SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f3y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 1f3y DIADENOSINE
5',5'''-P1,P4-TETRAP
HOSPHATE HYDROLASE
(Lupinus
angustifolius) 		3 / 3 ALA A 104
VAL A  17
TRP A 107
 None
 0.81A 1gmkA-1f3yA:
undetectable
1gmkB-1f3yA:
undetectable		 1gmkA-1f3yA:
9.09
1gmkB-1f3yA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 1f3y DIADENOSINE
5',5'''-P1,P4-TETRAP
HOSPHATE HYDROLASE
(Lupinus
angustifolius) 		3 / 3 ALA A 104
VAL A  17
TRP A 107
 None
 0.95A 1gmkC-1f3yA:
undetectable
1gmkD-1f3yA:
undetectable		 1gmkC-1f3yA:
9.09
1gmkD-1f3yA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 1f3y DIADENOSINE
5',5'''-P1,P4-TETRAP
HOSPHATE HYDROLASE
(Lupinus
angustifolius) 		5 / 12 LEU A 121
ALA A  31
GLY A  45
VAL A 147
THR A 146
 None
 1.05A 3c6gA-1f3yA:
0.0		 3c6gA-1f3yA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 1f3y DIADENOSINE
5',5'''-P1,P4-TETRAP
HOSPHATE HYDROLASE
(Lupinus
angustifolius) 		4 / 5 ILE A 119
THR A  68
SER A  69
PHE A 112
 None
 0.96A 3snfA-1f3yA:
0.0		 3snfA-1f3yA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 1f3y DIADENOSINE
5',5'''-P1,P4-TETRAP
HOSPHATE HYDROLASE
(Lupinus
angustifolius) 		4 / 8 TRP A 134
GLU A 118
GLN A 115
GLY A 114
 None
 0.98A 4f93B-1f3yA:
undetectable		 4f93B-1f3yA:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 1f3y DIADENOSINE
5',5'''-P1,P4-TETRAP
HOSPHATE HYDROLASE
(Lupinus
angustifolius) 		3 / 3 TRP A 134
GLN A  44
THR A  65
 None
 0.86A 4m2xA-1f3yA:
0.0		 4m2xA-1f3yA:
23.38