SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f3u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1f3u TRANSCRIPTION
INITIATION FACTOR
IIF, BETA SUBUNIT
TRANSCRIPTION
INITIATION FACTOR
IIF, ALPHA SUBUNIT
(Homo
sapiens;
Homo
sapiens) 		4 / 6 LEU B 100
LEU A 106
TRP B  42
PHE B  39
 None
 1.46A 1ru9H-1f3uB:
undetectable
1ru9L-1f3uB:
undetectable		 1ru9H-1f3uB:
21.00
1ru9L-1f3uB:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1f3u TRANSCRIPTION
INITIATION FACTOR
IIF, ALPHA SUBUNIT
TRANSCRIPTION
INITIATION FACTOR
IIF, BETA SUBUNIT
(Homo
sapiens) 		4 / 8 PHE B 146
LEU A   9
PHE B  31
MET B  29
 None
 0.70A 1wrlC-1f3uB:
undetectable
1wrlD-1f3uB:
undetectable		 1wrlC-1f3uB:
18.02
1wrlD-1f3uB:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1f3u TRANSCRIPTION
INITIATION FACTOR
IIF, ALPHA SUBUNIT
TRANSCRIPTION
INITIATION FACTOR
IIF, BETA SUBUNIT
(Homo
sapiens) 		4 / 6 VAL A  54
ILE B 126
ALA A 114
LEU A  85
 None
 0.82A 3kk6B-1f3uA:
0.0		 3kk6B-1f3uA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 1f3u TRANSCRIPTION
INITIATION FACTOR
IIF, BETA SUBUNIT
TRANSCRIPTION
INITIATION FACTOR
IIF, ALPHA SUBUNIT
(Homo
sapiens;
Homo
sapiens) 		4 / 6 ARG B  49
TYR B 144
PHE A  96
LEU A 104
 None
 1.25A 3tgvB-1f3uB:
0.6		 3tgvB-1f3uB:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_C_BEZC1_0
(HEME-BINDING PROTEIN
HUTZ)		 1f3u TRANSCRIPTION
INITIATION FACTOR
IIF, BETA SUBUNIT
TRANSCRIPTION
INITIATION FACTOR
IIF, ALPHA SUBUNIT
(Homo
sapiens;
Homo
sapiens) 		4 / 5 ARG B  49
TYR B 144
PHE A  96
LEU A 104
 None
 1.19A 3tgvC-1f3uB:
0.9		 3tgvC-1f3uB:
18.92