SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f3g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		5 / 9 PHE A  77
VAL A 138
ILE A  22
VAL A  63
ILE A  79
 None
 1.39A 1gebA-1f3gA:
undetectable		 1gebA-1f3gA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		5 / 11 LEU A  26
GLY A 159
ASP A 117
VAL A 119
ILE A  22
 None
 1.00A 1hxwB-1f3gA:
undetectable		 1hxwB-1f3gA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		4 / 6 VAL A 113
VAL A 163
ILE A 140
ILE A  50
 None
 0.82A 1uwhA-1f3gA:
undetectable		 1uwhA-1f3gA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		4 / 6 VAL A 113
VAL A 163
ILE A 140
ILE A  50
 None
 0.81A 1uwhB-1f3gA:
undetectable		 1uwhB-1f3gA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		5 / 11 PRO A  54
THR A 136
GLY A  92
THR A  95
LEU A 124
 None
 1.40A 2uvnB-1f3gA:
undetectable		 2uvnB-1f3gA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		5 / 9 LEU A  26
GLY A 159
ASP A 117
VAL A 119
ILE A  22
 None
 1.05A 3ektA-1f3gA:
undetectable		 3ektA-1f3gA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		5 / 9 LEU A  26
GLY A 159
ASP A 117
VAL A 119
ILE A  22
 None
 1.02A 4dqcB-1f3gA:
undetectable		 4dqcB-1f3gA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		4 / 6 PHE A  91
ILE A  52
PRO A  25
PHE A 122
 None
 1.25A 4fgkA-1f3gA:
undetectable		 4fgkA-1f3gA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		5 / 10 LEU A  26
GLY A 159
ASP A 117
VAL A 119
ILE A  22
 None
 1.03A 4njtB-1f3gA:
undetectable		 4njtB-1f3gA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		5 / 9 LEU A  26
GLY A 159
ASP A 117
VAL A 119
ILE A  22
 None
 1.06A 4njtD-1f3gA:
undetectable		 4njtD-1f3gA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		5 / 8 ILE A 120
VAL A 119
ILE A 140
ILE A  20
ILE A 164
 None
 1.23A 5hi2A-1f3gA:
undetectable		 5hi2A-1f3gA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		5 / 9 LEU A  26
GLY A 159
ASP A 117
VAL A 119
ILE A  22
 None
 1.01A 5kr0B-1f3gA:
undetectable		 5kr0B-1f3gA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_0
(TETRACYCLINE
DESTRUCTASE TET(50))		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		5 / 12 GLY A 154
THR A  55
GLY A  56
VAL A 138
ILE A  50
 None
 1.18A 5tuiB-1f3gA:
undetectable		 5tuiB-1f3gA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		5 / 8 GLY A  28
LEU A  87
VAL A 138
ILE A  30
GLY A 154
 None
 1.22A 5vkqB-1f3gA:
undetectable
5vkqC-1f3gA:
undetectable		 5vkqB-1f3gA:
7.58
5vkqC-1f3gA:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC
(Escherichia
coli) 		5 / 12 VAL A 113
GLY A  65
SER A  81
PHE A  77
VAL A  89
 None
 1.30A 6a94A-1f3gA:
undetectable		 6a94A-1f3gA:
19.40