SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f9k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		5 / 12 GLY A  89
ALA A  87
PHE A 127
THR A 126
LEU A 155
 None
AMG  A 400 ( 3.7A)
AMG  A 400 ( 3.6A)
None
None
 0.59A 3dh0A-1f9kA:
undetectable		 3dh0A-1f9kA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		5 / 10 PHE A  75
ASN A 162
PHE A 180
ALA A 179
ILE A 138
 None
 1.30A 3t3qA-1f9kA:
undetectable		 3t3qA-1f9kA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		5 / 10 PHE A  75
PHE A 180
ALA A 179
ILE A 138
PHE A 124
 None
 1.24A 3t3qA-1f9kA:
undetectable		 3t3qA-1f9kA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		5 / 10 PHE A  75
ASN A 162
PHE A 180
ALA A 179
ILE A 138
 None
 1.29A 3t3qB-1f9kA:
undetectable		 3t3qB-1f9kA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		5 / 10 PHE A  75
PHE A  73
PHE A 180
ILE A 138
PHE A 124
 None
 1.27A 3t3qB-1f9kA:
undetectable		 3t3qB-1f9kA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		5 / 10 PHE A  75
PHE A 180
ALA A 179
ILE A 138
PHE A 124
 None
 1.21A 3t3qB-1f9kA:
undetectable		 3t3qB-1f9kA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		5 / 10 PHE A  75
PHE A 180
ALA A 179
ILE A 138
PHE A 124
 None
 1.18A 3t3qC-1f9kA:
undetectable		 3t3qC-1f9kA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		6 / 10 PHE A  75
PHE A  73
PHE A 180
ALA A 179
ILE A 138
PHE A 124
 None
 1.33A 3t3qD-1f9kA:
undetectable		 3t3qD-1f9kA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		4 / 4 PHE A  93
VAL A  95
ALA A 121
PHE A 199
 None
 1.37A 4f3tA-1f9kA:
0.0		 4f3tA-1f9kA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		4 / 5 VAL A 122
LEU A 174
VAL A 193
PHE A 120
 None
 1.02A 4lb0B-1f9kA:
0.0		 4lb0B-1f9kA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		4 / 4 PHE A  93
VAL A  95
ALA A 121
PHE A 199
 None
 1.41A 4w5qA-1f9kA:
0.0		 4w5qA-1f9kA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		4 / 4 PHE A  93
VAL A  95
ALA A 121
PHE A 199
 None
 1.35A 4w5rA-1f9kA:
undetectable		 4w5rA-1f9kA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		4 / 4 PHE A  93
VAL A  95
ALA A 121
PHE A 199
 None
 1.37A 4w5tA-1f9kA:
undetectable		 4w5tA-1f9kA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		4 / 4 PHE A  93
VAL A  95
ALA A 121
PHE A 199
 None
 1.40A 4z4gA-1f9kA:
undetectable		 4z4gA-1f9kA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		5 / 12 GLY A 158
GLY A 106
THR A 212
PHE A 153
THR A  78
 NAG  A 501 (-4.2A)
AMG  A 400 (-3.2A)
None
None
NAG  A 503 ( 3.9A)
 1.26A 5eslA-1f9kA:
undetectable		 5eslA-1f9kA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		4 / 8 TYR A 215
THR A 212
THR A  47
PRO A 113
 AMG  A 400 (-4.6A)
None
None
None
 1.12A 5jhdE-1f9kA:
1.4
5jhdG-1f9kA:
0.3		 5jhdE-1f9kA:
22.56
5jhdG-1f9kA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		4 / 4 PHE A  93
VAL A  95
ALA A 121
PHE A 199
 None
 1.38A 5ki6A-1f9kA:
0.0		 5ki6A-1f9kA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		5 / 12 ILE A  77
LEU A 155
PRO A  86
GLY A  89
ASP A 125
 None
None
None
None
CA  A 302 ( 2.2A)
 1.14A 5nnaC-1f9kA:
undetectable		 5nnaC-1f9kA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		5 / 12 ILE A  77
LEU A 155
PRO A  86
GLY A  89
ASP A 125
 None
None
None
None
CA  A 302 ( 2.2A)
 1.17A 5nnaD-1f9kA:
undetectable		 5nnaD-1f9kA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		4 / 7 THR A  34
VAL A 135
GLN A 154
GLU A 156
 None
 1.05A 5tudA-1f9kA:
undetectable		 5tudA-1f9kA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1f9k ACIDIC LECTIN
(Psophocarpus
tetragonolobus) 		4 / 6 ASP A 125
GLN A 128
VAL A 135
GLU A 123
 CA  A 302 ( 2.2A)
None
None
MN  A 300 (-3.0A)
 1.02A 6djzB-1f9kA:
0.1		 6djzB-1f9kA:
22.49