SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f5t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 1f5t DIPHTHERIA TOXIN
REPRESSOR
(Corynebacterium
diphtheriae) 		3 / 3 ASP A1099
THR A1008
GLU A1105
 None
None
NI  A 251 (-2.6A)
 0.82A 2zifB-1f5tA:
undetectable		 2zifB-1f5tA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1f5t DIPHTHERIA TOXIN
REPRESSOR
(Corynebacterium
diphtheriae) 		4 / 6 VAL A1056
SER A1061
ARG A1029
ILE A1015
 None
 1.06A 5jw1B-1f5tA:
undetectable		 5jw1B-1f5tA:
12.35