SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f80'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.49A 1dvxA-1f80A:
undetectable		 1dvxA-1f80A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.49A 1dvxB-1f80A:
0.0		 1dvxB-1f80A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 6 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.72A 1ictB-1f80A:
undetectable		 1ictB-1f80A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 6 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.59A 1tyrA-1f80A:
undetectable		 1tyrA-1f80A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		5 / 11 THR A  10
GLN A 113
ALA A  51
GLY A  52
ALA A  56
 None
 1.18A 2f16H-1f80A:
undetectable
2f16I-1f80A:
undetectable		 2f16H-1f80A:
19.20
2f16I-1f80A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		5 / 11 THR A  10
GLN A 113
ALA A  51
GLY A  52
ALA A  56
 None
 1.19A 2f16V-1f80A:
undetectable
2f16W-1f80A:
undetectable		 2f16V-1f80A:
19.20
2f16W-1f80A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 6 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.85A 3cfqA-1f80A:
undetectable		 3cfqA-1f80A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.85A 3cfqA-1f80A:
undetectable
3cfqB-1f80A:
undetectable		 3cfqA-1f80A:
19.40
3cfqB-1f80A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.75A 3d2tA-1f80A:
undetectable		 3d2tA-1f80A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		5 / 11 THR A  10
GLN A 113
ALA A  51
GLY A  52
ALA A  56
 None
 1.19A 3mg0H-1f80A:
0.0
3mg0I-1f80A:
undetectable		 3mg0H-1f80A:
19.20
3mg0I-1f80A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.73A 3ozkB-1f80A:
undetectable		 3ozkB-1f80A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.86A 4d7bA-1f80A:
undetectable		 4d7bA-1f80A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 8 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.78A 4ik7B-1f80A:
undetectable		 4ik7B-1f80A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 6 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.83A 4ikiB-1f80A:
undetectable		 4ikiB-1f80A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.84A 4ikjA-1f80A:
undetectable
4ikjB-1f80A:
undetectable		 4ikjA-1f80A:
24.24
4ikjB-1f80A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 8 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.83A 4ikjA-1f80A:
0.0
4ikjB-1f80A:
undetectable		 4ikjA-1f80A:
24.24
4ikjB-1f80A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 8 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.85A 4ikkA-1f80A:
undetectable
4ikkB-1f80A:
undetectable		 4ikkA-1f80A:
24.24
4ikkB-1f80A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.87A 4ikkA-1f80A:
undetectable
4ikkB-1f80A:
undetectable		 4ikkA-1f80A:
24.24
4ikkB-1f80A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.89A 4iklA-1f80A:
undetectable
4iklB-1f80A:
undetectable		 4iklA-1f80A:
24.24
4iklB-1f80A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 8 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.90A 4iklA-1f80A:
undetectable
4iklB-1f80A:
undetectable		 4iklA-1f80A:
24.24
4iklB-1f80A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 8 LEU A  94
CYH A  91
PHE A  60
GLN A  71
 None
 1.06A 4j7uD-1f80A:
undetectable		 4j7uD-1f80A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 6 ALA A  51
ASP A   8
LEU A  12
SER A  17
 None
 1.15A 4ot2A-1f80A:
undetectable		 4ot2A-1f80A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 7 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.77A 4pwjB-1f80A:
undetectable		 4pwjB-1f80A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		5 / 9 ALA A  59
ILE A  15
ASP A   8
ALA A 111
THR A 104
 None
None
None
None
NA  A1255 (-3.8A)
 1.27A 4r1zA-1f80A:
undetectable		 4r1zA-1f80A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		5 / 11 THR A  10
GLN A 113
ALA A  51
GLY A  52
ALA A  56
 None
 1.20A 5bxnH-1f80A:
undetectable
5bxnI-1f80A:
undetectable		 5bxnH-1f80A:
20.26
5bxnI-1f80A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		5 / 11 THR A  10
GLN A 113
ALA A  51
GLY A  52
ALA A  56
 None
 1.20A 5bxnV-1f80A:
undetectable
5bxnW-1f80A:
undetectable		 5bxnV-1f80A:
20.26
5bxnW-1f80A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		4 / 7 ILE A 103
GLY A  52
PHE A  64
ASP A   8
 None
 0.98A 5hieA-1f80A:
undetectable		 5hieA-1f80A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		5 / 12 THR A  10
GLN A 113
ALA A  51
GLY A  52
ALA A  56
 None
 1.24A 5l5fH-1f80A:
undetectable
5l5fI-1f80A:
undetectable		 5l5fH-1f80A:
20.26
5l5fI-1f80A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		5 / 12 THR A  10
GLN A 113
ALA A  51
GLY A  52
ALA A  56
 None
 1.23A 5l5zH-1f80A:
0.1
5l5zI-1f80A:
undetectable		 5l5zH-1f80A:
20.26
5l5zI-1f80A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		5 / 12 THR A  10
GLN A 113
ALA A  51
GLY A  52
ALA A  56
 None
 1.28A 5l5zV-1f80A:
undetectable
5l5zW-1f80A:
undetectable		 5l5zV-1f80A:
20.26
5l5zW-1f80A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		5 / 12 THR A  10
GLN A 113
ALA A  51
GLY A  52
ALA A  56
 None
 1.19A 5l66H-1f80A:
undetectable
5l66I-1f80A:
undetectable		 5l66H-1f80A:
20.26
5l66I-1f80A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE
(Bacillus
subtilis) 		5 / 12 THR A  10
GLN A 113
ALA A  51
GLY A  52
ALA A  56
 None
 1.19A 5l66V-1f80A:
undetectable
5l66W-1f80A:
undetectable		 5l66V-1f80A:
20.26
5l66W-1f80A:
22.49