SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f8v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 1f8v MATURE CAPSID
PROTEIN BETA
(Pariacoto
virus) 		4 / 8 PRO A 112
GLY A 113
PHE A 261
THR A 285
 None
 0.79A 1h4oB-1f8vA:
undetectable		 1h4oB-1f8vA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 1f8v MATURE CAPSID
PROTEIN BETA
(Pariacoto
virus) 		4 / 8 PRO A 112
GLY A 113
PHE A 261
THR A 285
 None
 0.80A 1oc3A-1f8vA:
undetectable		 1oc3A-1f8vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1f8v MATURE CAPSID
PROTEIN BETA
MATURE CAPSID
PROTEIN GAMMA
(Pariacoto
virus;
Pariacoto
virus) 		4 / 6 ALA A 341
TYR D 400
ILE A  77
PRO A  78
 None
 1.18A 1oniB-1f8vA:
0.0
1oniC-1f8vA:
0.0		 1oniB-1f8vA:
18.46
1oniC-1f8vA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1f8v MATURE CAPSID
PROTEIN BETA
MATURE CAPSID
PROTEIN GAMMA
(Pariacoto
virus;
Pariacoto
virus) 		4 / 7 TYR D 400
ILE A  77
PRO A  78
ALA A 341
 None
 1.17A 1oniD-1f8vD:
undetectable
1oniE-1f8vD:
undetectable		 1oniD-1f8vD:
13.24
1oniE-1f8vD:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1f8v MATURE CAPSID
PROTEIN BETA
MATURE CAPSID
PROTEIN GAMMA
(Pariacoto
virus;
Pariacoto
virus) 		4 / 6 ALA A 341
TYR D 400
ILE A  77
PRO A  78
 None
 1.17A 1oniH-1f8vA:
0.0
1oniI-1f8vA:
0.0		 1oniH-1f8vA:
18.46
1oniI-1f8vA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1f8v MATURE CAPSID
PROTEIN BETA
(Pariacoto
virus) 		4 / 7 GLY A 149
PRO A 112
ASN A 155
ASN A 154
 None
 0.94A 1oniG-1f8vA:
0.0
1oniI-1f8vA:
0.0		 1oniG-1f8vA:
18.46
1oniI-1f8vA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 1f8v MATURE CAPSID
PROTEIN BETA
(Pariacoto
virus) 		3 / 3 ASN A 195
ALA A 193
ARG A 215
 None
 0.56A 3tj7C-1f8vA:
0.0
3tj7D-1f8vA:
0.0		 3tj7C-1f8vA:
17.32
3tj7D-1f8vA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 1f8v MATURE CAPSID
PROTEIN BETA
(Pariacoto
virus) 		4 / 6 CYH A 316
CYH A  62
GLY A  74
ASP A  72
 None
 1.22A 3w9tE-1f8vA:
0.0		 3w9tE-1f8vA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1f8v MATURE CAPSID
PROTEIN BETA
(Pariacoto
virus) 		5 / 11 ALA A 109
LEU A 275
PHE A 117
PHE A 159
ILE A 317
 None
 1.29A 4claA-1f8vA:
0.0		 4claA-1f8vA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 1f8v MATURE CAPSID
PROTEIN BETA
MATURE CAPSID
PROTEIN GAMMA
(Pariacoto
virus) 		5 / 9 PRO A 353
VAL A 356
ALA A 355
TYR A 240
GLY D 367
 None
 1.30A 4mm5A-1f8vA:
0.0		 4mm5A-1f8vA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 1f8v MATURE CAPSID
PROTEIN BETA
MATURE CAPSID
PROTEIN GAMMA
(Pariacoto
virus) 		5 / 9 PRO A 353
VAL A 356
ALA A 355
TYR A 240
GLY D 367
 None
 1.33A 4mmbA-1f8vA:
0.0		 4mmbA-1f8vA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 1f8v MATURE CAPSID
PROTEIN BETA
(Pariacoto
virus) 		4 / 6 VAL A 123
ASP A 103
SER A 180
ALA A 226
 None
 1.16A 4nedA-1f8vA:
undetectable		 4nedA-1f8vA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_1
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 1f8v MATURE CAPSID
PROTEIN BETA
(Pariacoto
virus) 		4 / 5 TYR A 135
ASP A  72
ASP A  68
TYR A 240
 None
 1.43A 4qdjA-1f8vA:
undetectable		 4qdjA-1f8vA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 1f8v MATURE CAPSID
PROTEIN BETA
(Pariacoto
virus) 		5 / 12 LEU A 219
LEU A 275
PHE A 159
LEU A 190
ILE A 216
 None
 1.13A 4x1fA-1f8vA:
0.0		 4x1fA-1f8vA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 1f8v MATURE CAPSID
PROTEIN BETA
(Pariacoto
virus) 		5 / 12 LEU A 219
LEU A 275
PHE A 159
LEU A 190
ILE A 216
 None
 1.13A 4x1gA-1f8vA:
0.0		 4x1gA-1f8vA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 1f8v MATURE CAPSID
PROTEIN BETA
MATURE CAPSID
PROTEIN GAMMA
(Pariacoto
virus;
Pariacoto
virus) 		5 / 12 LEU A  52
GLY D 398
ASN A  49
LEU D 396
CYH A 344
 None
 1.22A 4x61A-1f8vA:
0.0		 4x61A-1f8vA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1f8v MATURE CAPSID
PROTEIN BETA
(Pariacoto
virus) 		5 / 12 GLY A 113
THR A 137
PHE A 159
ILE A 317
PHE A 255
 None
 1.27A 4zvmA-1f8vA:
undetectable
4zvmB-1f8vA:
undetectable		 4zvmA-1f8vA:
19.38
4zvmB-1f8vA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 1f8v MATURE CAPSID
PROTEIN BETA
(Pariacoto
virus) 		4 / 6 PHE A 130
LEU A 276
ARG A 118
GLY A 132
 None
 1.11A 5o4yA-1f8vA:
undetectable		 5o4yA-1f8vA:
3.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 1f8v MATURE CAPSID
PROTEIN BETA
(Pariacoto
virus) 		4 / 6 PHE A 261
LEU A 188
SER A 191
ARG A 215
 None
 1.09A 5o4yF-1f8vA:
undetectable		 5o4yF-1f8vA:
3.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 1f8v MATURE CAPSID
PROTEIN BETA
(Pariacoto
virus) 		3 / 3 PHE A  81
ARG A 160
GLN A 320
 None
 1.10A 6g1pB-1f8vA:
0.0		 6g1pB-1f8vA:
23.71