SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f3b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 1f3b GLUTATHIONE
S-TRANSFERASE YA
CHAIN
(Mus
musculus) 		4 / 7 TYR A   8
PHE A   9
GLY A  13
ARG A  14
 GBX  A 223 (-4.9A)
GBX  A 223 (-3.7A)
GBX  A 223 ( 4.5A)
GBX  A 223 (-3.8A)
 0.69A 11gsB-1f3bA:
23.6		 11gsB-1f3bA:
30.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1f3b GLUTATHIONE
S-TRANSFERASE YA
CHAIN
(Mus
musculus) 		3 / 3 THR A 127
LEU A 132
LEU A 139
 None
 0.66A 1mz9C-1f3bA:
undetectable		 1mz9C-1f3bA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1f3b GLUTATHIONE
S-TRANSFERASE YA
CHAIN
(Mus
musculus) 		4 / 7 LYS A 194
LEU A 197
GLN A 198
LEU A 164
 None
 1.01A 1v55P-1f3bA:
3.5
1v55W-1f3bA:
0.0		 1v55P-1f3bA:
16.67
1v55W-1f3bA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1f3b GLUTATHIONE
S-TRANSFERASE YA
CHAIN
(Mus
musculus) 		3 / 3 LEU A 159
PHE A 135
ARG A  68
 None
 0.85A 1xdkB-1f3bA:
0.0		 1xdkB-1f3bA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1f3b GLUTATHIONE
S-TRANSFERASE YA
CHAIN
(Mus
musculus) 		3 / 3 LEU A 159
PHE A 135
ARG A  68
 None
 0.84A 1xdkF-1f3bA:
0.0		 1xdkF-1f3bA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1f3b GLUTATHIONE
S-TRANSFERASE YA
CHAIN
(Mus
musculus) 		4 / 5 LEU A  71
GLY A  26
ALA A  75
ILE A  74
 None
 0.80A 2aohB-1f3bA:
undetectable		 2aohB-1f3bA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1f3b GLUTATHIONE
S-TRANSFERASE YA
CHAIN
(Mus
musculus) 		4 / 7 LYS A 194
LEU A 197
GLN A 198
LEU A 164
 None
 0.99A 2eijP-1f3bA:
3.5
2eijW-1f3bA:
0.0		 2eijP-1f3bA:
16.67
2eijW-1f3bA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1f3b GLUTATHIONE
S-TRANSFERASE YA
CHAIN
(Mus
musculus) 		5 / 11 HIS A 142
GLU A  87
VAL A 138
GLY A  82
ILE A  91
 None
 1.23A 2uxpB-1f3bA:
0.0		 2uxpB-1f3bA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 1f3b GLUTATHIONE
S-TRANSFERASE YA
CHAIN
(Mus
musculus) 		3 / 3 ARG A  12
ARG A  19
PRO A 205
 None
 1.11A 2wljA-1f3bA:
3.0		 2wljA-1f3bA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1f3b GLUTATHIONE
S-TRANSFERASE YA
CHAIN
(Mus
musculus) 		4 / 8 LYS A 194
LEU A 197
GLN A 198
LEU A 164
 None
 0.98A 3asoC-1f3bA:
3.4
3asoJ-1f3bA:
0.0		 3asoC-1f3bA:
16.67
3asoJ-1f3bA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 1f3b GLUTATHIONE
S-TRANSFERASE YA
CHAIN
(Mus
musculus) 		3 / 3 ASP A 156
GLU A  87
SER A 189
 None
 0.86A 3p2kA-1f3bA:
undetectable		 3p2kA-1f3bA:
21.09