SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f8r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		4 / 8 GLY A 239
GLU A 235
PHE A 362
HIS A 360
 None
 0.90A 1ax9A-1f8rA:
undetectable		 1ax9A-1f8rA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 12 ILE A 408
TYR A 357
VAL A 393
ILE A 327
SER A 415
 None
 1.18A 1fm4A-1f8rA:
undetectable		 1fm4A-1f8rA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_B_HISB450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 12 GLU A 167
TYR A 180
TYR A 188
GLY A 193
TYR A 183
 None
 1.10A 1httB-1f8rA:
2.0		 1httB-1f8rA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		4 / 4 LEU A  91
ILE A 430
ARG A 322
TRP A 420
 None
FAD  A 527 (-4.7A)
CIT  A 526 (-3.3A)
FAD  A 527 (-3.8A)
 1.38A 1ie9A-1f8rA:
0.0		 1ie9A-1f8rA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 10 ASP A 338
PHE A 335
SER A 346
ILE A 400
ILE A 369
 None
 1.32A 1j3jA-1f8rA:
undetectable		 1j3jA-1f8rA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		4 / 8 GLY A  87
ARG A  71
ILE A 430
ASP A 423
 FAD  A 527 (-3.9A)
FAD  A 527 (-4.0A)
FAD  A 527 (-4.7A)
None
 0.79A 1jg4A-1f8rA:
2.7		 1jg4A-1f8rA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		4 / 8 TYR A 157
VAL A 164
HIS A 223
GLU A 158
 None
None
CIT  A 526 (-3.6A)
None
 1.23A 1s3zA-1f8rA:
undetectable
1s3zB-1f8rA:
undetectable		 1s3zA-1f8rA:
14.60
1s3zB-1f8rA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		4 / 6 GLU A  93
LEU A  91
ARG A 232
PHE A 233
 None
 1.06A 1s8fB-1f8rA:
undetectable		 1s8fB-1f8rA:
18.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		7 / 7 ARG A  90
ASN A 208
HIS A 223
PHE A 227
TYR A 372
ILE A 430
TRP A 465
 CIT  A 526 ( 3.2A)
CIT  A 526 (-4.2A)
CIT  A 526 (-3.6A)
CIT  A 526 (-3.9A)
CIT  A 526 ( 4.8A)
FAD  A 527 (-4.7A)
None
 0.55A 1tdnA-1f8rA:
61.3		 1tdnA-1f8rA:
86.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		4 / 7 ARG A  90
HIS A 223
PHE A 227
ILE A 374
 CIT  A 526 ( 3.2A)
CIT  A 526 (-3.6A)
CIT  A 526 (-3.9A)
CIT  A 526 ( 4.9A)
 0.92A 1tdnA-1f8rA:
61.3		 1tdnA-1f8rA:
86.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		4 / 5 VAL A 480
ASN A 481
VAL A  36
ILE A 291
 None
 0.96A 1z2bC-1f8rA:
undetectable		 1z2bC-1f8rA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		4 / 7 GLY A 239
GLU A 235
PHE A 362
HIS A 360
 None
 0.85A 2ackA-1f8rA:
undetectable		 2ackA-1f8rA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 12 GLY A  87
ASN A  85
LEU A 422
ASP A 423
PHE A 381
 FAD  A 527 (-3.9A)
None
None
None
None
 1.34A 2b9eA-1f8rA:
2.2		 2b9eA-1f8rA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		3 / 3 LYS A 124
GLY A 198
PRO A 197
 None
 0.97A 2hreB-1f8rA:
0.0		 2hreB-1f8rA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		4 / 6 PRO A  68
GLY A  42
ILE A  38
GLY A  40
 None
FAD  A 527 (-3.5A)
None
FAD  A 527 (-3.3A)
 0.86A 2jkjA-1f8rA:
0.0		 2jkjA-1f8rA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		4 / 6 PRO A  68
GLY A  42
ILE A  38
GLY A  40
 None
FAD  A 527 (-3.5A)
None
FAD  A 527 (-3.3A)
 0.86A 2jkjB-1f8rA:
0.0		 2jkjB-1f8rA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		4 / 6 PRO A  68
GLY A  42
ILE A  38
GLY A  40
 None
FAD  A 527 (-3.5A)
None
FAD  A 527 (-3.3A)
 0.86A 2jkjC-1f8rA:
0.0		 2jkjC-1f8rA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		3 / 3 SER A 113
ARG A  90
GLN A 114
 None
CIT  A 526 ( 3.2A)
None
 0.97A 2xnrA-1f8rA:
1.7		 2xnrA-1f8rA:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 12 LEU A 195
VAL A 200
VAL A 165
ASN A   5
TYR A 188
 None
 1.45A 2y00A-1f8rA:
undetectable		 2y00A-1f8rA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 12 LEU A 195
VAL A 200
VAL A 165
ASN A   5
TYR A 188
 None
 1.42A 2y00B-1f8rA:
undetectable		 2y00B-1f8rA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 12 LEU A 195
VAL A 200
VAL A 165
ASN A   5
TYR A 188
 None
 1.45A 2y01B-1f8rA:
undetectable		 2y01B-1f8rA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		4 / 5 LEU A  91
ILE A 430
ARG A 322
TRP A 420
 None
FAD  A 527 (-4.7A)
CIT  A 526 (-3.3A)
FAD  A 527 (-3.8A)
 1.45A 2zlcA-1f8rA:
0.0		 2zlcA-1f8rA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 9 LEU A 207
VAL A 200
ILE A 190
GLY A 193
ILE A 203
 None
 1.13A 3ekqB-1f8rA:
undetectable		 3ekqB-1f8rA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 12 ILE A 262
VAL A 299
VAL A  39
VAL A 290
