SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f89'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  83
LEU A  29
ALA A  32
LEU A  18
ILE A  99
 None
 1.10A 1crbA-1f89A:
undetectable		 1crbA-1f89A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  49
LEU A  94
LEU A  18
LEU A  51
PHE A  90
 None
 1.05A 1mx1F-1f89A:
undetectable		 1mx1F-1f89A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 236
GLN A  17
LEU A  15
CYH A 169
PHE A 195
 None
 1.39A 1p93B-1f89A:
undetectable		 1p93B-1f89A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 165
VAL A 166
SER A 181
ILE A 157
 None
 0.83A 1pk7B-1f89A:
undetectable		 1pk7B-1f89A:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 157
ALA A  87
ASN A  85
VAL A  80
ASN A 117
 None
 1.18A 2okcB-1f89A:
undetectable		 2okcB-1f89A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 130
ALA A 178
GLY A 165
VAL A 166
GLY A 167
 None
 1.18A 3f8wC-1f89A:
undetectable		 3f8wC-1f89A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI201_1
(PROTEIN S100-A4)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		5 / 9 GLY A 167
PRO A 192
GLY A 151
CYH A  54
PHE A  55
 None
 1.11A 3ko0H-1f89A:
undetectable
3ko0I-1f89A:
undetectable		 3ko0H-1f89A:
18.02
3ko0I-1f89A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		4 / 7 GLY A 151
CYH A  54
PHE A  55
GLY A 167
 None
 0.94A 3ko0M-1f89A:
undetectable
3ko0P-1f89A:
undetectable		 3ko0M-1f89A:
18.02
3ko0P-1f89A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		4 / 7 GLY A 167
GLY A 151
CYH A  54
PHE A  55
 None
 0.81A 3ko0M-1f89A:
undetectable
3ko0P-1f89A:
undetectable		 3ko0M-1f89A:
18.02
3ko0P-1f89A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		5 / 9 ILE A  11
LEU A   7
ILE A 190
LYS A 184
GLY A 185
 None
 1.27A 3sj4X-1f89A:
undetectable		 3sj4X-1f89A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 237
HIS A 205
ILE A 239
 None
 0.69A 3u52A-1f89A:
0.0
3u52C-1f89A:
undetectable		 3u52A-1f89A:
18.00
3u52C-1f89A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		4 / 5 THR A  98
ILE A  99
GLU A 101
PHE A 116
 None
 1.38A 4ac9C-1f89A:
undetectable		 4ac9C-1f89A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		4 / 5 THR A  98
ILE A  99
GLU A 101
PHE A 116
 None
 1.41A 4acaC-1f89A:
undetectable		 4acaC-1f89A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  11
ILE A 190
LYS A 184
GLY A 185
 None
 0.94A 4hdlA-1f89A:
0.0		 4hdlA-1f89A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		3 / 3 SER A 238
ALA A 249
VAL A 248
 None
 0.62A 4o2bC-1f89A:
undetectable		 4o2bC-1f89A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 1f89 32.5 KDA PROTEIN
YLR351C
(Saccharomyces
cerevisiae) 		3 / 3 SER A 238
ALA A 249
VAL A 248
 None
 0.54A 5xiwC-1f89A:
0.1		 5xiwC-1f89A:
15.88