SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICR_A_NIOA604_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1f3j	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN (Mus musculus)	4 / 5	THR A 41 PHE A 54 GLU A 55 GLY A 58	None	1.04A	1icrA-1f3jA: 0.0 1icrB-1f3jA: undetectable	1icrA-1f3jA: 17.12 1icrB-1f3jA: 17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICR_B_NIOB602_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1f3j	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN (Mus musculus)	4 / 5	GLU A 55 GLY A 58 THR A 41 PHE A 54	None	1.02A	1icrA-1f3jA: 0.0 1icrB-1f3jA: undetectable	1icrA-1f3jA: 17.12 1icrB-1f3jA: 17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICU_A_NIOA221_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1f3j	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN (Mus musculus)	4 / 6	THR A 41 PHE A 54 GLU A 55 GLY A 58	None	1.00A	1icuA-1f3jA: 0.0 1icuB-1f3jA: 0.0	1icuA-1f3jA: 17.12 1icuB-1f3jA: 17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICU_B_NIOB219_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1f3j	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN (Mus musculus)	4 / 6	GLU A 55 GLY A 58 THR A 41 PHE A 54	None	1.08A	1icuA-1f3jA: 0.0 1icuB-1f3jA: 0.0	1icuA-1f3jA: 17.12 1icuB-1f3jA: 17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICU_C_NIOC225_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1f3j	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN (Mus musculus)	4 / 6	THR A 41 PHE A 54 GLU A 55 GLY A 58	None	1.00A	1icuC-1f3jA: 0.0 1icuD-1f3jA: 0.0	1icuC-1f3jA: 17.12 1icuD-1f3jA: 17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICV_C_NIOC708_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1f3j	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN (Mus musculus)	4 / 5	THR A 41 PHE A 54 GLU A 55 GLY A 58	None	0.99A	1icvC-1f3jA: 0.0 1icvD-1f3jA: 0.0	1icvC-1f3jA: 17.12 1icvD-1f3jA: 17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICV_D_NIOD706_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1f3j	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN (Mus musculus)	4 / 5	GLU A 55 GLY A 58 THR A 41 PHE A 54	None	0.99A	1icvC-1f3jA: 0.0 1icvD-1f3jA: 0.0	1icvC-1f3jA: 17.12 1icvD-1f3jA: 17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQB_B_BEZB525_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1f3j	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN (Mus musculus)	4 / 5	GLU A 55 GLY A 58 THR A 41 PHE A 54	None	1.09A	1kqbA-1f3jA: 0.0 1kqbB-1f3jA: 0.0	1kqbA-1f3jA: 19.17 1kqbB-1f3jA: 19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQB_C_BEZC522_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1f3j	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN (Mus musculus)	4 / 6	THR A 41 PHE A 54 GLU A 55 GLY A 58	None	1.14A	1kqbC-1f3jA: 0.0 1kqbD-1f3jA: 0.0	1kqbC-1f3jA: 19.17 1kqbD-1f3jA: 19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQB_D_BEZD523_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1f3j	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN (Mus musculus)	4 / 6	GLU A 55 GLY A 58 THR A 41 PHE A 54	None	1.00A	1kqbC-1f3jA: 0.0 1kqbD-1f3jA: 0.0	1kqbC-1f3jA: 19.17 1kqbD-1f3jA: 19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YV5_A_SVRA205_1 (BASIC PHOSPHOLIPASE A2 HOMOLOG 2)	1f3j	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN (Mus musculus)	4 / 7	ASN A 118 TYR A 150 LEU A 151 PHE A 153	NAG A1002 (-2.2A) None None None	1.16A	4yv5A-1f3jA: 0.0	4yv5A-1f3jA: 16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YV5_B_SVRB207_2 (BASIC PHOSPHOLIPASE A2 HOMOLOG 2)	1f3j	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN (Mus musculus)	4 / 7	ASN A 118 TYR A 150 LEU A 151 PHE A 153	NAG A1002 (-2.2A) None None None	1.25A	4yv5B-1f3jA: 0.0	4yv5B-1f3jA: 16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZB_C_ACTC401_0 (PROTON-GATED ION CHANNEL)	1f3j	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN (Mus musculus)	5 / 7	ILE A 112 PHE A 137 VAL A 109 ILE A 119 GLU A 134	None	1.48A	4zzbC-1f3jA: 4.0 4zzbD-1f3jA: 3.3	4zzbC-1f3jA: 18.87 4zzbD-1f3jA: 18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZC_A_ACTA401_0 (PROTON-GATED ION CHANNEL)	1f3j	H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN (Mus musculus)	4 / 6	ILE A 112 PHE A 137 ILE A 119 GLU A 134	None	1.11A	4zzcA-1f3jA: 2.8 4zzcB-1f3jA: 2.9	4zzcA-1f3jA: 18.87 4zzcB-1f3jA: 18.87

