SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f8y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 1f8y NUCLEOSIDE
2-DEOXYRIBOSYLTRANSF
ERASE
(Lactobacillus
leichmannii) 		5 / 8 ILE A  34
LEU A  36
MET A  25
GLU A  26
ALA A  27
 None
 1.47A 1a29A-1f8yA:
undetectable		 1a29A-1f8yA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 1f8y NUCLEOSIDE
2-DEOXYRIBOSYLTRANSF
ERASE
(Lactobacillus
leichmannii) 		6 / 12 ILE A 134
VAL A 112
PHE A 142
LEU A  83
VAL A  85
LEU A  28
 None
 1.46A 2aw1A-1f8yA:
0.0		 2aw1A-1f8yA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 1f8y NUCLEOSIDE
2-DEOXYRIBOSYLTRANSF
ERASE
(Lactobacillus
leichmannii) 		5 / 10 PHE A  13
GLY A  11
ALA A  10
TYR A  21
ASP A  92
 5MD  A 158 (-4.8A)
5MD  A 158 ( 4.1A)
None
None
5MD  A 158 (-2.8A)
 1.41A 2xtkB-1f8yA:
undetectable		 2xtkB-1f8yA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 1f8y NUCLEOSIDE
2-DEOXYRIBOSYLTRANSF
ERASE
(Lactobacillus
leichmannii) 		5 / 12 PHE A   8
LEU A  28
VAL A  85
LEU A  83
ILE A 134
 None
 0.99A 4g1bA-1f8yA:
3.3		 4g1bA-1f8yA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1f8y NUCLEOSIDE
2-DEOXYRIBOSYLTRANSF
ERASE
(Lactobacillus
leichmannii) 		3 / 3 ASP A  80
VAL A 109
ASN A 145
 None
 0.79A 4lmnA-1f8yA:
0.0		 4lmnA-1f8yA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1f8y NUCLEOSIDE
2-DEOXYRIBOSYLTRANSF
ERASE
(Lactobacillus
leichmannii) 		3 / 3 VAL A  85
TYR A  21
GLN A  17
 None
 0.74A 5qgkA-1f8yA:
0.0		 5qgkA-1f8yA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1f8y NUCLEOSIDE
2-DEOXYRIBOSYLTRANSF
ERASE
(Lactobacillus
leichmannii) 		3 / 3 VAL A  85
TYR A  21
GLN A  17
 None
 0.75A 5qgrA-1f8yA:
undetectable		 5qgrA-1f8yA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1f8y NUCLEOSIDE
2-DEOXYRIBOSYLTRANSF
ERASE
(Lactobacillus
leichmannii) 		3 / 3 VAL A  85
TYR A  21
GLN A  17
 None
 0.72A 5qgtA-1f8yA:
undetectable		 5qgtA-1f8yA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 1f8y NUCLEOSIDE
2-DEOXYRIBOSYLTRANSF
ERASE
(Lactobacillus
leichmannii) 		3 / 3 TYR A  21
ALA A  27
LEU A  28
 None
 0.58A 6ag0C-1f8yA:
undetectable		 6ag0C-1f8yA:
22.15