SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f7c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		5 / 11 THR A 258
THR A 256
ALA A 260
GLY A 212
ALA A 207
 None
 1.07A 2f162-1f7cA:
undetectable		 2f162-1f7cA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		5 / 11 THR A 258
THR A 256
ALA A 260
GLY A 212
ALA A 207
 None
 1.08A 2f16N-1f7cA:
undetectable		 2f16N-1f7cA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2REZ_A_ACTA156_0
(MULTIFUNCTIONAL
CYCLASE-DEHYDRATASE-
3-O-METHYL
TRANSFERASE TCMN)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		4 / 7 GLU A 253
THR A 256
TRP A 252
ARG A 211
 None
 1.21A 2rezA-1f7cA:
undetectable		 2rezA-1f7cA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		4 / 5 GLN A 310
THR A 378
HIS A 298
HIS A 313
 None
 1.48A 3g1uC-1f7cA:
undetectable		 3g1uC-1f7cA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		5 / 12 THR A 258
THR A 256
ALA A 260
GLY A 212
ALA A 207
 None
 1.06A 3mg02-1f7cA:
undetectable
3mg0V-1f7cA:
undetectable		 3mg02-1f7cA:
19.26
3mg0V-1f7cA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		5 / 11 THR A 258
THR A 256
ALA A 260
GLY A 212
ALA A 207
 None
 1.07A 3mg0N-1f7cA:
undetectable		 3mg0N-1f7cA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		4 / 6 SER A 259
LEU A 261
THR A 263
ARG A 266
 None
 1.48A 3thrB-1f7cA:
undetectable		 3thrB-1f7cA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		4 / 7 LEU A 319
ILE A 297
ILE A 375
VAL A 301
 None
 0.84A 4ojbA-1f7cA:
0.0		 4ojbA-1f7cA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		5 / 12 THR A 258
THR A 256
ALA A 260
ALA A 207
THR A 210
 None
 1.26A 4qvnV-1f7cA:
undetectable
4qvnb-1f7cA:
undetectable		 4qvnV-1f7cA:
22.47
4qvnb-1f7cA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		5 / 12 THR A 258
THR A 256
ALA A 260
GLY A 212
ALA A 207
 None
 1.02A 4qvnV-1f7cA:
undetectable
4qvnb-1f7cA:
undetectable		 4qvnV-1f7cA:
22.47
4qvnb-1f7cA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		5 / 12 THR A 258
THR A 256
ALA A 260
ALA A 207
THR A 210
 None
 1.26A 4qvnH-1f7cA:
undetectable
4qvnN-1f7cA:
undetectable		 4qvnH-1f7cA:
22.47
4qvnN-1f7cA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		5 / 12 THR A 258
THR A 256
ALA A 260
GLY A 212
ALA A 207
 None
 1.02A 4qvnH-1f7cA:
undetectable
4qvnN-1f7cA:
undetectable		 4qvnH-1f7cA:
22.47
4qvnN-1f7cA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		4 / 8 GLU A 306
LEU A 315
VAL A 301
LEU A 304
 None
 0.86A 4r38B-1f7cA:
undetectable		 4r38B-1f7cA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		4 / 7 GLU A 370
ILE A 365
LEU A 261
MET A 316
 None
 0.87A 4xumA-1f7cA:
undetectable		 4xumA-1f7cA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		5 / 12 THR A 258
THR A 256
ALA A 260
GLY A 212
ALA A 207
 None
 1.04A 5lf7V-1f7cA:
undetectable
5lf7b-1f7cA:
undetectable		 5lf7V-1f7cA:
22.69
5lf7b-1f7cA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		5 / 12 THR A 258
THR A 256
ALA A 260
GLY A 212
ALA A 207
 None
 1.03A 5lf7H-1f7cA:
undetectable
5lf7N-1f7cA:
undetectable		 5lf7H-1f7cA:
22.69
5lf7N-1f7cA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		5 / 12 LEU A 345
PRO A 342
THR A 343
LEU A 265
PHE A 340
 None
 1.20A 5xxiA-1f7cA:
0.5		 5xxiA-1f7cA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		3 / 3 GLY A 223
THR A 256
GLU A 253
 None
 0.65A 6b58A-1f7cA:
undetectable		 6b58A-1f7cA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		5 / 12 THR A 258
THR A 256
ALA A 260
GLY A 212
ALA A 207
 None
 1.06A 6hwdV-1f7cA:
undetectable
6hwdb-1f7cA:
undetectable		 6hwdV-1f7cA:
17.33
6hwdb-1f7cA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 1f7c RHOGAP PROTEIN
(Gallus
gallus) 		5 / 12 THR A 258
THR A 256
ALA A 260
GLY A 212
ALA A 207
 None
 1.06A 6hwdH-1f7cA:
undetectable
6hwdN-1f7cA:
undetectable		 6hwdH-1f7cA:
17.33
6hwdN-1f7cA:
19.70