SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f3o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FM6_A_9CRA501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	1f3o	HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796 (Methanocaldococc us jannaschii)	5 / 12	ILE A 51 LEU A 168 ALA A 169 VAL A 62 LEU A 21	None	1.02A	1fm6A-1f3oA: undetectable	1fm6A-1f3oA: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N49_D_RITD401_2 (PROTEASE)	1f3o	HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796 (Methanocaldococc us jannaschii)	4 / 6	ASP A 83 GLY A 86 ILE A 167 ILE A 64	None	0.89A	1n49D-1f3oA: undetectable	1n49D-1f3oA: 18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BU8_A_TF4A1379_1 (PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2)	1f3o	HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796 (Methanocaldococc us jannaschii)	4 / 8	LEU A 168 ILE A 2 ILE A 85 ILE A 64	None	0.77A	2bu8A-1f3oA: undetectable	2bu8A-1f3oA: 19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_A_ACTA505_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	1f3o	HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796 (Methanocaldococc us jannaschii)	3 / 3	THR A 8 ASN A 23 GLU A 59	None	0.64A	3v4tA-1f3oA: 0.0 3v4tC-1f3oA: 0.0	3v4tA-1f3oA: 22.91 3v4tC-1f3oA: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JJK_A_FOLA601_0 (FORMATE--TETRAHYDROF OLATE LIGASE)	1f3o	HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796 (Methanocaldococc us jannaschii)	4 / 8	ASN A 103 ALA A 100 LEU A 134 LEU A 146	None	0.94A	4jjkA-1f3oA: undetectable	4jjkA-1f3oA: 17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M5C_E_TA1E502_1 (TUBULIN BETA-2B CHAIN)	1f3o	HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796 (Methanocaldococc us jannaschii)	5 / 10	ASP A 170 LEU A 94 ALA A 155 GLY A 174 LEU A 176	MG A 301 ( 4.5A) None None None None	1.24A	5m5cE-1f3oA: undetectable	5m5cE-1f3oA: 21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_B_PCFB1804_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	1f3o	HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796 (Methanocaldococc us jannaschii)	5 / 8	GLY A 174 LEU A 168 VAL A 88 ILE A 184 GLY A 181	None	1.05A	5vkqB-1f3oA: 0.0 5vkqC-1f3oA: 0.0	5vkqB-1f3oA: 8.95 5vkqC-1f3oA: 8.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FM6_A_9CRA501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","1f3o","HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796","Methanocaldococcus jannaschii",5,"ILE A  51;LEU A 168;ALA A 169;VAL A  62;LEU A  21","None","1.02A","1fm6A-1f3oA:undetectable","1fm6A-1f3oA:22.78"],["1N49_D_RITD401_2","PROTEASE","1f3o","HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796","Methanocaldococcus jannaschii",4,"ASP A  83;GLY A  86;ILE A 167;ILE A  64","None","0.89A","1n49D-1f3oA:undetectable","1n49D-1f3oA:18.14"],["2BU8_A_TF4A1379_1","PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2","1f3o","HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796","Methanocaldococcus jannaschii",4,"LEU A 168;ILE A   2;ILE A  85;ILE A  64","None","0.77A","2bu8A-1f3oA:undetectable","2bu8A-1f3oA:19.40"],["3V4T_A_ACTA505_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","1f3o","HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796","Methanocaldococcus jannaschii",3,"THR A   8;ASN A  23;GLU A  59","None","0.64A","3v4tA-1f3oA:0.0;3v4tC-1f3oA:0.0","3v4tA-1f3oA:22.91;3v4tC-1f3oA:22.91"],["4JJK_A_FOLA601_0","FORMATE--TETRAHYDROFOLATE LIGASE","1f3o","HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796","Methanocaldococcus jannaschii",4,"ASN A 103;ALA A 100;LEU A 134;LEU A 146","None","0.94A","4jjkA-1f3oA:undetectable","4jjkA-1f3oA:17.89"],["5M5C_E_TA1E502_1","TUBULIN BETA-2B CHAIN","1f3o","HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796","Methanocaldococcus jannaschii",5,"ASP A 170;LEU A  94;ALA A 155;GLY A 174;LEU A 176"," MG A 301 ( 4.5A);None;None;None;None","1.24A","5m5cE-1f3oA:undetectable","5m5cE-1f3oA:21.04"],["5VKQ_B_PCFB1804_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","1f3o","HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN MJ0796","Methanocaldococcus jannaschii",5,"GLY A 174;LEU A 168;VAL A  88;ILE A 184;GLY A 181","None","1.05A","5vkqB-1f3oA:0.0;5vkqC-1f3oA:0.0","5vkqB-1f3oA:8.95;5vkqC-1f3oA:8.95"]]