SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f6b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 1f6b SAR1
(Cricetulus
griseus) 		5 / 12 LEU A 115
VAL A 100
GLU A 144
LEU A 147
ARG A 148
 None
None
None
None
SO4  A 405 (-3.2A)
 1.25A 2bxfA-1f6bA:
undetectable		 2bxfA-1f6bA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1f6b SAR1
(Cricetulus
griseus) 		4 / 7 MET A 177
ILE A 131
PHE A 151
GLU A 144
 None
 1.35A 2nsiA-1f6bA:
0.0
2nsiB-1f6bA:
0.0		 2nsiA-1f6bA:
17.05
2nsiB-1f6bA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1f6b SAR1
(Cricetulus
griseus) 		4 / 7 MET A 177
ILE A 131
PHE A 151
GLU A 144
 None
 1.32A 2nsiC-1f6bA:
0.0
2nsiD-1f6bA:
0.0		 2nsiC-1f6bA:
17.05
2nsiD-1f6bA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1f6b SAR1
(Cricetulus
griseus) 		4 / 7 PHE A 151
GLU A 144
MET A 177
ILE A 131
 None
 1.34A 2nsiC-1f6bA:
0.0
2nsiD-1f6bA:
0.0		 2nsiC-1f6bA:
17.05
2nsiD-1f6bA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1f6b SAR1
(Cricetulus
griseus) 		4 / 7 MET A 177
ILE A 131
PHE A 151
GLU A 144
 None
 1.46A 3e7gA-1f6bA:
0.0
3e7gB-1f6bA:
0.0		 3e7gA-1f6bA:
17.40
3e7gB-1f6bA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1f6b SAR1
(Cricetulus
griseus) 		4 / 8 PHE A 151
GLU A 144
MET A 177
ILE A 131
 None
 1.43A 3e7gC-1f6bA:
0.0
3e7gD-1f6bA:
undetectable		 3e7gC-1f6bA:
17.40
3e7gD-1f6bA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 1f6b SAR1
(Cricetulus
griseus) 		3 / 3 ILE A  96
VAL A 127
ARG A 171
 None
 0.73A 3p73A-1f6bA:
0.0		 3p73A-1f6bA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1f6b SAR1
(Cricetulus
griseus) 		4 / 8 PHE A 151
GLU A 144
MET A 177
ILE A 131
 None
 1.37A 4cx7A-1f6bA:
0.0
4cx7B-1f6bA:
0.0		 4cx7A-1f6bA:
17.05
4cx7B-1f6bA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1f6b SAR1
(Cricetulus
griseus) 		4 / 7 PHE A 151
GLU A 144
MET A 177
ILE A 131
 None
 1.30A 4cx7C-1f6bA:
0.0
4cx7D-1f6bA:
0.0		 4cx7C-1f6bA:
17.05
4cx7D-1f6bA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1f6b SAR1
(Cricetulus
griseus) 		4 / 7 PHE A 151
GLU A 144
MET A 177
ILE A 131
 None
 1.31A 4nosA-1f6bA:
0.0
4nosB-1f6bA:
0.0		 4nosA-1f6bA:
17.10
4nosB-1f6bA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1f6b SAR1
(Cricetulus
griseus) 		5 / 10 ILE A 129
ILE A 131
LEU A 132
ILE A  93
ASN A  94
 None
 1.33A 5vkqA-1f6bA:
undetectable
5vkqD-1f6bA:
undetectable		 5vkqA-1f6bA:
7.87
5vkqD-1f6bA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1f6b SAR1
(Cricetulus
griseus) 		5 / 10 ILE A  93
ASN A  94
ILE A 129
ILE A 131
LEU A 132
 None
 1.32A 5vkqA-1f6bA:
undetectable
5vkqB-1f6bA:
undetectable		 5vkqA-1f6bA:
7.87
5vkqB-1f6bA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1f6b SAR1
(Cricetulus
griseus) 		5 / 10 ILE A  93
ASN A  94
ILE A 129
ILE A 131
LEU A 132
 None
 1.32A 5vkqC-1f6bA:
undetectable
5vkqD-1f6bA:
undetectable		 5vkqC-1f6bA:
7.87
5vkqD-1f6bA:
7.87