SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1f9n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A50_C_VD3C2001_1 (VITAMIN D HYDROXYLASE)	1f9n	ARGININE REPRESSOR/ACTIVATOR PROTEIN (Bacillus subtilis)	5 / 11	ILE A 130 LEU A 146 ILE A 87 THR A 98 LEU A 80	None	1.24A	3a50C-1f9nA: undetectable	3a50C-1f9nA: 17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A50_E_VD3E2001_1 (VITAMIN D HYDROXYLASE)	1f9n	ARGININE REPRESSOR/ACTIVATOR PROTEIN (Bacillus subtilis)	5 / 12	ILE A 130 LEU A 146 ILE A 87 THR A 98 LEU A 80	None	1.22A	3a50E-1f9nA: 0.0	3a50E-1f9nA: 17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R87_H_SPMH202_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	1f9n	ARGININE REPRESSOR/ACTIVATOR PROTEIN (Bacillus subtilis)	4 / 6	ASN A 17 GLU A 18 TYR A 62 GLU A 24	None	1.24A	4r87H-1f9nA: undetectable	4r87H-1f9nA: 23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AJQ_B_DB8B800_1 (SERINE/THREONINE-PRO TEIN KINASE 10)	1f9n	ARGININE REPRESSOR/ACTIVATOR PROTEIN (Bacillus subtilis)	4 / 10	ALA A 105 ILE A 106 ALA A 83 ASP A 82	None	0.43A	5ajqB-1f9nA: undetectable	5ajqB-1f9nA: 20.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3A50_C_VD3C2001_1","VITAMIN D HYDROXYLASE","1f9n","ARGININE REPRESSOR\/ACTIVATOR PROTEIN","Bacillus subtilis",5,"ILE A 130;LEU A 146;ILE A  87;THR A  98;LEU A  80","None","1.24A","3a50C-1f9nA:undetectable","3a50C-1f9nA:17.20"],["3A50_E_VD3E2001_1","VITAMIN D HYDROXYLASE","1f9n","ARGININE REPRESSOR\/ACTIVATOR PROTEIN","Bacillus subtilis",5,"ILE A 130;LEU A 146;ILE A  87;THR A  98;LEU A  80","None","1.22A","3a50E-1f9nA:0.0","3a50E-1f9nA:17.20"],["4R87_H_SPMH202_1","SPERMIDINE N1-ACETYLTRANSFERASE","1f9n","ARGININE REPRESSOR\/ACTIVATOR PROTEIN","Bacillus subtilis",4,"ASN A  17;GLU A  18;TYR A  62;GLU A  24","None","1.24A","4r87H-1f9nA:undetectable","4r87H-1f9nA:23.20"],["5AJQ_B_DB8B800_1","SERINE\/THREONINE-PROTEIN KINASE 10","1f9n","ARGININE REPRESSOR\/ACTIVATOR PROTEIN","Bacillus subtilis",4,"ALA A 105;ILE A 106;ALA A  83;ASP A  82","None","0.43A","5ajqB-1f9nA:undetectable","5ajqB-1f9nA:20.21"]]