SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f68'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 1f68 HISTONE
ACETYLTRANSFERASE
(Homo
sapiens) 		3 / 4 LYS A 745
ALA A 750
MET A 754
 None
 0.97A 1hk3A-1f68A:
undetectable		 1hk3A-1f68A:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1f68 HISTONE
ACETYLTRANSFERASE
(Homo
sapiens) 		4 / 8 GLU A 806
ASN A 808
ASN A 803
ILE A 801
 None
 1.19A 3kp6A-1f68A:
undetectable
3kp6B-1f68A:
undetectable		 3kp6A-1f68A:
17.65
3kp6B-1f68A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 1f68 HISTONE
ACETYLTRANSFERASE
(Homo
sapiens) 		4 / 6 PRO A 752
VAL A 757
TYR A 765
ASN A 808
 None
 0.80A 5pbeA-1f68A:
16.3		 5pbeA-1f68A:
29.01