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ICR_A_NIOA604_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1f3j","H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN","Mus musculus",4,"THR A  41;PHE A  54;GLU A  55;GLY A  58","None","1.04A","1icrA-1f3jA:0.0;1icrB-1f3jA:undetectable","1icrA-1f3jA:17.12;1icrB-1f3jA:17.12"],["1ICR_B_NIOB602_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1f3j","H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN","Mus musculus",4,"GLU A  55;GLY A  58;THR A  41;PHE A  54","None","1.02A","1icrA-1f3jA:0.0;1icrB-1f3jA:undetectable","1icrA-1f3jA:17.12;1icrB-1f3jA:17.12"],["1ICU_A_NIOA221_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1f3j","H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN","Mus musculus",4,"THR A  41;PHE A  54;GLU A  55;GLY A  58","None","1.00A","1icuA-1f3jA:0.0;1icuB-1f3jA:0.0","1icuA-1f3jA:17.12;1icuB-1f3jA:17.12"],["1ICU_B_NIOB219_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1f3j","H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN","Mus musculus",4,"GLU A  55;GLY A  58;THR A  41;PHE A  54","None","1.08A","1icuA-1f3jA:0.0;1icuB-1f3jA:0.0","1icuA-1f3jA:17.12;1icuB-1f3jA:17.12"],["1ICU_C_NIOC225_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1f3j","H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN","Mus musculus",4,"THR A  41;PHE A  54;GLU A  55;GLY A  58","None","1.00A","1icuC-1f3jA:0.0;1icuD-1f3jA:0.0","1icuC-1f3jA:17.12;1icuD-1f3jA:17.12"],["1ICV_C_NIOC708_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1f3j","H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN","Mus musculus",4,"THR A  41;PHE A  54;GLU A  55;GLY A  58","None","0.99A","1icvC-1f3jA:0.0;1icvD-1f3jA:0.0","1icvC-1f3jA:17.12;1icvD-1f3jA:17.12"],["1ICV_D_NIOD706_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1f3j","H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN","Mus musculus",4,"GLU A  55;GLY A  58;THR A  41;PHE A  54","None","0.99A","1icvC-1f3jA:0.0;1icvD-1f3jA:0.0","1icvC-1f3jA:17.12;1icvD-1f3jA:17.12"],["1KQB_B_BEZB525_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1f3j","H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN","Mus musculus",4,"GLU A  55;GLY A  58;THR A  41;PHE A  54","None","1.09A","1kqbA-1f3jA:0.0;1kqbB-1f3jA:0.0","1kqbA-1f3jA:19.17;1kqbB-1f3jA:19.17"],["1KQB_C_BEZC522_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1f3j","H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN","Mus musculus",4,"THR A  41;PHE A  54;GLU A  55;GLY A  58","None","1.14A","1kqbC-1f3jA:0.0;1kqbD-1f3jA:0.0","1kqbC-1f3jA:19.17;1kqbD-1f3jA:19.17"],["1KQB_D_BEZD523_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1f3j","H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN","Mus musculus",4,"GLU A  55;GLY A  58;THR A  41;PHE A  54","None","1.00A","1kqbC-1f3jA:0.0;1kqbD-1f3jA:0.0","1kqbC-1f3jA:19.17;1kqbD-1f3jA:19.17"],["4YV5_A_SVRA205_1","BASIC PHOSPHOLIPASE A2 HOMOLOG 2","1f3j","H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN","Mus musculus",4,"ASN A 118;TYR A 150;LEU A 151;PHE A 153","NAG A1002 (-2.2A);None;None;None","1.16A","4yv5A-1f3jA:0.0","4yv5A-1f3jA:16.77"],["4YV5_B_SVRB207_2","BASIC PHOSPHOLIPASE A2 HOMOLOG 2","1f3j","H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN","Mus musculus",4,"ASN A 118;TYR A 150;LEU A 151;PHE A 153","NAG A1002 (-2.2A);None;None;None","1.25A","4yv5B-1f3jA:0.0","4yv5B-1f3jA:16.77"],["4ZZB_C_ACTC401_0","PROTON-GATED ION CHANNEL","1f3j","H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN","Mus musculus",5,"ILE A 112;PHE A 137;VAL A 109;ILE A 119;GLU A 134","None","1.48A","4zzbC-1f3jA:4.0;4zzbD-1f3jA:3.3","4zzbC-1f3jA:18.87;4zzbD-1f3jA:18.87"],["4ZZC_A_ACTA401_0","PROTON-GATED ION CHANNEL","1f3j","H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN","Mus musculus",4,"ILE A 112;PHE A 137;ILE A 119;GLU A 134","None","1.11A","4zzcA-1f3jA:2.8;4zzcB-1f3jA:2.9","4zzcA-1f3jA:18.87;4zzcB-1f3jA:18.87"]]