TERMINAL
17-MER PEPTIDE
EXTENSION TO ZIF12
(Mus
musculus) 		4 / 4 HIS G1153
CYH G1137
ILE G1139
HIS G1157
 ZN  G1202 (-3.3A)
ZN  G1202 (-2.4A)
ZN  G1202 ( 4.6A)
ZN  G1202 (-3.3A)
 1.41A 3qpkB-1f2iG:
undetectable		 3qpkB-1f2iG:
8.74