SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f5q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WA2_B_SAMB1267_1 (NON-STRUCTURAL PROTEIN 5)	1f5q	GAMMA HERPESVIRUS CYCLIN (Murid gammaherpesvirus 4)	3 / 3	SER B 149 HIS B 201 ASP B 216	None	0.79A	2wa2B-1f5qB: undetectable	2wa2B-1f5qB: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OZW_A_KKKA413_1 (FLAVOHEMOGLOBIN)	1f5q	GAMMA HERPESVIRUS CYCLIN (Murid gammaherpesvirus 4)	4 / 8	ILE B 224 GLN B 231 ALA B 198 LEU B 197	None	0.73A	3ozwA-1f5qB: undetectable	3ozwA-1f5qB: 19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R3A_A_RBFA402_2 (BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2)	1f5q	GAMMA HERPESVIRUS CYCLIN (Murid gammaherpesvirus 4)	4 / 8	GLU B 89 ASN B 90 LEU B 129 GLY B 122	None	0.77A	4r3aA-1f5qB: undetectable	4r3aA-1f5qB: 22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I71_A_68PA701_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	1f5q	GAMMA HERPESVIRUS CYCLIN (Murid gammaherpesvirus 4)	5 / 12	ALA B 75 PHE B 44 LEU B 182 GLY B 37 VAL B 40	None	1.19A	5i71A-1f5qB: 0.0	5i71A-1f5qB: 18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I75_A_68PA701_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	1f5q	GAMMA HERPESVIRUS CYCLIN (Murid gammaherpesvirus 4)	5 / 12	ALA B 75 PHE B 44 LEU B 182 GLY B 37 VAL B 40	None	1.18A	5i75A-1f5qB: 0.0	5i75A-1f5qB: 18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE8_C_08JC602_1 (CYTOCHROME P450 3A4)	1f5q	GAMMA HERPESVIRUS CYCLIN (Murid gammaherpesvirus 4)	4 / 7	SER B 136 ALA B 98 ILE B 111 LEU B 116	None	0.97A	5te8C-1f5qB: 0.0	5te8C-1f5qB: 19.96

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2WA2_B_SAMB1267_1","NON-STRUCTURAL PROTEIN 5","1f5q","GAMMA HERPESVIRUS CYCLIN","Murid gammaherpesvirus 4",3,"SER B 149;HIS B 201;ASP B 216","None","0.79A","2wa2B-1f5qB:undetectable","2wa2B-1f5qB:21.99"],["3OZW_A_KKKA413_1","FLAVOHEMOGLOBIN","1f5q","GAMMA HERPESVIRUS CYCLIN","Murid gammaherpesvirus 4",4,"ILE B 224;GLN B 231;ALA B 198;LEU B 197","None","0.73A","3ozwA-1f5qB:undetectable","3ozwA-1f5qB:19.65"],["4R3A_A_RBFA402_2","BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2","1f5q","GAMMA HERPESVIRUS CYCLIN","Murid gammaherpesvirus 4",4,"GLU B  89;ASN B  90;LEU B 129;GLY B 122","None","0.77A","4r3aA-1f5qB:undetectable","4r3aA-1f5qB:22.07"],["5I71_A_68PA701_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","1f5q","GAMMA HERPESVIRUS CYCLIN","Murid gammaherpesvirus 4",5,"ALA B  75;PHE B  44;LEU B 182;GLY B  37;VAL B  40","None","1.19A","5i71A-1f5qB:0.0","5i71A-1f5qB:18.30"],["5I75_A_68PA701_1","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","1f5q","GAMMA HERPESVIRUS CYCLIN","Murid gammaherpesvirus 4",5,"ALA B  75;PHE B  44;LEU B 182;GLY B  37;VAL B  40","None","1.18A","5i75A-1f5qB:0.0","5i75A-1f5qB:18.30"],["5TE8_C_08JC602_1","CYTOCHROME P450 3A4","1f5q","GAMMA HERPESVIRUS CYCLIN","Murid gammaherpesvirus 4",4,"SER B 136;ALA B  98;ILE B 111;LEU B 116","None","0.97A","5te8C-1f5qB:0.0","5te8C-1f5qB:19.96"]]