VAL A 273
 None
None
FAD  A 527 (-4.7A)
None
None
 1.07A 3iw1A-1f8rA:
0.0		 3iw1A-1f8rA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		3 / 3 THR A 431
VAL A 319
GLU A 219
 None
 0.63A 3v4tA-1f8rA:
0.0
3v4tD-1f8rA:
0.0		 3v4tA-1f8rA:
21.89
3v4tD-1f8rA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 8 LEU A   7
LYS A 222
TYR A 180
TYR A 188
LEU A 161
 None
 1.48A 3v81A-1f8rA:
2.8		 3v81A-1f8rA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		3 / 3 PHE A 112
VAL A  98
ILE A 102
 None
 0.58A 4emaA-1f8rA:
0.0		 4emaA-1f8rA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		3 / 3 LYS A 145
PRO A 146
SER A 147
 None
 0.40A 4k50I-1f8rA:
0.0		 4k50I-1f8rA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		3 / 3 LEU A 189
LYS A 186
THR A 185
 None
 0.62A 4lj0A-1f8rA:
0.0		 4lj0A-1f8rA:
7.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 9 LEU A   7
LYS A 222
TYR A 180
TYR A 188
LEU A 161
 None
 1.46A 4q0bC-1f8rA:
2.8		 4q0bC-1f8rA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 11 THR A 295
GLY A  42
GLY A  45
ALA A  44
SER A 472
 FAD  A 527 (-4.5A)
FAD  A 527 (-3.5A)
None
FAD  A 527 (-3.3A)
None
 0.99A 4qvlK-1f8rA:
undetectable
4qvlL-1f8rA:
undetectable		 4qvlK-1f8rA:
17.47
4qvlL-1f8rA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 11 THR A 295
GLY A  42
GLY A  45
ALA A  44
SER A 472
 FAD  A 527 (-4.5A)
FAD  A 527 (-3.5A)
None
FAD  A 527 (-3.3A)
None
 0.99A 4qvlY-1f8rA:
undetectable
4qvlZ-1f8rA:
undetectable		 4qvlY-1f8rA:
17.47
4qvlZ-1f8rA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 10 THR A 295
GLY A  42
GLY A  45
ALA A  44
SER A 472
 FAD  A 527 (-4.5A)
FAD  A 527 (-3.5A)
None
FAD  A 527 (-3.3A)
None
 0.96A 4qvmY-1f8rA:
undetectable
4qvmZ-1f8rA:
undetectable		 4qvmY-1f8rA:
17.47
4qvmZ-1f8rA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 11 THR A 295
GLY A  42
GLY A  45
ALA A  44
SER A 472
 FAD  A 527 (-4.5A)
FAD  A 527 (-3.5A)
None
FAD  A 527 (-3.3A)
None
 0.95A 4qw1K-1f8rA:
undetectable
4qw1L-1f8rA:
undetectable		 4qw1K-1f8rA:
17.67
4qw1L-1f8rA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		4 / 8 ALA A 455
GLY A 473
ALA A  48
GLY A  45
 None
 0.70A 4zjzA-1f8rA:
undetectable		 4zjzA-1f8rA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 11 THR A 295
GLY A  42
GLY A  45
ALA A  44
SER A 472
 FAD  A 527 (-4.5A)
FAD  A 527 (-3.5A)
None
FAD  A 527 (-3.3A)
None
 0.96A 5bxnK-1f8rA:
undetectable
5bxnL-1f8rA:
undetectable		 5bxnK-1f8rA:
17.47
5bxnL-1f8rA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 11 THR A 295
GLY A  42
GLY A  45
ALA A  44
SER A 472
 FAD  A 527 (-4.5A)
FAD  A 527 (-3.5A)
None
FAD  A 527 (-3.3A)
None
 0.96A 5bxnY-1f8rA:
undetectable
5bxnZ-1f8rA:
undetectable		 5bxnY-1f8rA:
17.47
5bxnZ-1f8rA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_1
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 12 GLY A 373
ARG A 322
PHE A 354
THR A 347
TYR A 121
 None
CIT  A 526 (-3.3A)
None
None
None
 1.46A 5nknA-1f8rA:
0.7		 5nknA-1f8rA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 12 LEU A  52
ILE A 291
VAL A 271
LEU A 482
ALA A 483
 None
 1.13A 6djzA-1f8rA:
0.0		 6djzA-1f8rA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 10 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
 None
 1.04A 6ebpD-1f8rA:
undetectable		 6ebpD-1f8rA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 11 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
 None
 1.02A 6ebzA-1f8rA:
undetectable		 6ebzA-1f8rA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 11 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
 None
 1.00A 6ebzB-1f8rA:
undetectable		 6ebzB-1f8rA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 11 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
 None
 1.00A 6ebzD-1f8rA:
undetectable		 6ebzD-1f8rA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		4 / 7 ARG A  71
LEU A 316
TYR A 321
VAL A 299
 FAD  A 527 (-4.0A)
None
None
None
 0.96A 6g2pA-1f8rA:
31.9		 6g2pA-1f8rA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 11 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
 None
 0.99A 6gp2A-1f8rA:
undetectable		 6gp2A-1f8rA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1f8r L-AMINO ACID OXIDASE
(Calloselasma
rhodostoma) 		5 / 11 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
 None
 0.98A 6gp2B-1f8rA:
undetectable		 6gp2B-1f8rA:
10.00