SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f2r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1f2r INHIBITOR OF
CASPASE-ACTIVATED
DNASE
(Mus
musculus) 		4 / 7 LEU I  23
GLN I  31
LEU I  42
PHE I  76
 None
 1.05A 1v55P-1f2rI:
undetectable
1v55W-1f2rI:
0.0		 1v55P-1f2rI:
17.97
1v55W-1f2rI:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1f2r INHIBITOR OF
CASPASE-ACTIVATED
DNASE
(Mus
musculus) 		4 / 7 LEU I  23
GLN I  31
LEU I  42
PHE I  76
 None
 1.06A 2dysP-1f2rI:
undetectable
2dysW-1f2rI:
undetectable		 2dysP-1f2rI:
17.97
2dysW-1f2rI:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1f2r INHIBITOR OF
CASPASE-ACTIVATED
DNASE
(Mus
musculus) 		4 / 7 LEU I  23
GLN I  31
LEU I  42
PHE I  76
 None
 0.98A 2eijC-1f2rI:
undetectable
2eijJ-1f2rI:
0.0		 2eijC-1f2rI:
17.97
2eijJ-1f2rI:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1f2r INHIBITOR OF
CASPASE-ACTIVATED
DNASE
(Mus
musculus) 		4 / 7 LEU I  23
GLN I  31
LEU I  42
PHE I  76
 None
 1.00A 2eijP-1f2rI:
undetectable
2eijW-1f2rI:
0.0		 2eijP-1f2rI:
17.97
2eijW-1f2rI:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1f2r INHIBITOR OF
CASPASE-ACTIVATED
DNASE
(Mus
musculus) 		4 / 7 LEU I  23
GLN I  31
LEU I  42
PHE I  76
 None
 0.96A 2eimC-1f2rI:
undetectable
2eimJ-1f2rI:
0.0		 2eimC-1f2rI:
17.97
2eimJ-1f2rI:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1f2r INHIBITOR OF
CASPASE-ACTIVATED
DNASE
(Mus
musculus) 		4 / 7 LEU I  23
GLN I  31
LEU I  42
PHE I  76
 None
 1.02A 2einC-1f2rI:
undetectable
2einJ-1f2rI:
0.0		 2einC-1f2rI:
17.97
2einJ-1f2rI:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1f2r INHIBITOR OF
CASPASE-ACTIVATED
DNASE
(Mus
musculus) 		4 / 6 LEU I  23
GLN I  31
LEU I  42
PHE I  76
 None
 1.03A 2einP-1f2rI:
undetectable
2einW-1f2rI:
0.0		 2einP-1f2rI:
17.97
2einW-1f2rI:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 1f2r CASPASE-ACTIVATED
DNASE
INHIBITOR OF
CASPASE-ACTIVATED
DNASE
(Mus
musculus) 		3 / 3 ARG C  14
GLU I  65
SER C  18
 None
 0.89A 2xkkA-1f2rC:
undetectable
2xkkC-1f2rC:
undetectable		 2xkkA-1f2rC:
7.49
2xkkC-1f2rC:
7.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1f2r INHIBITOR OF
CASPASE-ACTIVATED
DNASE
(Mus
musculus) 		4 / 6 LEU I  23
GLN I  31
LEU I  42
PHE I  76
 None
 0.99A 2zxwP-1f2rI:
undetectable
2zxwW-1f2rI:
undetectable		 2zxwP-1f2rI:
17.97
2zxwW-1f2rI:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 1f2r INHIBITOR OF
CASPASE-ACTIVATED
DNASE
(Mus
musculus) 		4 / 5 LEU I  42
SER I  44
LEU I  49
LEU I  61
 None
 1.30A 4n09D-1f2rI:
undetectable		 4n09D-1f2rI:
14.57